Escherichia coli hemolysin A
Escherichia coli hemolysin is a potent inductor of phosphoinositide hydrolysis and related metabolic responses in human neutrophils
... Escherichia coli hemolysin (Hly) is a proteinaceous pore-forming exotoxin that probably represents a significant virulence factor in E. coli infections. We investigated its influence on human ...
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The lytic mechanism of Escherichia coli α hemolysin associated to outer membrane vesicles
... including Escherichia coli, Neisseria meningitidis, Pseudomonas aeruginosa, Hel- icobacter pylori, Shigella flexneri and Actinobacillus actinomycetemcomitans produce outer membrane vesi- cles and their ...
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Thromboxane mediated hypertension and vascular leakage evoked by low doses of Escherichia coli hemolysin in rabbit lungs
... E. coli hemolysin elicited a protracted, dose-dependent increase in the lung capillary filtration coefficient, which was independent of the prostanoid-mediated pressor response and resulted in severe ...
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Shiga Toxin, Cytolethal Distending Toxin, and Hemolysin Repertoires in Clinical Escherichia coli O91 Isolates
... Shiga toxin (Stx)-producing Escherichia coli (STEC) strains cause diarrhea and a life-threatening hemolytic-uremic syn- drome (HUS) worldwide (23, 44). STEC strains isolated from patients usually possess, ...
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Complex Multilevel Control of Hemolysin Production by Uropathogenic Escherichia coli
... (A) Hemolysin activity of S65EC, S65hlyA, and defined LPS inner core mutants and their complemented strains on sheep blood ...abolished hemolysin activity, while complementation restored this ...
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DETECTION OF VIRULENCE GENES(HLY,FIMH,KAPSMII) IN ESCHERICHIA COLI ISOLATES FROM BETA THALASSEMIC AND NON THALASSEMIC PATIENTS BY USING PCR TECHINQUE
... Background: Thalassemia is a hereditary anemia resulting from defects in hemoglobin production. Beta Thalassemia, caused by a decrease in the production of β-globin chains, affects multiple organs and associated with ...
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Treatment of enterohemorrhagic Escherichia coli (EHEC) infection and hemolytic uremic syndrome (HUS)
... E. coli, specifically STEC and E. coli- expressing intimin and HEC-hemolysin were treated by administration of pooled bovine colostrum, rich in anti- bodies to Shiga toxin and enterohemorrhagic ...E. ...
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High frequency of hybrid Escherichia coli strains with combined Intestinal Pathogenic Escherichia coli (IPEC) and Extraintestinal Pathogenic Escherichia coli (ExPEC) virulence factors isolated from human faecal samples
... E. coli human UTI strain UMEA- 3585-1 (PRJNA186355), a putative autotransporter gene encoding an uncharacterized protein identical to protein ...(HlyII) hemolysin protein and the leukotoxin genes ...
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Serotypes, hemolysin production and drug resistance among uropathogenic Escherichia coli isolated at a tertiary care hospital in Mumbai
... (UPEC) harbors virulence properties The study was undertaken to characterize the serotypes and multi drug resistance (MDR) in routinely Laboratory confirmed 105UPEC isolates, obtained by semi quantitative culture method ...
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The Extracellular Domain of the β2 Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity
... E. coli to express a hemolytic factor, now known as hemolysin (HlyA) ...E. coli strains recovered from uncomplicated UTIs, but in pyelonephritis or urosepsis isolates, 50 to 78% of strains contain ...
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Phenotypic and Genotypic Characterization of EnteropathogenicEscherichia coli (EPEC) strains in Tehran, Iran
... The presence of the stx gene was ascertained in all E. coli isolates by PCR using primers designed by Toma et al. (23) (Table 1). Shigatoxin producing E. coli (STEC) O157 was used as reference strain. A ...
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EspZ of Enteropathogenic and Enterohemorrhagic Escherichia coli Regulates Type III Secretion System Protein Translocation
... Enteropathogenic Escherichia coli (EPEC) and enterohemorrhagic E. coli (EHEC) are important diarrheal patho- gens responsible for significant morbidity and mortality in developing countries and the ...
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Fur Is the Master Regulator of the Extraintestinal Pathogenic Escherichia coli Response to Serum
... sion data were color coded by using a divergent color gradient (from blue for downregulated to red for upregulated). The Voronoi tree maps of the transcriptome induced by inactive se- rum and the pathways derived from it ...
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Bacterial Secretions of Nonpathogenic Escherichia coli Elicit Inflammatory Pathways: a Closer Investigation of Interkingdom Signaling
... nonpathogenic Escherichia coli strains on the human colonic cell line HCT-8 using next-generation transcriptome sequencing ...E. coli BL21 and W3110, while genetically very similar ...
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Screening and purification of nanobodies from E. coli culture supernatants using the hemolysin secretion system
... Purification of Nb‑HlyA fusions from culture supernatants To test the purification of secreted Nb-HlyA fusions, we chose the clones IB10, EC7 and TD4, which showed the higher binding signals against each antigen in ...
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... Background: Urinary tract infections are found to be commonest bacterial infections across the globe. Various studies have demonstrated high prevalence rate of UTIs in Pakistan. Multiple broad spectrum antibiotics are ...
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Metabolic Requirements of Escherichia coli in Intracellular Bacterial Communities during Urinary Tract Infection Pathogenesis
... ABSTRACT Uropathogenic Escherichia coli (UPEC) is the primary etiological agent of over 85% of community-acquired urinary tract infections (UTIs). Mouse models of infection have shown that UPEC can invade ...
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An Unexpected Route to an Essential Cofactor: Escherichia coli Relies on Threonine for Thiamine Biosynthesis
... PRA synthesis in a purF gnd mutant was inhibited by trypto- phan, another similarity with the pathway that functions in a purF gnd ridA mutant of S. enterica (Table 2) (15). In the presence of tryptophan, TrpR represses ...
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Molecular and Structural Characterization of a Novel Escherichia coli Interleukin Receptor Mimic Protein
... The agn43-yeeR-irmA genes are transcribed as a single tran- scriptional unit. To examine the transcriptional organization of the agn43-yeeR-irmA genes, we utilized a series of primers specific for each individual gene in ...
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Production, Purification and Characterization of Chicken Egg Yolk Monoclonal Antibody Against Colonization factor antigen -1 of Enterotoxigenic Escherichia coli Causing Diarrhea
... Enterotoxigenic Escherichia coli (ETEC) causes diarrhea in both humans and ...into Escherichia coli DH5α ...E. coli that may be useful for diagnosis of widely occurring ...
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