Endothelial permeability
Interaction between mesenchymal stem cells and endothelial cells restores endothelial permeability via paracrine hepatocyte growth factor in vitro
... the endothelial permeability induced by LPS under two co-culture ...microvascular endothelial cells (HPMECs) were added into the upper chambers of cell-culture inserts, while two different co-culture ...
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Role of phosphodiesterases in the regulation of endothelial permeability in vitro
... an endothelial cell monolayer derived from porcine pulmonary ...on endothelial permeability were completely inhibited by adenylate cyclase activation with 10(-12) M cholera toxin or ...
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Dengue virus–elicited tryptase induces endothelial permeability and shock
... vascular permeability and may result in replication of virus within cell types that would be resistant to infection in IFN-competent animals ...vascular permeability, further studies are needed to reconcile ...
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Potentiating angiogenesis arrest in vivo via laser irradiation of peptide functionalised gold nanoparticles
... and metalloproteinase 9 (MMP-9), when compared to the scramble peptide alone or conjugated to AuNPs—Fig. 5. MMP-9 is a matrix metalloproteinase involved in the breakdown of extracellular matrix, and facilitates the vas- ...
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Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy
... Background: Sepsis-associated encephalopathy (SAE), a diffuse cerebral dysfunction in the absence of direct CNS infection, is associated with increased rates of mortality and morbidity in patients with sepsis. Increased ...
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Increased endothelial albumin permeability mediated by protein kinase C activation
... 125I-albumin permeability induced by PMA was inhibited by 25 microM H7 (a PKC inhibitor), but not by the control compound HA1004 (25 ...125I-albumin permeability returned to baseline and a significant ...
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Mesenchymal stem cells microvesicles stabilize endothelial barrier function partly mediated by hepatocyte growth factor (HGF)
... reduced endothelial cell permeability via HGF There are two pathways regulating permeability across the endothelial barrier, paracellular and ...transcelluar permeability as well as ...
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Ophiopogon Saponin C1 Inhibits Lung Tumors by Stabilizing Endothelium Permeability via Inhibition of PKCδ
... vascular endothelial cells form the most important barrier to prevent tumor cell migration to the blood and ...vascular permeability provides favorable conditions for the migration of tumor cells, and ...
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A Vascular Permeability Assay Using an In Vitro Human Microvessel Model Mimicking the Inflammatory Condition
... a permeability coefficient, it is easy to set-up as no complicated analytical model is ...the endothelial permeability or strengthen the barrier function of endothelial ...excessive ...
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Effects of high glucose on human umbilical vein endothelial cell permeability and myosin light chain phosphorylation
... local endothelial cell injury. Endothelial cell injury can result in increased endothelial permeability and transendothe- lial transport of lipids and cellular blood components to the intima ...
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Distinct effects of glucose and glucosamine on vascular endothelial and smooth muscle cells: Evidence for a protective role for glucosamine in atherosclerosis
... increased endothelial permeability and increased smooth muscle cell (SMC) ...on endothelial cells and SMCs in vitro and on atherosclerosis in apoE null ...of endothelial cells with ...
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Nitric oxide deficiency and endothelial–mesenchymal transition of pulmonary endothelium in the progression of 4T1 metastatic breast cancer in mice
... increased endothelial permeability and early metastasis but is preceded by a clear-cut NO-deficiency state, that was detected as early as 1 week after 4T1 cancer cell inoculation in the premetastatic stage, ...
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<p>Functional Relevancies of Trans-Differentiation in the Juxtaglomerular Apparatus of Rat Kidney</p>
... The permeability of the afferent arteriolar endothelium increases with close- ness to the ...higher permeability portion of the endothelium and the renin-positive part of the afferent arteriole, a ...
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Association of Matrix Metalloproteinase-2 Gene Promoter Polymorphism and the Associated Phenotypic Variation with Myocardial Infarction.
... Coronary risk factors are resistance to insulin, hyperinsulinemia , hypertension, diabetes, hypertriglyceridemia, low HDL, predominance of small LDL, and elevated plasminogen activator inhibitor concentration 62,63 . ...
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“INVESTIGATION OF LIPID LOWERING ACTIVITY OF GSK-3 INHIBITOR” by Manish M. Patel, Kirankumar K. Shah, India.
... the permeability of endothelial monolayers, enhance lipid accumulation in SMCs, promote endothelial production of inflammatory mediators (NF-&B, IL-8, ICAM-1), and alter the extracellular matrix ...
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Recombinant antibody fragments to vascular associated targets of human tumours
... Sensitivity with this anti-His antibody was very low and so an alternative method needed to be designed. Direct biotinylation of the scFvs was considered the best option as it avoided used of detection systems involving ...
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Pathogenic Hantaviruses Andes Virus and Hantaan Virus Induce Adherens Junction Disassembly by Directing Vascular Endothelial Cadherin Internalization in Human Endothelial Cells
... FIG. 3. Quantification of VE-cadherin internalization and endo- thelial cell permeability. (A) Endothelial cells were infected and treated as described in the legend to Fig. 2B. The internalization of ...
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Chemical constituents and antihistamine activity of Bixa orellana leaf extract
... vascular permeability reflected in the decreased paw volume and Evans blue dye ...this permeability modulation by AEBO also involved the reduction of biochemical mediators such as NO and ...
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Monocyte migration into the subendothelial space of a coculture of adult human aortic endothelial and smooth muscle cells
... an endothelial monolayer. We conclude that (a) the endothelial monolayer was the principal permeability barrier, (b) a substantial migration of monocytes occurred in the absence of added ...
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Protein kinase C-delta inhibition protects blood-brain barrier from sepsis-induced vascular damage
... microvascular endothelial cell (HBMVEC), human astrocytes, endothelial cell media (ECM), and astro- cyte media were purchased from ScienCell (Carlsbad, ...
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