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Energy Homeostasis

Energy homeostasis targets chromosomal reconfiguration of the human GH1 locus

Energy homeostasis targets chromosomal reconfiguration of the human GH1 locus

... that energy homeostasis alters postnatal hGH synthesis through dynamic changes in the 3-dimensional chromatin structure of the GH1 locus, including structures required for cell type specificity during ...

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Energy Homeostasis Control in Drosophila Adipokinetic Hormone Mutants

Energy Homeostasis Control in Drosophila Adipokinetic Hormone Mutants

... of energy stores is evolutionarily conserved among insects (reviewed in Gäde and Auerswald 2003; Lorenz and Gäde ...in energy homeostasis, or rather reveal the existence of distinct AKH-regulated ...

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Incorporating genome-scale tools for studying energy homeostasis

Incorporating genome-scale tools for studying energy homeostasis

... DNA microarrays provide an efficient route to finding gene targets involved in quantitative traits and biological processes associated with complex phenotypes, such as energy homeostasis. The core concept ...

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CD8+ T cells in beige adipogenesis and energy homeostasis

CD8+ T cells in beige adipogenesis and energy homeostasis

... steatohepatitis and the associated hepatic carcinogenesis (32). Our findings also support the hypothesis that aggressive immunotherapies, for instance, employed in malignant and inflammatory disease, may substan- tially ...

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The impact of epidermal growth factor receptor inhibition on energy homeostasis

The impact of epidermal growth factor receptor inhibition on energy homeostasis

... with suppressed EGFR signaling to further delineate the role of EGFR in diet-induced obesity. Wild-type C57BL/6J mice were chronically exposed to a high-fat western diet with or without a small molecule inhibitor to the ...

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The Role Of Protein Tyrosine Phosphatase 1b In The Central Regulation Of Energy Homeostasis

The Role Of Protein Tyrosine Phosphatase 1b In The Central Regulation Of Energy Homeostasis

... of energy balance, and these pathways are also candidates of PTP1B ...of energy balance within leptin receptor-expressing cells and within the hypothalamus specifically, and further begin to unravel the ...

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TEAD4 establishes the energy homeostasis essential for blastocoel formation

TEAD4 establishes the energy homeostasis essential for blastocoel formation

... blastocoel, express TE-associated genes and produce trophoblast giant cells. Therefore, TEAD4 is not essential for specifying the TE lineage. It is, however, essential for blastocoel formation and expansion, but only ...

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Energy Homeostasis by the Peripheral Serotonergic System

Energy Homeostasis by the Peripheral Serotonergic System

... of energy homeostasis by means of stimulating several organs but especially pancreatic β cells, the liver, white adipose tissue, brown adipose tissue, and the skeletal ...regulates energy ...

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The gliotransmitter ACBP controls feeding and energy homeostasis via the melanocortin system

The gliotransmitter ACBP controls feeding and energy homeostasis via the melanocortin system

... of energy sufficiency including leptin and insulin, arcuate POMC neurons release α-melanocyte– stimulating hormone that activates the melanocortin-4 receptor (MC4R) and downstream anorectic and catabolic responses ...

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The role of Fyn kinase in CRH regulation of energy homeostasis

The role of Fyn kinase in CRH regulation of energy homeostasis

... metabolism, energy homeostasis, gastrointestinal and immune systems, have been mediated via activation of the CRH receptors ...differential energy needs drive different phosphorylation events, is ...

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Brain fatty acid synthase activates PPARα to maintain energy homeostasis

Brain fatty acid synthase activates PPARα to maintain energy homeostasis

... of energy balance affects susceptibility to obesity and diabetes, but how fatty acids, malonyl-CoA, and other metabolites act at this site to alter metabolism is poorly ...

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Ghrelin Regulates Energy Homeostasis Through Discrete Central and Peripheral Signaling Mechanisms

Ghrelin Regulates Energy Homeostasis Through Discrete Central and Peripheral Signaling Mechanisms

... While BOLD response to reciprocated feedback was similar between groups, aMCC was significantly elevated in high anxiety comparison to low anxiety subjects when processing unreciprocated[r] ...

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Disruption of histidine and energy homeostasis in chronic obstructive pulmonary disease

<p>Disruption of histidine and energy homeostasis in chronic obstructive pulmonary disease</p>

... high energy demand such as skeletal ...an energy shuttle between the sites of ATP synthesis and ...providing energy and preventing skeletal muscle atrophy, 31,32 it is plausible that their reduced ...

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Energy homeostasis : crosstalk between adipose tissue and the human hypothalamus

Energy homeostasis : crosstalk between adipose tissue and the human hypothalamus

... Papers: K Kos, AL Harte, A Tonchev, G Chaldakov, S James, D Snead, JP O'Hare, PG McTernan, S Kumar 2007 Adiponectin and resistin in central regulation of human energy metabolism: express[r] ...

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Adipose tissue derived factors in obesity, inflammation & energy homeostasis

Adipose tissue derived factors in obesity, inflammation & energy homeostasis

... McTernan, and insulin by diabetes: 2 and Resistin and type regulation of resistin expression lipid metabolism the glucose and effects on of and recombinant resistin rosiglitazone in huma[r] ...

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Energy homeostasis in monotremes

Energy homeostasis in monotremes

... The fitness benefits must be considerable for short-beaked echidnas, because the species seems to be specialized to minimize energy expenditure, and many aspects of their ecology and behavior are correlated with ...

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Ghrelin Regulates Energy Homeostasis Through Discrete Central and Peripheral Signaling Mechanisms

Ghrelin Regulates Energy Homeostasis Through Discrete Central and Peripheral Signaling Mechanisms

... Further, while popular discourse offers examples of a growing awareness in birth culture of the need to address disparities in outcomes and practice evidencebasedbirth.com 2017; https://[r] ...

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Central insulin action in energy and glucose homeostasis

Central insulin action in energy and glucose homeostasis

... Insulin has pleiotropic biological effects in virtually all tissues. However, the relevance of insulin signaling in peripheral tissues has been studied far more extensively than its role in the brain. An evolving body of ...

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Sex differences in metabolic homeostasis, diabetes, and obesity

Sex differences in metabolic homeostasis, diabetes, and obesity

... Until recently, most clinical research has been carried out under the assumption that the male can fulfill the function of the representative of the human species. Today, basic research using animal models is still ...

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Serotonin 2C receptors in pro opiomelanocortin neurons regulate energy and glucose homeostasis

Serotonin 2C receptors in pro opiomelanocortin neurons regulate energy and glucose homeostasis

... Pharmacological compounds that target central serotonin (5-hydroxytryptamine [5-HT]) signaling potently regulate energy homeostasis and have been used effectively as antiobesity drugs in humans (1). A prime ...

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