Endothelial colony-forming cells
Potential long-term treatment of hemophilia A by neonatal co-transplantation of cord blood-derived endothelial colony-forming cells and placental mesenchymal stromal cells
... Since endothelial cells (ECs) are the primary source of FVIII in the body [12, 13], a number of studies have shown that ECs and endothelial progenitor cells (EPCs) can correct the phenotype in ...
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3D co-culture model of endothelial colony-forming cells (ECFCs) reverses late passage adipose-derived stem cell senescence for wound healing
... Endothelial colony-forming cells (ECFCs) are a type of progenitor cell circulating in the blood that can differen- tiate into several endothelial lineage ...
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Expression of Protease-Activated Receptor 1 and 2 and Anti-Tubulogenic Activity of Protease-Activated Receptor 1 in Human Endothelial Colony-Forming Cells
... Endothelial colony-forming cells (ECFCs) are obtained from the culture of human peripheral blood mononuclear cell (hPBMNC) fractions and are characterised by high proliferative and ...
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Acidic preconditioning of endothelial colony-forming cells (ECFC) promote vasculogenesis under proinflammatory and high glucose conditions in vitro and in vivo
... Effective endothelial repair and de- velopment of new vessels requires the contribution of both angiogenesis, mediated by mature endothelial cells in nearby tissues, and vasculogenesis, supported by ...
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Hypoxia accelerates vascular repair of endothelial colony-forming cells on ischemic injury via STAT3-BCL3 axis
... this ECFC bioactivity was rescued by co-culture with MSC/progenitor cells. This discrepancy in response of hypoxia on ECFC could be explained by differences in the oxygen concentration and duration of hypoxia. ...
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Osteoprotegerin, a new actor in vasculogenesis, stimulates endothelial colony-forming cells properties
... Progenitor Cells (EPC) are marrow-derived circulating cells involved in postnatal ...These cells are recruited from bone marrow and are incorporated into sites of active revascularization, attracted ...
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Cord blood-endothelial colony forming cells are immunotolerated and participate at post-ischemic angiogenesis in an original dorsal chamber immunocompetent mouse model
... mononuclear cells; CD: Cluster differentiation; CFU-ECs: Colony forming unit- endothelial cells; CSF-2: Colony-stimulating factor-2; DAPI: 40,6-Diamidino-2- phenylindole; DNA: ...
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Endothelial Colony Forming Cells (ECFCs) in murine AKI – implications for future cell-based therapies
... epithelial cells (Epithelial-to-Mesenchymal Transition – EMT ...mature endothelial cells within peritub- ular vessels (capillaries, ...revealed Endothelial-to-Mesenchymal Transition (EndoMT) ...
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Hypoxia-induced responses by endothelial colony-forming cells are modulated by placental growth factor
... muscle cells, HIF-1α expression decreased cell migration and adherence to the ECM, with no evident changes in vincullin or focal adhesion kinase (FAK) local- isation ...
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Tumor-tropic endothelial colony forming cells (ECFCs) loaded with near-infrared sensitive Au nanoparticles: A “cellular stove” approach to the photoablation of melanoma
... Anticancer drugs encounter several challenges to their therapeutic efficacy, including short half-life, drug resistance, and nonspecific distribution with potential side effects to healthy organs. Nanotechnology provides ...
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Early outgrowth cells versus endothelial colony forming cells functions in platelet aggregation
... progenitor cells are regarded as promising therapeutic tools for vascular repair, tissue engineer- ing, and regenerative ...these cells is hindered by the existence of diverse subtypes of EPCs which exert ...
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CD44 expression in endothelial colony-forming cells regulates neurovascular trophic effect
... Mononuclear cells were isolated from UCB by Lymphoprep (STEM- CELL Technologies, 07851), resuspended into complete EGM-2 medium (SCM) (EGM-2 bullet kit, Lonza, cc-3202, and 10% FBS) or XFM provided by STEMCELL ...
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Endothelial colony-forming cells reduced the lung injury induced by cardiopulmonary bypass in rats
... After CPB, apoptosis also played a pivotal role in lung injury [40]. Both inflammatory factors (TNF-α) and re- active oxygen species induced by lung ischaemia lead to cell apoptosis [41]. The apoptotic endothelium and ...
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Progenitor cell combination normalizes retinal vascular development in the oxygen-induced retinopathy (OIR) model
... + cells and vascular wall–derived endothelial colony–forming cells (ECFCs), would synergistically protect the developing retinal vasculature in a mouse model of ROP, called ...
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Identification of mouse colony-forming endothelial progenitor cells for postnatal neovascularization: a novel insight highlighted by new mouse colony-forming assay
... primitive cells differen- tiated into two types of EPC colony clusters: large-EPC- CFUs and small-EPC-CFUs (Figure 1a, data not ...these cells are large-EPC-CFUs, which were composed mainly of ...
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NOS2 deficiency has no influence on the radiosensitivity of the hematopoietic system
... mononuclear cells; BFU-E: burst-forming unit erythroid; CFU-GM: colony forming unit-granulocyte, macrophage; CFU-GEMM: colony forming unit-granulocyte, erythroid, macrophage, ...
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Strategies for derivation of endothelial lineages from human stem cells
... progenitor cells capable of differentiation into functional ECs are termed as ...as colony-formingunit-endothelial cells (CFU-EC) [90], colony-formingunit-hill (CFU-Hill) [91], ...
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Genetic communication by extracellular vesicles is an important mechanism underlying stem cell-based therapy-mediated protection against acute kidney injury
... epithelial cells (TECs) and human umbilical vein endothelial cells (HUVECs) showed the incorporation of MSC-EVs and the transfer of ...the cells by con- focal ...of endothelial ...
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Retrovirus induced feline pure red cell aplasia Hematopoietic progenitors are infected with feline leukemia virus and erythroid burst forming cells are uniquely sensitive to heterologous complement
... mononuclear cells from cats viremic with FeLV-C were labeled with monoclonal antibodies to gp70 and then analyzed with a fluorescence-activated cell ...among cells sorting positively, suggesting that ...
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Clonal Expression of the Tn Antigen in Erythroid and Granulocyte Colonies and Its Application to Determination of the Clonality of the Human Megakaryocyte Colony Assay
... colonies, colony-forming unit granulocyte-macrophage (CFU-GM), and colony-forming unit-eosinophil (CFU-Eo) were grown from a blood group O patient with a typical Tn syndrome displaying two ...
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