Epithelial polarity
Laminin is required to orient epithelial polarity in the C elegans pharynx
... coordinating epithelial polarity (Urbano et ...a polarity signal in only certain epithelia, such as the pharynx, or might function redundantly with other signals such as other basement membrane ...
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TBX1 regulates epithelial polarity and dynamic basal filopodia in the second heart field
... including epithelial polarity, cell shape and cell dynamics, remain poorly ...the epithelial properties of SHF ...that epithelial and progenitor cell status are coupled in the SHF, identifying ...
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Tissue specific function of Patj in regulating the Crumbs complex and epithelial polarity
... ectoderm polarity and embryonic development, whereas more severe defects are observed in the adult follicular epithelium, including mislocalisation of the Crumbs complex from the apical domain, as well as ...
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Connecting epithelial polarity, proliferation and cancer in Drosophila: the many faces of lgl loss of function
... cell polarity is a prominent feature of epithelial ...apical-basal polarity suggest- ing that a link exists between disruption of epithelial polarity and the control of cell ...larval ...
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Disorganized epithelial polarity and excess trophectoderm cell fate in preimplantation embryos lacking E cadherin
... We found a significant increase in the proportion of cells with membrane enrichment of the apical protein PKC and a paucity of PKC in the cytoplasm in E-cadherin mutants. In wild-type embryos, 64% of cells had ...
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Ischemia induced loss of epithelial polarity Role of the tight junction
... In proximal tubular cells ischemia is known to result in the redistribution of apical and basolateral domain-specific lipids and proteins into the alternate surface membrane domain.. Sin[r] ...
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A Fasciclin 2 morphogenetic switch organizes epithelial cell cluster polarity and motility
... global polarity of the cluster, as the orientation of delamination, mediated by the BCs, directly correlates with Fas2 polarity in PCs ...of epithelial cluster polarity during delamination and ...
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PAR 3 is required for epithelial cell polarity in the distal spermatheca of C elegans
... epithelial polarity in flies and mammals (Izumi et ...in epithelial polarity in ...in epithelial development are masked by persistence of wild- type maternal mRNA and protein in ...
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HNF1B controls epithelial organization and cell polarity during ureteric bud branching and collecting duct morphogenesis
... early defects of cell polarity observed in Hnf1b mutants affect cilia maintenance. Moreover, neither the water channel AQP2 nor the lectin DBA could be detected in mutants, and the transcript levels of specific ...
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TTC7A mutations disrupt intestinal epithelial apicobasal polarity
... disrupt epithelial polarity in cell-based models ...study polarity markers in organoids after withdrawal of ...the polarity (Figure 5, ...
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Genetic studies define MAGUK proteins as regulators of epithelial cell polarity
... apico-basal polarity, cell adhesion, targeting of proteins to the plasma membrane, retention and clustering of receptors and polarizing signalling ...polarized epithelial phenotype can result in ...
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A common framework for EMT and collective cell migration
... of epithelial cells and tissues should be expanded to include different characteristic states of epithelial function and behaviour has previously been proposed by researchers studying mammary branching ...
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Cell polarity: models and mechanisms from yeast, worms and flies
... maintaining epithelial polarity (Müller and Wieschaus, 1996; Tepass, 1996; Pellikka et ...for polarity establishment (Müller and Wieschaus, 1996; Schober et ...
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Human Coronavirus 229E Infects Polarized Airway Epithelia from the Apical Surface
... Polarity of release of HCoV-229E in airway epithelia. Polar- ity of virus release from airway epithelial cells may determine whether a virus will spread systemically or remain in the respi- ratory tract. ...
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Balaji, Ramya (2018): Regulation of tensile stress in response to external forces coordinates epithelial cell shape transitions with organ growth and elongation. Dissertation, LMU München: Fakultät für Biologie
... This approach is used to generate mosaic tissues with homozygous mutant cells and heterozygous cells which are aphenotypic. It is based on a site-specific (FRT recombination target sites) mitotic recombination induced by ...
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DLG5 in Cell Polarity Maintenance and Cancer Development
... The component of the PAR complex, aPKC, is apically localized and participates in maintenance of apical-lateral polarity. aPKC can recruit the PAR3-PAR6 complex from tight junction sites to subapical region; as a ...
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A conserved function for Strabismus in establishing planar cell polarity in the ciliated ectoderm during cnidarian larval development
... of polarity between neighbouring cells, commonly requires a set of core PCP proteins: the transmembrane proteins Flamingo (Fmi), Frizzled (Fz) and Strabismus/Van Gogh (Stbm/Vang), and their cytoplasmic partners ...
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Lethal (2) Giant Larvae: An Indispensable Regulator of Cell Polarity and Cancer Development
... to epithelial tran- sition (MET) ...of polarity, proliferation and morphol- ogy of human mammary epithelial cells ...gastric epithelial dysplasia and gastric adenocarcinoma as well as ...
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Loss of LKB1 disrupts breast epithelial cell polarity and promotes breast cancer metastasis and invasion
... embryonic polarity by regulating activities of anillin family scaffold proteins ...posterior polarity and apical-basal ...cell polarity in ...axon/dendrite polarity by activating SAD/MAPK ...
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Review of effect of input parameters on output parameters of electrical discharge machining
... The material removal rate is increase with the increase in current value, duty factor and pulse on time. The review is also shows that copper tool electrode gives higher material removal rate due to the high thermal ...
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