EPO - Erythropoietin
Erythropoietin (EPO) in acute kidney injury
... human EPO (rHuEPO) is commer- cially available and is widely used for the treatment of ...of EPO have become apparent, in particular for ...supporting EPO as a general tissue protective drug and ...
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Original Article Antioxidant capacities of long-range cultured neurons enhanced by erythropoietin (EPO)-regulated Nrf2 pathway
... that erythropoietin (EPO) could enhance the body’s free radical scavenging abilities, thus exhibiting protective effects towards a variety of brain injuries, it was even considered that “EPO had ...
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Erythropoietin (EPO) Increases Myelin Gene Expression in CG4 Oligodendrocyte Cells through the Classical EPO Receptor
... where EPO decreases disease severity. EPO also promotes neurogenesis and is protective in models of toxic ...whether EPO could promote neurorepair by also inducing ...of EPO could be mediated ...
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Huh 7 cell line as an alternative cultural model for the production of human like erythropoietin (EPO)
... Aims: Erythropoietin (EPO) is a glycoprotein hormone which is required to regulate the production of red blood ...of EPO is known to cause anemia in chronically infected renal patients and they ...
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ERYTHROPOIETIN (EPO): ROLE IN NEUROPROTECTION/ NEUROREGENRATION AND COGNITION
... of erythropoietin (EPO), an endogenous hematopoietic growth factor, leaded to the new therapeutic avenues in the treatment of brain ...diseases. EPO has direct effects on cells of the nervous system ...
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Erythropoietin (EPO)-receptor signaling induces cell death of primary myeloma cells in vitro
... [1]. Erythropoietin/erythropoietin-receptor (EPO/EPOR) signaling is the main regulator of proliferation in the erythroid lineage ...The EPO/EPOR interaction initiates a signaling cascade that ...
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The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways
... B4; EPO: Erythropoietin; ERK1/2: Extracellular signal-regulated protein kinases 1 and 2; FACS: Fluorescence-activated cell sorting; FBS: Fetal bovine serum; FGF2: Fibroblast growth factor 2; FITC: ...
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Ergocalciferol treatment does Not improve erythropoietin utilization and hospitalization rate in hemodialysis patients
... Ergocalciferol; EPO: Erythropoietin; ESA: Erythropoietin simulating agents; ESRD: End-stage renal disease; HD: Hemodialysis; iPTH: intact parathyroid hormone; IQR: Interquartile ranges; KDIGO: Kidney ...
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Neurogenic inflammation after traumatic brain injury and its potentiation of classical inflammation
... AMT: Absorptive-mediated transcytosis; BBB: Blood-brain barrier; CNS: Central nervous system; EPO: Erythropoietin; RMT: Receptor-mediated transcytosis; SP: Substance P; TLR: Toll-like re[r] ...
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Erythropoiesis: insights into pathophysiology and treatments in 2017
... break; EPO: Erythropoietin; EPO-R: Erythropoietin receptor; ERFE: Erythroferrone; GvHD: Graft-versus-host disease; HAMP: Hepcidin antimicrobial peptide; HbE β 0: Hemoglobin E/ β -thalassemia; ...
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Heterozygous connexin 50 mutation affects metabolic syndrome attributes in spontaneously hypertensive rat
... EPO: Erythropoietin; G-CSF: Granulocyte-colony stimulating factor; GIP: Gastric inhibitory peptide; Gja8 gene: Gap junction protein, alpha 8 coding for connexin50 gene; GJD2 gene: Gap junction protein, ...
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Overexpression of sPRDM16 coupled with loss of p53 induces myeloid leukemias in mice
... Nonstandard abbreviations used: AML, acute myeloid leukemia; EPO, erythropoietin; Hb, hemoglobin; lin–, lineage negative; LTC-IC, long-term culture–initiating cell; MGG, May-Grünwald-Gie[r] ...
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Anemia in Elderly Koreans
... Serum EPO level is not increased sufficiently relative to the severity of the anemia, because of inflammatory cytokines.25 Our study of serum erythropoietin also revealed an inappropriat[r] ...
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Abstract
... of EPO that may be involved in the renoprotective effects observed in this ...enous EPO are still not completely understood, and only a few components have been identified or common pathways proposed [22, ...
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Erythropoietin mimics the acute phase response in critical illness
... of EPO has been identified in several studies ...human EPO is widely used as replacement therapy to treat the anaemia of chronic renal failure, and in pharmacological doses as a substitute for blood ...
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A meta-analysis and systematic review evaluating the use of erythropoietin in total hip and knee arthroplasty
... received EPO with those who did ...received EPO with those who received PABD. Eleven RCTs compared the effect of EPO plus PABD with PABD ...subgroups: EPO alone versus no EPO, ...
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Constitutively Active Soluble Form of Erythropoietin Receptor Suppresses Growth and Angiogenesis of Xenografts of Transfected Cancer Cell Lines
... of Epo in the cell lines before implan- tation and were comparable in both hosts implanted with transfected or wild-type ...Furthermore, Epo and EpoR mRNAs and receptors for 1A -adrenaline ( 1A - ...
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The Effects of Low Altitude Training on Erythropoietin Response and Hematological Variables in Elite Female Fencers
... training at low altitude is not sufficient to enhance blood oxygen-carrying capacity. It are in agreement with previous investigations of low altitude. Only one report we found which is not similar with our results. ...
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A case–control study of prevalence of anemia among patients with type 2 diabetes
... major factor in the anemia of malignancy. In fact, nu- merous in vitro studies have illustrated the central role of tumor necrosis factor-alpha (TNF-α) in the pathogen- esis of anemia [20]. Other cytokines, such as ...
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Unfolded protein response (UPR) integrated signaling networks determine cell fate during hypoxia
... Although activation of the UPR supports surviving hypoxia, it can also impair cellular survival [60]. The ER, for example, is responsible for folding and maturation of trans- membrane and secretory proteins [61–69] that ...
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