Erythrocyte Membrane Protein
Thrombin Cleavage of Plasmodium falciparum Erythrocyte Membrane Protein 1 Inhibits Cytoadherence
... falciparum erythrocyte membrane protein 1 (PfEMP1), a large family of variant surface antigens, each with up to seven extracellular domains that can bind to multiple host ...
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Abnormal erythrocyte membrane protein pattern in severe megaloblastic anemia
... the erythrocyte membrane protein pattern returned to ...the erythrocyte membrane protein pattern was ...normal. Erythrocyte membrane protein pattern of ...
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Erythrocyte Membrane Protein Band 3 Predicts Interferon Ribavirin Induced Anemia
... in erythrocyte membrane protein contents—especially band 4—take a role in the serious anemia related to interferon plus ribavirin ...the erythrocyte membrane protein contents ...
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Optimized expression of Plasmodium falciparum erythrocyte membrane protein 1 domains in Escherichia coli
... proteins to express with in vitro methods because of their extreme genetic codon usage. Different organisms have been applied for the production of malaria proteins, including Escherichia coli [1,2], baculovirus [3,4], ...
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Expression of Plasmodium falciparum erythrocyte membrane protein 1 in experimentally infected humans
... sites causing uncomplicated malaria [6-8]. It thus appears that expression of VSA SM confers a selective advantage in non-immune individuals, perhaps by allowing particu- larly efficacious endothelial sequestration and ...
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CD4+ T Cell Responses to the Plasmodium falciparum Erythrocyte Membrane Protein 1 in Children with Mild Malaria
... The immune response against the variant surface Ag Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) is a key component of clinical immunity against malaria. We have investigated the ...
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Prediction of solubility on recombinant expression of Plasmodium falciparum erythrocyte membrane protein 1 domains in Escherichia coli
... a protein by mutational replacement of non-polar amino acid residues with charged ones such as lysine has been shown to enhance intrinsic solubility of recombinant pro- teins ...
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Investigating the function of Fc -specific binding of IgM to Plasmodium falciparum erythrocyte membrane protein 1 mediating erythrocyte rosetting.
... Most Plasmodium falciparum infections in areas of stable parasite transmission produce only relatively mild symp- toms or are asymptomatic. Nevertheless, about 600 000 people, mainly children, die from severe malaria ...
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Antigenic cartography of immune responses to Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1)
... greater protein abundance on the red cell surface, stronger antigenic conservation, wider cross-reactivity or better ability to grow inside the host and thus become ...
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Paroxysmal nocturnal hemoglobinuria type III Lack of an erythrocyte membrane protein restricting the lysis by C5b 9
... integral membrane protein, designated C8- binding protein ...A protein with C8-binding capacity could not be ...the membrane of huE, inhibited the lysis of PNH-E by C5b-9 as well as the ...
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Acquisition of naturally occurring antibody responses to recombinant protein domains of Plasmodium falciparum erythrocyte membrane protein 1
... For protein expression BL21-CodonPlus-Ril competent cells (Stratagene) were ...MBP-fusion protein was puri- fied by chromatography on amylose resin as recom- mended by the manufacturer (New England ...
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Catecholamine regulation of human erythrocyte membrane protein kinase
... membranes from intact erythrocytes incubated with and without catecholamines. Activation of the enzyme is expressed as the ratio of the extent of phosphorylation of exogenous protein substrate in the absence to ...
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Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria
... falciparum erythrocyte membrane protein 1 (PfEMP1) is considered a key virulence factor in malaria, as it binds to various host receptors on the endothelium or UEs (rosetting) to sequester infected ...
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Enzymatic methyl esterification of erythrocyte membrane proteins is impaired in chronic renal failure Evidence for high levels of the natural inhibitor S adenosylhomocysteine
... enzyme protein carboxyl methyltransferase type II has been recently shown to play a crucial role in the repair of damaged ...examined erythrocyte membrane protein methyl esterification in ...
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The M18 aspartyl aminopeptidase of Plasmodium falciparum binds to human erythrocyte spectrin in vitro
... typical erythrocyte shape, alterations in the mechanical properties of the cell, and modifications of the phosphorylation state of erythrocyte membrane skel- eton ...falciparum erythrocyte ...
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A spiral scaffold underlies cytoadherent knobs in Plasmodium falciparum infected erythrocytes
... by membrane protrusions known as knobs, whose formation depends on the parasite-derived, knob-associated histidine-rich protein ...parasite-derived erythrocyte membrane protein ...of ...
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A Bacterial Phosphatase-Like Enzyme of the Malaria Parasite Plasmodium falciparum Possesses Tyrosine Phosphatase Activity and Is Implicated in the Regulation of Band 3 Dynamics during Parasite Invasion
... in erythrocyte membrane protein dynamics during the invasion ...fusion protein is detectable in vesicular structures in late-stage parasites and at the apical end of the invasive mero- zoite ...
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Association between erythrocyte Na+K+-ATPase activity and some blood lipids in type 1 diabetic patients from Lagos, Nigeria
... for erythrocyte ghost membrane ...haemoglobin-free membrane suspension was finally stored at -20°C in the 10 mM washing Tris-HCl buffer (pH ...and membrane protein ...
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STUDIES ON HUMAN ERYTHROCYTE MEMBRANE SURFACE CARBOHYDRATES.
... 3 protein suggesting remnants of photo ...typical protein profiles of reagent- derivatized membranes which have^undergone photocrosslinking with ...
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A Novel Erythrocyte Binding Protein of Plasmodium vivax Suggests an Alternate Invasion Pathway into Duffy Positive Reticulocytes
... Conclusions. Erythrocyte or reticulocyte invasion by malaria merozoites is central to blood-stage development of all malaria parasites. Plasmodium vivax has the distinctive characteristic of invading ...
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