Epithelial membrane protein-1
The Epstein-Barr virus latent membrane protein 1 regulates gene expression by engaging multiple signaling pathways
... Similar to EBNA2 and EBNA-LP, EBNA3s are only expressed in type III latency of EBV infections. In vitro infections using recombinant EBV have shown that EBNA3A and EBNA3C are essential for EBV-mediated B cell ...
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The cAMP responsive element binding protein 1 transactivates epithelial membrane protein 2, a potential tumor suppressor in the urinary bladder urothelial carcinoma
... Alternatively, membrane-associated tyrosine/threonine 1 protein (PKMYT1) is a dual- specificity kinase that can phosphorylate both sites [42, 43], with a propensity toward Y14 ...activation ...
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Epstein-Barr Virus Latent Membrane Protein 1 Represses DNA Repair through the PI3K/Akt/FOXO3a Pathway in Human Epithelial Cells
... Latent membrane protein 1 (LMP1), an Epstein-Barr virus (EBV) oncoprotein, mimics a constitutively activated tumor necrosis factor receptor and activates various signaling pathways, including ...
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Cytosolic phospholipase A2 regulates Golgi structure and modulates intracellular trafficking of membrane proteins
... of epithelial cells derives from the selective distribution of their plasma-membrane proteins and lipids into distinct plasma-membrane domains (1, ...Intracellular protein traffic from ...
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Wnt signaling regulates trans-differentiation of stem cell like type 2 alveolar epithelial cells to type 1 epithelial cells
... a membrane bound O-acyltransferase (MBOAT) involved in the acylation and secretion of Wnt proteins ...ITGAV protein levels have, how- ever, demonstrated that Wnt5a can cell type specifically modify ITGAV ...
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Epstein-Barr Virus Downregulates MicroRNA 203 through the Oncoprotein Latent Membrane Protein 1: a Contribution to Increased Tumor Incidence in Epithelial Cells
... EBV-infected epithelial cells and EBV-associated NPC, and this occurs dur- ing the early stages of EBV ...onco- protein LMP1 was the essential viral factor responsible for miR-203 ...to epithelial ...
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Epstein-Barr Virus Represses the FoxO1 Transcription Factor through Latent Membrane Protein 1 and Latent Membrane Protein 2A
... Epstein-Barr virus (EBV) is a member of the human ␥ -her- pesvirus family. Greater than 90% of the adult population worldwide is infected with the virus. In the majority of cases, EBV infection is asymptomatic for the ...
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Epstein-Barr Virus Latent Membrane Protein 1 Induces Cancer Stem/Progenitor-Like Cells in Nasopharyngeal Epithelial Cell Lines
... sopharyngeal epithelial cells with or without LMP1 expression ... 1 integrin), CD49b ( ␣ 2 integrin), and CD49f ( ␣ 6 integrin), was also upregulated by LMP1 expression ...
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Localization of cystic fibrosis transmembrane conductance regulator in chloride secretory epithelia
... the protein: the R (regulatory) domain (M13-1), the COOH terminus (M1-4), and a predicted extracellular domain ...used epithelial cell lines that express endogenous CFTR and have a cAMP-activated ...
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Epithelial Cell Adhesion to Extracellular Matrix Proteins Induces Tyrosine Phosphorylation of the Epstein-Barr Virus Latent Membrane Protein 2: a Role for C-Terminal Src Kinase
... an epithelial malignancy (25, 38–41, ...(EBNAs 1 through 6), EBERs, BamHI A transcripts, and three latent membrane proteins, LMP1, LMP2A, and LMP2B, are ...
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Epithelial membrane protein 2 governs transepithelial migration of neutrophils into the airspace
... caveolar protein HER2, whose cell-surface levels are reportedly reduced by caveolin-1 overexpression and stabilized by caveolin-1 silencing ...EMP2-null epithelial cells is consistent with ...
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Exploring the immunomodulatory potential of microbial associated molecular patterns derived from the enteric bacterial microbiota
... Vibrio cholerae O395 outer membrane vesicles modulate intestinal epithelial cells in a NOD1 protein-dependent manner and induce dendritic cell-mediated Th2/Th17 cell responses. Chromosom[r] ...
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Natural selection and genetic diversity of domain I of Plasmodium falciparum apical membrane antigen 1 on Bioko Island
... To assess the association between host immune pres- sure and natural selection of PfAMA-1, genetic polymor- phisms in predicted B-cell epitopes and IUR regions were analysed. Based on a recent report, detailed ...
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An ITAM in a Non-enveloped Virus (Reovirus) Regulates Activation of NF-kB, Induction of Interferon-ß, and Viral Spread.
... for 1 h, supplemented with media, and then incubated as ...(Promega), 1 mM dithiothreitol (Promega), 1 mM each deoxynucleoside triphosphate (Roche), ...
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Membrane Binding of HIV-1 Matrix Protein: Dependence on Bilayer Composition and Protein Lipidation
... the protein or with the environ- ment of PS in the cell membrane which could lead to its enrich- ment through cosorting with raft-related ...the protein load was only marginally re- duced (compare ...
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Genetic diversity of vaccine candidate antigens in Plasmodium falciparum isolates from the Amazon basin of Peru
... Results also showed two non-synonymous substitutions in R1 and R2 regions of Pfama-1. The extensive number of non-synonymous polymorphisms outside R1 and R2 described in this study revealed that this gene could ...
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Lu, Aiping (2008): Development of proteomics techniques for individual protein and membrane protein mapping. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... Dynamic range and sensitivity are two critical issues related to MS-based proteomics. Real biological samples, even the peptide digested from the same protein, can display a dynamic range of several thousand to ...
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Mapping and Characterization of the N-Terminal I Domain of Human Immunodeficiency Virus Type 1 Pr55Gag
... fusion protein to sediment in the detergent-resistant pellet [as shown by a com- parison of the results for GAG384/GFP and GAG384(R380, 384A)/GFP ...fusion protein found in the detergent-resistant pellet ...
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A Membrane Leucine Heptad Contributes to Trafficking, Signaling, and Transformation by Latent Membrane Protein 1
... two membrane-spanning domains of LMP1 or LZ1 tagged with either GFP or mRFP (termed wt 1-2TM and LZ1 1-2TM) because they were suffi- cient for targeting to lipid rafts (6, ...Wt 1-2TM and LZ1 ...
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Characterization of Two Putative Protein Translocation Components in the Apicoplast of Plasmodium falciparum
... PfTic22 protein, which is con- sistent with retention of the native promoter during integration of the tag ...with protein amounts peaking at approximately 24 to 28 h, the early- to mid-tropho- zoite stage ...
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