ER stress response
Protein kinase CK2 in the ER stress response
... irradiation stress, heat shock stress has been shown to result in relocalization of CK2 sub- units to specific nuclear regions ...[12]. Stress activating agents like arsenite lead to an activation of ...
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4-Phenylbutyrate Attenuates the ER Stress Response and Cyclic AMP Accumulation in DYT1 Dystonia Cell Models
... the ER stress-signaling pathway, but how the mutation in torsinA causes disease remains ...induces ER stress, and inhibits the cyclic adenosine-39, 59-monophosphate (cAMP) response to ...
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The E3 ligase Hrd1 stabilizes Tregs by antagonizing inflammatory cytokine–induced ER stress response
... suppressing ER stress–induced Treg depolarization under inflammation ...trigger ER stress response in Tregs, which is further enhanced by genetic Hrd1 deletion; (b) pharmacological ...
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AMPK-independent inhibition of human macrophage ER stress response by AICAR.
... of ER stress marker mRNAs and pro-inflammatory ...macrophage ER stress responses triggered by ER-stressors thapsigargin or ...the ER stress response, but inhibited ...
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Transmission of ER stress response by ATF6 promotes endochondral bone growth
... It is reported that ER stress signal molecules were associated with chondrogenesis [19–21]. In this study, we sought to determine whether ATF6, an important transcription factor in ER stress, ...
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Japanese encephalitis virus co opts the ER stress response protein GRP78 for viral infectivity
... the ER becomes located toward the periphery of the cell relative to the assembly ...condensed ER structures is involved in the formation of the viral particle assembly compart- ment, especially in some ...
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Characterization of the nicotine-induced endoplasmic reticulum stress response in the rat placenta in vivo and in vitro
... augment ER stress in the rat placenta in vivo, however, it had yet to be discriminated the degree to which the direct and/or indirect cellular effects of nicotine were ...augment ER stress and ...
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Lutz, Anne Kathrin (2012): Der Einfluss Parkinson-assoziierter Gene auf mitochondriale Morphologie, Dynamik und Funktion. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... Mitochondrial stress induced by CCCP activates the UPR and leads to an upregulation of ...in response to mitochondrial membrane dissipation, induced by ...causes ER stress. (d) The ER ...
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Evaluation of the endoplasmic reticulum-stress response in eIF2B-mutated lymphocytes and lymphoblasts from CACH/VWM patients
... heightened stress response was demonstrated in several eIF2B-mutated models ...in stress regulation [10,11]. Later on, heightened ER-stress response mediated by hyper-induc- tion ...
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The cytotoxic effects of dimethyl sulfoxide in mouse preimplantation embryos: a mechanistic study
... adaptive response commonly induced to combat ER stress is ...either ER function or ER calcium homeostasis triggers autophagy and apoptotic cell ...against ER stress is not ...
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The role of death receptors in ER stress and Inflamation
... Production, ER Stress and DR5 Upregulation Taxanes, paclitaxel and docetaxel, have previously been shown to induce cytokines in sporadic studies and have classically been associated with secondary ...
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Stress Signaling Pathways for the Pathogenicity of Cryptococcus
... upon ER stress ...in ER stress response, the UPR pathway not only is involved in other environmental stress responses, including ther- motolerance and maintenance of cell wall ...
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Propranolol Improves Impaired Hepatic Phosphatidylinositol 3-Kinase/Akt Signaling after Burn Injury
... We have shown that propranolol ad- ministration after burn injury signifi- cantly attenuates all branches of the un- folded protein response. These results suggest that catecholamines play a role in potentiating ...
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Taurine reduces ER stress in C. elegans
... of ER stress by an increase in the level of skn-1, an anti-oxidative stress ...existing ER stress response accelerates the expression of skn-1 by factors from the stress ...
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Dengue 2 infection of HepG2 liver cells results in endoplasmic reticulum stress and induction of multiple pathways of cell death
... normal ER function [21]. The central mediator of the ER stress response is GRP78 (Glucose regulated protein 78 or BiP, Immuno- globulin heavy chain binding protein) and under normal conditions ...
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Coronavirus Infection Modulates the Unfolded Protein Response and Mediates Sustained Translational Repression
... determine if this attenuation of host cell mRNA translation is true of all coronaviruses, including the SARS coronavirus. However, the results of recent studies indicate that atypical innate and adaptive immune responses ...
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Hepatic steatosis in n-3 fatty acid depleted mice: focus on metabolic alterations related to tissue fatty acid composition
... Results: n-3 PUFA depletion leads to a significant decrease in body weight despite a similar caloric intake or adipose tissue weight. n-3 PUFA depleted mice exhibit hypercholesterolemia (total, HDL, and LDL cholesterol) ...
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Involvement of ER Stress in Human Primary Pterygium
... of ER is protein synthesis and folding ...the ER, which is also referred to as ‘ER stress’ [5], the unfolded or misfolded proteins accumulate in the ER, leading to the activation of ...
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Autophagy manipulation as a strategy for efficient anticancer therapies: possible consequences
... Moreover, ER stress in can- cer cells promotes the release of factors such as ROS that may transfer ER stress from tumor cells to the immune cells, such as DCs, in the tumor ...that ER ...
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The endoplasmic reticulum in plant immunity and cell death
... the ER in both MTI and ETI, and designates it as a potential effector ...targeting ER stress sensors to enhance folding of viral proteins or to modulate immune responses in mammals (Ke and Chen, ...
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