Endothelial Nitric
Sphingosine-1-phosphate promotes the differentiation of adipose-derived stem cells into endothelial nitric oxide synthase (eNOS) expressing endothelial-like cells
... with endothelial cell growth supplement, human adipose-derived stem cells (ASCs) express endothelial specific markers such as platelet-endothelial cell adhesion molecule (PCAM-1 or CD31) and von ...
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Regulation of nitric oxide synthesis by proinflammatory cytokines in human umbilical vein endothelial cells Elevations in tetrahydrobiopterin levels enhance endothelial nitric oxide synthase specific activity
... Regulation of Nitric Oxide Synthesis by Proinflammatory Cytokines in Human Umbilical Vein Endothelial Cells Elevations in Tetrahydrobiopterin Levels Enhance Endothelial Nitric Oxide Synt[r] ...
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Serum Nitric Oxide Level and Endothelial Nitric Oxide Synthase Gene INTRON4 VNTR Polymorphism in Essential Hypertension.
... hypertension. Endothelial dysfunction which is now recognised to be the hallmark in the pathogenesis of essential hypertension, is mainly caused by imbalance between vasoconstrictors and vasodilators .... ...
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Hypercholesterolemia decreases nitric oxide production by promoting the interaction of caveolin and endothelial nitric oxide synthase
... aortic endothelial cells were cultured in the presence of serum obtained from normocholesterolemic (NC) or hypercholesterolemic (HC) human ...of endothelial cells to the HC serum upregulated caveolin ...
10
Endothelial nitric oxide synthase G894T polymorphism increases the risk of infertility in women with endometriosis
... Nitric oxide (NO) has long been known to have an important role in endometrial function (Chwalisz and Garfield, 2000). In the normal human endometrium, NO is synthesized by endothelial and inducible NO ...
10
Methylglyoxal modulates endothelial nitric oxide synthase-associated functions in EA.hy926 endothelial cells
... vascular endothelial cells in vitro, we analyzed MG-triggered O •− 2 generation using a fluorescence-based ...EA.hy926 endothelial cells with MG (50 – 200 μ M) for 2, 4, 6 and 8 h respectively, ...
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Low serum insulin-like growth factor-1 in patients with erectile dysfunction
... circulating nitric oxide (NO) bioavailability and vascular endothelial nitric oxide synthase (eNOS) expression, the main NO-producing enzyme in the vascular wall ...
6
The NO-cGMP-PKG signal transduction pathway is involved in the analgesic effect of early hyperbaric oxygen treatment of neuropathic pain
... CCI: Chronic constriction injury; cGMP: cyclic guanosine monophosphate; eNOS: endothelial nitric oxide synthase; HBO: Hyperbaric oxygen; iNOS: inducible nitric oxide synthase; L-NAME: N-[r] ...
8
Immunohistochemistry comparing endoscopic vein harvesting vs. open vein harvesting on saphenous vein endothelium
... [13]. Endothelial Nitric Oxide (eNOS), endothelial Caveolin (e-Caveolin), von Willebrand factor (vWf), and cadherin can evaluate endo- thelial function and damages ...[14]. Endothelial damage ...
6
miR-190a-5p participates in the regulation of hypoxia-induced pulmonary hypertension by targeting KLF15 and can serve as a biomarker of diagnosis and prognosis in chronic obstructive pulmonary disease complicated with pulmonary hypertension
... enOs, endothelial nitric oxide synthase; hPaeCs, human pulmonary arterial endothelial cells; KlF15, Krüppel-like factor 15; Mut, mutant; WT, wild ...
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MeCP2-mediated epigenetic regulation in senescent endothelial progenitor cells
... transgenic mice [27]. Here we found that MeCP2 ap- peared as a nucleus and cytoplasm protein. SIRT1 is pre- dominantly localized in the nucleus [28], and we found the same location. SIRT1 promotes vascular relaxation by ...
7
The Evaluation of Serum Nitrite, Nitrate and Malonyldialdehyde Levels in Smokers
... on endothelial nitric oxide synthase gene expression and enzyme ...on nitric oxide synthase expression in the rat ...SP. Nitric oxide and the ...
7
The role of nitric oxide in childhood hypertension and a critical analysis of the measurement and interpretation of blood pressure
... in endothelial nitric oxide generation, and thereby maintain normal vascular tone, hence blood pressure^^^ For instance, in humans too it is likely that some may be susceptible to influences o f raised ADMA ...
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eNOS polymorphisms as predictors of efficacy of bevacizumab based chemotherapy in metastatic colorectal cancer: data from a randomized clinical trial
... and endothelial nitric oxide synthase (eNOS) polymorphisms were asso- ciated with sunitinib-induced hypertension in patients with metastatic renal cancer, with grade three hyperten- sion identified as an ...
10
Role of the vascular endothelium and plaque in acute ischemic stroke
... arterial endothelial cell ...associated endothelial damage by initiating and promoting the deposition of modified lipids in the subendo- thelium and by inhibiting endothelial nitric oxide (NO) ...
6
POSSIBLE THERAPEUTIC POTENTIAL OF STATIN INDEPENDENT OF LIPID-LOWERING ACTIVITY
... to interfere with mevalonate pathway and subsequent inhibhition of prenylation of Rho family GTPases [18-21]. Macrophages are capable of degrading the extracellular matrix and, by secreting matrix metalloproteinase (MMP) ...
10
Fatty acid-binding protein 4 impairs the insulin-dependent nitric oxide pathway in vascular endothelial cells
... as nitric oxide (NO) and vasoconstricting ...reflect endothelial function, and its impairment is predictive of future cardiovascular risk ...of endothelial nitric oxide synthase (eNOS) and an ...
8
Lancemaside A, a major triterpene saponin of Codonopsis lanceolata enhances regulation of nitric oxide synthesis via eNOS activation
... Endothelial nitric oxide synthase (eNOS), which synthesizes a nanomolar amount of nitric oxide (NO), is an isozyme of NOS; other NOS isozymes include neuronal NOS (nNOS), inducible NOS (iNOS), and ...
9
Association between NOS3 G894T, T-786C and 4a/4b Variants and Coronary Artery Diseases in Iranian Population
... Background: Endothelial nitric oxide synthase, encoded by NOS3, produces an atheroprotective metabolite. The G894T, T-786C and 4a/4b variants of this gene associated with increased risk for coronary artery ...
8
Koltermann, Anja (2008): Influence of Ginkgo biloba extract EGb 761 on signaling pathways in endothelial cells. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... of endothelial nitric oxide ...an endothelial-like cell model and the observation time was relatively short compared to our settings (only 2 or 4 ...
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