eukaryotic elongation factor 1A
Cutaneous Human Papillomavirus Type 38 E7 Regulates Actin Cytoskeleton Structure for Increasing Cell Proliferation through CK2 and the Eukaryotic Elongation Factor 1A
... Human eukaryotic elongation factor 1A (eEF1A) was identified as one of the cellular pro- teins that associated with HPV38 E7 ...the elongation factor 1 complex, is responsible ...
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Eukaryotic Elongation Factor 1A Interacts with the Upstream Pseudoknot Domain in the 3′ Untranslated Region of Tobacco Mosaic Virus RNA
... and elongation factors EFTu and EFTs—involved in recogni- tion and initiation of RNA replication of Q RNA (5, ...of eukaryotic RNA viruses have been ...
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The eukaryotic translation elongation factor 1A regulation of actin stress fibers is important for infectious RSV production
... We previously demonstrated that eEF1A knock-down reduces RSV replication and subsequent shed virus [8]. Considering the role of actin in RSV trafficking and as- sembly [20] and the association between actin and eEF1A ...
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Elongation factor 1A-1 and hepatocyte response to fatty acid excess
... stress sensors. Following the release of GRP78 from PERK, PERK phosphorylates eukaryotic translation initiation factor 2 α (eIF2α). Phosphorylation of eIF2α blocks global protein synthesis while selectively ...
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Unique Classes of Mutations in the Saccharomyces cerevisiae G-Protein Translation Elongation Factor 1A Suppress the Requirement for Guanine Nucleotide Exchange
... G-proteins play critical roles in many cellular processes and are regulated by accessory proteins that modulate the nucleotide-bound state. Such proteins, including eukaryotic translation elongation ...
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MicroRNA-33a-5p Modulates Japanese Encephalitis Virus Replication by Targeting Eukaryotic Translation Elongation Factor 1A1
... JEV infection downregulates miR-33a-5p expression. To inves- tigate differentially expressed miRNAs during JEV infection, miRNA sequencing was performed and a large variety of up- or downregulated miRNAs was identified ...
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Conserved Protein Kinases Encoded by Herpesviruses and Cellular Protein Kinase cdc2 Target the Same Phosphorylation Site in Eukaryotic Elongation Factor 1δ
... (Fig. 1A) and tested whether the transiently ex- pressed recombinant EF-1␦ (EF-1␦[F]) behaves like endoge- nous EF-1␦ in COS-7 cells mock infected or infected with ...
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Overexpression of Translation Elongation Factor 1A Affects the Organization and Function of the Actin Cytoskeleton in Yeast
... HE eukaryotic translation elongation factor 1 efficiency and accuracy of translation in vivo and in (eEF1A, formerly EF-1␣) is a highly abundant pro- vitro (Sandbaken and Culbertson 1988; Dinman and ...
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Identification of a crenarchaeal orthologue of Elf1: implications for chromatin and transcription in Archaea
... the eukaryotic RNAP subunit RPB8 ...the eukaryotic transcription elongation factor ...In eukaryotic chromatin, nucleosomes consist of the highly conserved histone proteins H2A, H2B, H3 ...
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Overexpression of human virus surface glycoprotein precursors induces cytosolic unfolded protein response in Saccharomyces cerevisiae
... The eukaryotic translation elongation factor 1A (eEF1A, encoded by two identical yeast genes TEF1 and TEF2, also known as Tef2p) is localized in cell cytoplasm and has several important ...
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Eukaryotic Elongation Factor 1δ Is Hyperphosphorylated by the Protein Kinase Encoded by the UL13 Gene of Herpes Simplex Virus 1
... EF-1d plays an important role in regulation of protein syn- thesis. EF-1d is a subunit of EF-1, a complex of proteins which mediate the elongation of polypeptide chains during transla- tion of mRNA (18, 20, 32, ...
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Binding of the eukaryotic translation elongation factor 1A with the 5’UTR of HIV 1 genomic RNA is important for reverse transcription
... protein eukaryotic translation elongation factor 1A (eEF1A) binds to aminoacylated transfer RNAs and delivers them to the ribosome during ...
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Cyclic Rhamnosylated Elongation Factor P Establishes Antibiotic Resistance in Pseudomonas aeruginosa
... of elongation factor Tu (EF-Tu) in Mycobacterium tuberculosis (11) and Bacillus subtilis (12) and of glutamyl-tRNA synthetase in ...as eukaryotic initiation factor 5A (eIF5A), that also ...
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Maintenance of Transcription Translation Coupling by Elongation Factor P
... coli elongation factor P (EF-P), an elongation factor required for efficient translation of mRNAs containing consecutive proline codons, in maintaining coupled translation and ...
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Ribosomal Elongation Factor 4 Promotes Cell Death Associated with Lethal Stress
... A lepA deficiency diminishes effects of lethal agents. To better understand the role of EF4 when bacteria are faced with harsh stress, we examined the effects of three lethal antimicrobials on relevant bacterial mutants ...
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PKR and PP1C Polymorphisms in Alzheimer’s Disease Risk
... A bi-allelic polymorphism (rs2254958) located in a highly conserved SRp55 binding enhancer element of the EIF2AK2 gene (which encodes PKR protein) has been previously associated with age of AD onset and suscepti- bility ...
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Purification and characterization of elongation factor 2 (EF2) and cyclic AMP-independent protein kinases from soybean (Glycine max, L) cotyledons.
... 60,000 - 112,000 (Merrick et al., 1975; Galasinski and Moldave, 1969; Collins et al., 1971; Twardowski and Legocki, 1973; Mizumoto et al., 1974; Comstock and Van, 1977). EF2 contains twenty two cysteine groups and the ...
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Jarasch, Alexander (2011): 3D modeling of ribosomal RNA using cryo-electron microscopy density maps. Dissertation, LMU München: Fakultät für Chemie und Pharmazie
... In this dissertation we present a new approach for modeling and tting large structured RNAs into cryo-EM density maps. Our homology modeling approach lead to highly accurate models of the common ribosomal core structure. ...
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Everolimus enhances cellular cytotoxicity of lapatinib via the eukaryotic elongation factor-2 kinase pathway in nasopharyngeal carcinoma cells
... Methods: The Cell Counting Kit 8 and colony formation assay were used to detect the effect of lapatinib alone or lapatinib combined with everolimus on the growth and proliferation of cells. Apoptosis was tested by flow ...
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Structural Basis for EarP Mediated Arginine Glycosylation of Translation Elongation Factor EF P
... ranslation elongation is a nonuniform process and directly depends on the amino acids (aa) to be incorporated into the growing polypeptide chain ...the eukaryotic and archaeal elongation ...
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