epoetin alfa
Comparable pharmacokinetics and pharmacodynamics of two epoetin alfa formulations Eporon<sup>®</sup> and Eprex<sup>®</sup> following a single subcutaneous administration in healthy male volunteers
... Subjects and methods: A randomized, double-blind, two-sequence, crossover study was conducted. Subjects were randomly assigned to receive a single dose, that is, 4,000 IU, of the test or comparator epoetin ...
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COST EFFECTIVENESS OF METHOXY POLYETHYLENE GLYCOLEPOETIN Β VERSUS EPOETIN ALFA IN THE TREATMENT OF HEMODIALYSIS PATIENTS WITH RENAL ANEMIA
... This study is a prospective single center randomized controlled open labeled clinical trial that was carried out at hemodialysis Unit, Baghdad Teaching Hospital from 1st October 2014 to 5th May 2015. Ethical Approval was ...
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Feasibility of a Multiplex Flow Cytometric Bead Immunoassay for Detection of Anti-Epoetin Alfa Antibodies
... with epoetin alfa that developed antibody-mediated pure red blood cell aplasia as a means to demonstrate the utility of this ...anti-epoetin alfa antibodies with a relative antibody ...
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Rituximab therapy for pure red cell aplasia due to anti epoetin antibodies in a woman treated with epoetin alfa: a case report
... A 65-year-old Asian-American woman was diagnosed with chronic hepatitis C (HCV), genotype 2 and was referred for treatment of her HCV infection. Abdominal imaging showed a nodular appearance of the liver and hypersplen- ...
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The importance of iron in long-term survival of maintenance hemodialysis patients treated with epoetin-alfa and intravenous iron: analysis of 9.5 years of prospectively collected data
... with epoetin-alfa (EPO) and newer erythrocyte stimulating agents (ESA) has mitigated its severity, some recent studies have reported adverse outcomes of effective anemia correction with EPO and other ESAs ...
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Erythropoiesis-stimulating agents for the treatment of chemotherapy-induced anemia: comparisons from real-world clinical experience
... biosimilar epoetin alfa appears to be as effective as darbepoetin once every 3 weeks for raising hemoglobin levels and avoiding the need for red blood cell ...
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Recombinant human epoetin beta in the treatment of chemotherapy-related anemia
... the epoetin and control ...the epoetin arm (HR ...between epoetin and control arms in the analysis of all 12 studies but a trend towards increased disease progression in 3 trials for which long term ...
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Novel Approaches in Erythropoietin
... Erythropoietin, or EPO, is a glycoprotein hormone that controls erythropoiesis, or red blood cell production. It is a cytokine for erythrocyte (red blood cell) precursors in the bone marrow. Also called hematopoietin or ...
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Biosimilar epoetin for the management of chemotherapy-induced anemia in elderly patients
... Inclusion criteria included patients at least 18 years of age presenting with CIA (irrespective of chemotherapy cycle) associated with solid tumors, lymphomas, or myelomas and eligible for treatment with an ...
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Hemoglobin Level Stability after a Switch from Darbepoetin Alfa to Epoetin Beta Pegol for the Treatment of Renal Anemia in Hemodialysis Patients
... Dalbepoetin alfa (DA) has a much longer half-life and longer erythropoietic effect than epoetin alfa [6] ...of epoetin alfa per 1 μg of DA ...
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A PROSPECTIVE AND OBSERVATIONAL STUDY OF USE AND FREQUENCY OF VARIOUS ERYTHROPOIETIN (EPO) CONGENERS AND ANALYSING THEIR EFFECTIVENESS IN THREE FORMS: DARBEPOETIN ALFA, EPOETIN ALPHA AND PEGYLATED ERYTHROPOIETIN ON DIALYSIS PATIENTS AT MAX SUPER SPECIALITY HOSPITAL, PATPARGANJ, DELHI
... Darbepoetin alfa, Epoetin alpha and Pegylated Erythropoietin, by calculating their hemoglobin level of the patient on ...Darbepoetin alfa (before and after 7.8 and 10.9), Epoetin alfa ...
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Switch from epoetin to darbepoetin alfa in hemodialysis: dose equivalence and hemoglobin stability
... from epoetin alfa to darbepoetin alfa in October 2007 (index date) who had been on hemodialysis for at least 15 months before the index date and remained on hemodialysis for at least 24 months after ...
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Profile of peginesatide and its potential for the treatment of anemia in adults with chronic kidney disease who are on dialysis
... as epoetin alfa given thrice weekly (dialysis patients) or darbepoetin given once weekly (nondialysis patients), in correcting anemia of chronic kidney disease as well as maintaining hemoglobin within the ...
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HX575: established biosimilarity in the treatment of renal anemia and 10 years of clinical experience
... 26. Zoccolo AM, Battiato S, Mauceri B, Milana F, Napoletano F, Barbera R. Switching from epoetin alfa and darbepoetin to biosimilar epoetin alfa in patients with CRI in the uraemic phase. ...
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An open-label, sequential, dose-finding study of peginesatide for the maintenance treatment of anemia in chronic hemodialysis patients
... from epoetin alfa to ...agents. Epoetin alfa-induced reti- culocytosis (the pharmacodynamic effect) peaks approxi- mately 1 to 2 weeks after administration [11], substantially beyond its ...
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4795.pdf
... 6/5/72, ALFA Papers Box 2 File 21) In the weeks that follow the appearance of this letter, the Bird issues are filled with discussions of gender, sexual orientation, and disagreements about how best to enact a ...
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Comparison of peginterferon alfa-2a and alfa-2b for treatment of patients with chronic hepatitis C:a retrospective study using the Japanese Interferon Database
... PEG-IFN alfa-2a and alfa-2b. Although a higher SVR rate was found for alfa-2a than for alfa-2b, the possibility of residual uncon- trolled confounding was acknowledged, such as details of the ...
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Effect of Blending Ratio of Fibers on the Properties of Nonwoven Fabrics Based of Alfa Fibers
... the Alfa fiber ratio in the ...the Alfa fiber ratio in the Alfa/PES, Alfa/Cotton and Alfa/Tencel nonwoven ...the Alfa fibers have a smaller fineness than that of fi- bers of ...
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A large, multicentre, observational, post-marketing surveillance study of the 2:1 formulation of follitropin alfa and lutropin alfa in routine clinical practice for assisted reproductive technology
... Approximately 70% of the current study population was aged ≥35 years. This might be expected as there is a general trend for delayed childbearing in Western soci- eties [19], with many couples seeking ART for this rea- ...
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The safety profile of drotrecogin alfa (activated)
... Drotrecogin alfa (activated; DrotAA) is the first and thus far only compound proven to improve survival in patients with severe sepsis. The mechanisms that underlie the improved survival are not entirely clear. A ...
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