enhanced bioavailability
Pharmacokinetic Study of Nanoparticulate Curcumin: Oral Formulation for Enhanced Bioavailability
... poor bioavailability and rapid ...oral bioavailability, biological activity or tissue-targeting ability of ...on bioavailability in Male Wistar rats at a dose of 100 mg curcumin/kg body weight and ...
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Galactosylated PLGA nanoparticles for the oral delivery of resveratrol: enhanced bioavailability and in vitro anti-inflammatory activity
... oral bioavailability of RES after ...RES. Enhanced bioavailability and bioactivity for RES-GNPs is demonstrated to be concerned with galactosylation of NPs that renders them superior transepithelial ...
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Enhanced Bioavailability and Anticancer Effect of Curcumin Loaded Electrospun Nanofiber: In Vitro and In Vivo Study
... group was slightly quicker than that in the pure CUR group but visibly faster than that in the CUR@PVP group (Fig. 7a). Figure 7b revealed that the CUR@PVP group displayed much higher effi- ciency in inhibiting tumor ...
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Design and development of fast mouth dissolving tablet of telmisartan for enhanced bioavailability
... development of new drug. Delivery systems for already existing drugs, with enhanced efficacy and bioavailability, thus reducing the dose and dosing frequency to minimize the side effects. The aim of a ...
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Formulation and Evaluation of Mouth Dissolving Tablets of Dicyclomine HCl with Enhanced Bioavailability
... cases, bioavailability of drug is significantly greater than those observed from conventional tablet dosage form Mouth-dissolving drug delivery systems have rapidly gained acceptance as an important new way of ...
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ENHANCED BIOAVAILABILITY OF DRUGS VIA INTRANASAL DRUG DELIVEY SYSTEM
... liver and pre-systemic elimination in the GI tract is avoided. Nasal drug delivery has great potential to treat both chronic and acute disease. One of the most important factors hindering the quality of nasal product is ...
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Enhanced bioavailability of apigenin via preparation of a carbon nanopowder solid dispersion
... In this study, a novel SD formulation of AP for oral admin- istration was prepared using CNP. The results demonstrated that CNP-based SD was a successful strategy to improve the dissolution behavior and oral ...
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PREPARATION AND EVALUATION OF ARTEMISININFREEZEDRIED POWDERS WITH ENHANCED BIOAVAILABILITY
... oral bioavailability of artemisinin, a poorly water-soluble ...Relative bioavailability studies were conducted in Sprague-Dawely rats using the optimized formulation against the reference ...
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FORMULATION AND EVALUATION OF NANOEMULSION FOR ENHANCED BIOAVAILABILITY OF ITRACONAZOLE
... ABSTRACT: Nanoemulsions are the novel drug delivery system which allows sustained or controlled release of drug, biological active ingredient and genetic material. Nanoemulsion is a system consisting of oil, surfactant ...
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Enhanced bioavailability and anthelmintic efficacy of mebendazole in redispersible microparticles with low-substituted hydroxypropylcellulose
... T max (time taken to achieve C max ) and C max (maximum plasma concentration) were estimated as the mean values of T max for the six mice used per group and time interval with the highest MBZ plasma concentration for ...
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Oral Delivery of ascorbic acid stabilized rifampicin nanoparticles for enhanced bioavailability of rifampicin.
... nanoparticles 118 . Glucose and lactose were evaluated as cryo- and lyo protectants for the L- PLA nanoparticles because these nanoparticles could not survive during the drying process without protectants. Even the ...
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Recent trends in the development of nanophytobioactive compounds and delivery systems for their possible role in reducing oxidative stress in Parkinson’s disease models
... show enhanced benefits in cell and animal models of ...limits bioavailability, stability, and dissolution at target sites in the ...showed enhanced bioavailability in the rat ...their ...
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QUALITATIVE ANALYSIS AND QUANTITATIVE DETERMINATION OF “CURCUMIN” IN A SIDDHA HERBO MINERAL FORMULATION USING HIGH PERFORMANCE THIN LAYER CHROMATOGRAPHY (HPTLC)
... poor bioavailability. [18] Despite the lower bioavailability, therapeutic efficacy of curcumin against various human diseases including cancer, cardiovascular diseases, diabetes, arthritis, neurological ...
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‘‘OPPORTUNITIES AND CHALLENGES IN RECENT TRENDS IN HERBAL MEDICINES’’
... to enhanced bioavailability, reduced toxicity, sustained release action, protection from GI degradation which cannot be obtained through conventional drug delivery system due to large molecular size, poor ...
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PHYTOSOME A NOVEL APPROACH FOR HERBAL DRUG DELIVERY
... Enhanced bioavailability: Many researches done which shows improved absorption and bioavailability with phytosomes in comparison to the conventional ...
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Nanodrugs: pharmacokinetics and safety
... offer enhanced bioavailability of orally taken drugs, prolonged half-life of injected drugs (by reducing immunogenicity), and targeted delivery to specific ...
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Utility of Sulfobutyl Ether beta-Cyclodextrin Inclusion Complexes in Drug Delivery: A Review
... Liposomes have enhanced permeability and retention effects. They can be used for targeted delivery of the drugs that directly reach the site of action and show improved therapeutic activity. In a study, liposomal ...
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SOLID DISPERSION TECHNOLOGY: RECENT ADVANCEMENTS IN THE DELIVERY OF VARIOUS PHYTOCONSTITUENTS
... The enhanced and effective dissolution rate of various drugs from prepared solid dispersions is based on different mechanisms described in the following ...the bioavailability of poorly soluble drugs by ...
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Enhanced transdermal bioavailability of testosterone propionate via surfactant-modified ethosomes
... The results of the analysis of the blood samples show that C max and AUC values for the ethosomal system were signifi- cantly higher (P , 0.05) compared with the TP liposomes. In the pharmacokinetic experiments, the ...
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Self Nano Emulsifying Drug Delivery Systems for Oral Delivery of Hydrophobic Drugs
... Most of the drugs which are recently discovered are poorly water soluble and the oral delivery of these drugs have become a major problem. Drugs of Class II or IV, as per Biopharmaceutical classification system (BCS) ...
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