endothelium-derived relaxing factor
Modulation of angiotensin II induced vasoconstriction by endothelium derived relaxing factor in the isolated microperfused rabbit afferent arteriole
... Although endothelium-derived relaxing factor (EDRF) has been studied extensively in large vessels, little is known about its role in the preglomerular afferent arteriole ...
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Endothelium derived relaxing factor inhibits transport and increases cGMP content in cultured mouse cortical collecting duct cells
... of endothelium-derived relaxing factor (EDRF) in the kidney has been shown to result in natriuresis without affecting glomerular filtration ...
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Differential expression of mRNA for guanylyl cyclase linked endothelium derived relaxing factor receptor subunits in rat kidney
... Endothelium-derived relaxing factor (EDRF) has profound effects on the renal vasculature, the glomerular mesangium, and also affects renal salt ...
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Smooth muscle calcium and endothelium derived relaxing factor in the abnormal vascular responses of acute renal failure
... sensitivity to renal nerve stimulation (RNS), and loss of vasodilatation to acetylcholine have all been demonstrated in ischemic acute renal failure (ARF). To determine if ischemic injury alters vascular contractility by ...
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Involvement of endothelium derived relaxing factor in the pressure control of renin secretion from isolated perfused kidney
... Using isolated rat kidneys perfused at controlled pressure, we examined a potential role of endothelium-derived relaxing factor (EDRF) in the pressure control of renin secretion. We found that ...
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Adverse vascular effects of homocysteine are modulated by endothelium derived relaxing factor and related oxides of nitrogen
... compelling evidence that thiols react in the presence of nitric oxide (NO) and endothelium- derived relaxing factor (EDRF) to form S-nitrosothiols, compounds with potent vasodilatory and ...
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Vasodilator and constrictor actions of platelet activating factor in the isolated microperfused afferent arteriole of the rabbit kidney Role of endothelium derived relaxing factor/nitric oxide and cyclooxygenase products
... platelet-activating factor (PAF) plays a prominent role in the control of glomerular hemodynamics in various physiological and pathological ...whether endothelium-derived relaxing ...
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The Possible Involvement of Nitric Oxide/Endothelium Derived Relaxing Factor in Atropine-Induced Vasorelaxation
... of endothelium derived relaxing factor (EDRF) at large ...without endothelium intact in the absence and presence of nitric oxide synthase inhibitors, N-omega nitro-L-arginine methyl ...
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The G proteins of the G alpha i and G alpha q family couple the bradykinin receptor to the release of endothelium derived relaxing factor
... endothelium-derived relaxing factor (EDRF). Little is known, however, regarding the identity of the G protein(s) involved. Here we demonstrate that G proteins of the G alpha i and G alpha q ...
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NO forms an adduct with serum albumin that has endothelium derived relaxing factor like properties
... The data presented here extend these observations to an in vivo model and demonstrate that BSA can combine with NO probably as NO', the nitrosonium ion to form S-nitroso-BSA that possese[r] ...
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Endothelium derived relaxing factor/nitric oxide modulates angiotensin II action in the isolated microperfused rabbit afferent but not efferent arteriole
... Change in luminal diameter induced by L-NAME, which inhibits synthesis of EDNO, in microperfused afferent arterioles Af-Art and efferent arterioles studied with orthograde EfArt- OP or r[r] ...
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Reduced capacity of tumour blood vessels to produce endothelium-derived relaxing factor: Significance for blood flow modification
... Capacity for EDRF production may represent a difference between tumour and normal tissue blood vessels, which could be exploited for selective pharmacological manipulation of tumour bloo[r] ...
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Role of endothelium derived nitric oxide in the bleeding tendency of uremia
... Endothelium-derived relaxing factor, now identified as nitric oxide (NO), is a labile humoral agent formed by vascular endothelial cells from ...induce endothelium-dependent relaxation ...
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Inhibition of neointimal proliferation in rabbits after vascular injury by a single treatment with a protein adduct of nitric oxide
... Endothelium-derived relaxing factor is important for vascular homeostasis and possesses qualities that may modulate vascular injury, including vasodilation, platelet inhibition, and inhibition ...
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Inactivation of endothelial derived relaxing factor by oxidized lipoproteins
... The present results with cultured endothelial cells suggest that oxidized lipoproteins inhibit endothelium-dependent vascular relaxation by inactivation of EDRF after its release from en[r] ...
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Endothelium derived Toll like receptor 4 is the key molecule in LPS induced neutrophil sequestration into lungs
... The rapid and selective accumulation of neutrophils into the lungs is thought to underlie the pulmonary failure that leads to sepsis-related death. In this study we investigated whether neutrophil TLR4 is important in ...
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Direct evidence for the importance of endothelium derived nitric oxide in vascular remodeling
... compromised endothelium-dependent relax- ations to endothelium-dependent vasodilators ...of endothelium-derived ...growth factor- b (TGF- b ) or counteract the actions of known smooth ...
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Nitric oxide and angiotensin II Glomerular and tubular interaction in the rat
... Two different groups have recently shown that endothelialderived relaxing factor or nitric oxide NO is involved not only in the regulation of basal renal hemodynamics but also in the ren[r] ...
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<p>Exercise restores impaired endothelium-derived hyperpolarizing factor–mediated vasodilation in aged rat aortic arteries via the TRPV4-K<sub>Ca</sub>2.3 signaling complex</p>
... GSK1016790A-induced endothelium-derived hyperpolarizing factor (EDHF) response in rat aortic ...arteries derived from rats in the Young, Old, and Old + ET ...
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Identification of Pigment Epithelium-Derived Factor as an Adipocyte-Derived Inflammatory Factor
... Recombinant human PEDF was ob- tained from Millipore (Billerica, MA, USA). The endotoxin content was below the level of detection with a Limulus assay. Bromoenol lactone (BEL) was pur- chased from Caymen Chemical (Ann ...
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