Enteroendocrine cell (EEC)
Generation of enteroendocrine cell diversity in midgut stem cell lineages
... endocrine cell subtypes not yet fully ...governing enteroendocrine cell ...that cell diversity is seen at two distinct levels: regional and ...II enteroendocrine cells can be ...
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The novel enterochromaffin marker Lmx1a regulates serotonin biosynthesis in enteroendocrine cell lineages downstream of Nkx2 2
... the enteroendocrine progenitor marker Ngn3 was not changed in the duodenum or colon of ...in enteroendocrine hormone expression is due to a loss of enteroendocrine progenitor cells or of the upstream ...
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Short chain fatty acid level and field cancerization show opposing associations with enteroendocrine cell number and neuropilin expression in patients with colorectal adenoma
... of EEC, and this expression appears related to butyrate levels, in agree- ment with the hypothesis raised from our in vitro ...from EEC-like patterns in adenomatous tissue, implying an early and potential ...
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Human enteroendocrine cell responses to infection with Chlamydia trachomatis: a microarray study
... influence EEC function. We stud- ied the response pattern of enteroendocrine cells to intracellular bacteria in vitro using ...on EEC function but we cannot deter- mine if our findings are Chlamydia ...
12
Drosophila Atg16 promotes enteroendocrine cell differentiation via regulation of intestinal Slit/Robo signaling
... Inflammatory bowel diseases (IBDs) are chronic inflammatory disorders of the gastrointestinal tract. The most common IBD forms are Crohn ’ s disease (CD) and ulcerative colitis. Lifestyle and environment strongly ...
12
Ttk69 acts as a master repressor of enteroendocrine cell specification in Drosophila intestinal stem cell lineages
... EE cell differentiation is mediated by the acheate-scute complex (AS-C) proneural genes, which include the homologous genes achaete (ac), scute (sc), lethal of scute [l ’ sc, or l(1)sc] and asense (ase), which are ...
11
Loss of enteroendocrine cells in mice alters lipid absorption and glucose homeostasis and impairs postnatal survival
... endocrine cell lineage in the developing pancreas (11) and intestine (12, ...any enteroendocrine and pancreatic endocrine cells, and mice show severe diabetes and die shortly after birth (11, ...endocrine ...
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The role of Hes genes in intestinal development, homeostasis and tumor formation
... from cell to cell (Wilson and Radtke, 2006; Kageyama et ...regulates enteroendocrine cell development (Yang et ...secretory cell development by repressing Math1 and Ngn3 ...
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Neuroepithelial circuit formed by innervation of sensory enteroendocrine cells
... vesicles, enteroendocrine cells also have small clear synaptic vesicles (19), suggest- ing that enteroendocrine cells have an essential organelle for neurotrans- ...the enteroendocrine ...
6
Abnormalities in ileal stem, neurogenin 3, and enteroendocrine cells in patients with irritable bowel syndrome
... that enteroendocrine cell can ex- press two hormones, such as glucagon-like peptide-1 and GIP in the small intestine, and PYY and oxyntomo- dulin in the distal small and large intestines ...mature ...
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A xenogeneic-free system generating functional human gut organoids from pluripotent stem cells
... Paneth cell–specific protein, defensin α-6 (DEFA6) (Figure 3A), and were shown to contain secretory granules by TEM (Figure ...epithelial enteroendocrine cell marker, was lower in gut organoids than ...
14
Potential roles of GPR120 and its agonists in the management of diabetes
... Clara cell 10-kDa protein; GOC, gastric oxyntic cell; TBC, taste bud cell; TRPM5, transient receptor potential channel type M5; CD36, cluster of differentiation 36; GLP-1, glucagon-like peptide-1; ...
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Enteroendocrine cells sensory sentinels of the intestinal environment and orchestrators of mucosal immunity
... in eec number 171, 172 as well as peptide granule storage 130 ...5-HT+ cell increases are thought to prolong inflammation via increased IFN-y in tissue samples of refractory celiac patients 174 , again ...
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The Hes gene family: repressors and oscillators that orchestrate embryogenesis
... Misexpression of Hes1 or Hes5 in the developing mouse brain at embryonic day (E) 13.5 inhibits neuronal differentiation and maintains a radial glial cell identity (Fig. 2B) (Ohtsuka et al., 2001). In the absence ...
9
Chlamydia trachomatis antigens in enteroendocrine cells and macrophages of the small bowel in patients with severe irritable bowel syndrome
... IBS. Enteroendocrine cells play a pivotal role in the control of gut motility and secretion and increased numbers of enteroendocrine cells have been detected in patients that developed IBS after an acute ...
9
Proposal for a European Parliament and Council Directive amending Council Directives 76/116/EEC, 80/876/EEC, 89/284/EEC and 89/530/EEC on the approximation of the laws of the Member States relating to fertilizers. COM (96) 594 final, 21 November 1996.
... Proposal for a European Parliament and Council Directive amending Council Directives 76/116/EEC, 80/876/EEC, 89/284/EEC and 89/530/EEC on the approximation of the laws of the Member Stat[r] ...
10
"Social Europe: Still binding regulations?"
... The history of European social policy is more a story of failure than great success Nevertheless since the beginning of the European Community at least five different attempts each with their own priorities, underlying ...
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Proposal for a Directive of the European Parliament and of the Council amending Council Directives 85/611/EEC, 92/49/EEC, 92/96/EEC and 93/22/EEC as regards exchange of information with third countries (presented by the Commission). COM (99) 748 final, 10 January 2000
... Provisions similar to those amended by Article 1 of Directive 98/33/EC exist in other Directives relevant to the financial system: Investment Services Directive (93/22/EEC); UCITS Directive (85/611/EEC), ...
6
1992-1993 Report on the progress achieved in implementing POSEIMA. Report presented by the Commission to the Council and European Parliament in accordance with Section VI of POSEIMA and Article 35 of (EEC) Regulation 1600/92. COM (94) 476 final, 9 December 1994
... Common implementing rules Commission Regulation EEC No 2596/93 of 22 September 1993 amending Regulations EEC No 131/92, EEC No 1695/92 and EEC No 1696/92 concerning common detailed rules[r] ...
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Communication from the Commission: state of the environment in the 6 Länder of the former East Germany. COM (98) 33 final, 2 February 1998
... Water a Article 1 of Directive 90/656/EEC: Surface water Directives 75/440/EEC and 79/869/EEC According to Article 1 of Directive 90/656/EEC Germany had to ensure, in respect of the terr[r] ...
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