esophageal sphincter
The Genesis of Lower Esophageal Sphincter Pressure: Its Identification through the Use of Gastrin Antiserum
... The purpose of this study was to evaluate the role of gastrin in the genesis of lower esophageal sphincter (LES) pressure by the use of a high titer gastrin antiserum. Intravenous infusions of increasing ...
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Effect of continuous infusion of pentagastrin on lower esophageal sphincter pressure and gastric acid secretion in normal subjects
... lower esophageal sphincter pressure (LESP), and it has been suggested that serum gastrin concentration is the main physiological and pathophysiological regulator of ...
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Manometry of the Normal Upper Esophageal Sphincter and its Alterations in Laryngectomy
... upper esophageal sphincter (UES) were simultaneously studied with a conventional three-orifice Honeywell solid-state probe, an eight lumen radially perfused (RP) probe, and a circumferentially sensitive ...
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Neural Control of the Lower Esophageal Sphincter INFLUENCE OF THE VAGUS NERVES
... We performed studies in the opossum to define the influence of the vagi in the control of lower esophageal sphincter (LES) function. Bilateral vagotomy caused transient sphincter hypertension which ...
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Experimental induction of isolated lower esophageal sphincter relaxation in anesthetized opossums
... lower esophageal sphincter (LES) relaxation, defined as a transient sphincteric relaxation unaccompanied by esophageal peristalsis, has been shown to precede most episodes of gastroesophageal reflux ...
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Pressure tension, and force of closure of the human lower esophageal sphincter and esophagus
... The mechanical characteristics of the circular muscle of the human lower esophageal sphincter and esophagus were studied in subjects with competent and incompetent sphincters. Pressure-diameter curves were ...
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Mechanism of the Lower Esophageal Sphincter Relaxation ACTION OF PROSTAGLANDIN E1 AND THEOPHYLLINE
... The intravenous injection of prostaglandin E 1 (PGE 1 ) causes a dose-dependent relaxation of the lower esophageal sphincter (LES) in the intact, lightly anesthetized opossum. The action of PGE 1 is not ...
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The Adrenergic Control of Lower Esophageal Sphincter Function: AN EXPERIMENTAL MODEL OF DENERVATION SUPERSENSITIVITY
... lower esophageal sphincter (LES) function, LES pressure, LES relaxation during swallowing, and blood pressure were measured in the anesthetized opossum, Didelphis virginiana, during intravenous ...
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Interactions of bombesin and substance P at the feline lower esophageal sphincter
... The purpose of this study was to determine the interactions between bombesin and substance P at the feline lower esophageal sphincter (LES). Intraluminal pressures were recorded using a fixed, perfused ...
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Hormonal regulation of human lower esophageal sphincter competence: interaction of gastrin and secretin
... the sphincter to gastrin ...maximal sphincter response to gastrin I still attainable at higher ...A sphincter, endogenously stimulated by gastrin, showed a dose-related reduction in pressure with ...
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Generation of Nitric Oxide in the Opossum Lower Esophageal Sphincter during Physiological Experimentation
... endotoxins induce the inducible nitric oxide synthase (iNOS), which produces large amounts of nitric oxide (NO) and in turn, alters esopha- geal motor function. 1,2 Lipopolysaccharide (LPS) treatment results in an ...
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Is gastrin a major determinant of basal lower esophageal sphincter pressure? A double blind controlled study using high titer gastrin antiserum
... pressure. Gastrin antiserum or control antiserum was administered intravenously in successive doses of 0.02, 0.1, and 0.5 ml/kg on separate days. The lower esophageal sphincter pressures were measured for 1 ...
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Manometric Diagnosis of Lower Esophageal Sphincter Incompetence in Infants: Use of a Small, Single-Lumen Perfused Catheter
... Pressure tracing obtained from 3-month-old infant with chronic vomiting secondary to lower esophageal sphincter incompetence as catheter is withdrawn from stomach, through lower esophage[r] ...
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Effects of 5 hydroxytryptamine on the lower esophageal sphincter in vivo: evidence for multiple sites of action
... lower esophageal sphincter in the ...the sphincter was 0.5 mug/kg, and a maximal sphincter contraction was produced by a dose of 40 ...the sphincter pressure; maximal inhibition of ...
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Vasoactive intestinal polypeptide A neurotransmitter for lower esophageal sphincter relaxation
... lower esophageal sphincter region was incubated in solution that contained 12-25 parts of VIP antiserum per 1,000 to Tyrode's solution, while a second strip was incubated in a solution of normal rabbit ...
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Role of gastrin supersensitivity in the pathogenesis of lower esophageal sphincter hypertension in achalasia
... Intraluminal manometric studies were carried out in 19 patients with untreated achalasia and in 20 normals. Lower esophageal sphincter (LES) pressure was 50.5 ±4.6 mm Hg in patients with achalasia as ...
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Nature of the vagal inhibitory innervation to the lower esophageal sphincter
... the sphincter relaxation in response to a ganglionic stimulant, 1,1-dimethyl-4-phenylpiperazinium iodide (DMPP), did not block the sphincter relaxation in response to vagal stimulation at 10 pulses per ...
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The lower esophageal sphincter (LES)
... For a long time, hiatus hernia has been thought of as a major factor in the production of reflux. This assumption was based on the high incidence of sliding hiatal hernia in patients with gastroesophageal reflux 43,44 ...
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Mechanics of Sphincter Action STUDIES ON THE LOWER ESOPHAGEAL SPHINCTER
... lower esophageal sphincter ...lower esophageal sphincter as a function of the inside ...lower esophageal sphincter in ...lower esophageal sphincter around each ...
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Mechanism of action of pentagastrin on the lower esophageal sphincter
... The effects of pentagastrin on lower esophageal sphincter (LES) pressure has been studied in trained, unanesthetized dogs. LES pressure was monitored by an infusion manometric technique. Increasing doses of ...
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