Ex-Vivo
DESIGN AND COMPARATIVE EVALUATION OF CLARITHROMYCIN GASTRIC BIOADHESIVE TABLETS BY EX VIVO AND IN VIVO METHODS
... for ex vivo and in vivo studies and compared with hydroxypropyl methylcellulose K100 polymer by evaluating gastric retention period by X-ray imaging technique, and drug bioavailability by a ...
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Flavivirus Infection of Ixodes scapularis (Black Legged Tick) Ex Vivo Organotypic Cultures and Applications for Disease Control
... Transfection of the LGTV 3= UTR dsRNA in LGTV- and POWV-infected tick organs led to a decrease in not only infectious LGTV replication but also infectious POWV repli- cation by at least 10-fold in both a midgut (Fig. S4A ...
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Introduction of an ex vivo pig model for teaching percutaneous nephrolithotomy access techniques
... This study compares trainees’ assessment of two low-cost models for percutaneous access, a silicone model and an ex-vivo pig organ model. The ex vivo pig organ model is attractive because its ...
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A Porcine Ex Vivo Lung Perfusion Model To Investigate Bacterial Pathogenesis
... the ex vivo lung perfusion (EVLP) model of infection using porcine lungs to investigate Klebsiella pneumoniae-triggered pneumonia as a model of respiratory ...
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Ex vivo lung perfusion review of a revolutionary technology
... transplant. Ex vivo lung perfusion (EVLP) is widely expanding technology to assess and prepare the lungs who are considered marginal for ...of ex vivo, and the logics and rationales for ...
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Phosphorylation of TOPK at Y74, Y272 by Src increases the stability of TOPK and promotes tumorigenesis of colon cancer
... activity of TOPK, and the phosphorylation TOPK at T9 can not promote tumorigenesis (Supplementary Figure S1). There must exist other activation mechanisms of TOPK related to tumorigenesis. So far it is only reported that ...
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PIOGLITAZONE MICROCAPSULES: FORMULATION AND IN VITRO EX VIVO CHARACTERIZATION
... From the research work findings, it could be concluded that the microcapsules formulation F6 containing 2 % hydroxyl propyl cellulose, is the best optimized formulation as it possess maximum encapsulation efficiency, ...
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EXPERIMENTAL MODELS TO STUDY TUMOUR ANGIOGENESIS – IN VITRO, EX VIVO AND IN VIVO APPROACH
... The impact of different culture conditions can be assessed by spotting the change in the size of the wound area. Cellular behavior is measured for further detailed examination. Spontaneous cell tracking in phase contrast ...
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Abnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupus
... mice ex vivo We also found that CD40 expression was highly significantly upregulated in DCs from spleens of diseased NZM2410 mice in comparison with age-matched non-autoimmune mice (Fig- ure ...
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Experimental manipulation of radiographic density in mouse mammary gland
... and matrigel created a region of density (arrowheads) dis- tinguishable from the surrounding normal gland (Fig. 3c,3f). Such regions were not present in any of the untreated con- tralateral glands, which served as ...
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FORMULATION AND EVALUATION OF ATENOLOL BUCCAL PATCHES BY USING, CAESALPINIA POLYMER AND TAMARIND POLYMER FOR THE TREATMENT OF HYPERTENSION
... uniformity, Ex vivo Mucoadhesive strength, % swelling index, folding endurance and in vitro drug release, Determination of Residence Time, Ex Vivo Permeation Study which produced satisfactory ...
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Functional role of thromboxane production by acutely rejecting renal allografts in rats
... by ex vivo perfused renal allografts increased progressively from 2 to 6 d after ...in vivo clearance of inulin and the log of ex vivo TXB2 ...
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New Avenues for Nanoparticle Related Therapies
... settings, ex vivo organ perfusion provides a new route to repair injury of isolated organs in the absence of ...in vivo lung perfusion techniques and other isolated organ perfusion provides ...
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Ex vivo rheology of spider silk
... In this work, we have used two new micro-rheometric devices that utilize less than 5· l of fluid for a test and enable the measurement of the steady and transient rheological properties of ex vivo samples ...
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Oxidized LDL reduces monocyte CCR2 expression through pathways involving peroxisome proliferator–activated receptor γ
... The CCR2-mediated recruitment of monocytes into the vessel wall plays an important role in all stages of atherosclerosis. In recent studies, we have shown that lipoproteins can modulate CCR2 expression and have ...
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Comparative Analysis of Biotissue Laser Resection Using Strongly Absorbing Optical Fiber Tips
... We used the laser scalpel LCP-0,97/10 (Azor LLC, Russia) operating in the mode of cw generation at the wave- length of 0.97 µm. The radiation was delivered to tissue by replaceable silica fibers 550 µm in diameter. Pre- ...
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INTRANASAL DRUG DELIVERY – NEW CONCEPT OF THERAPEUTIC IMPLICATIONS FOR EFFECTIVE TREATMENT OF CNS DISORDERS
... in vivo data, but it can often provide insight into questions regarding the human metabolism of a drug prior to the initiation of clinical studies and finally, leading to less number of animals required to confirm ...
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ORAL DELIVERY OF ROSUVASTATIN LIPID NANOCARRIERS: INVESTIGATION OF IN VITRO ANDIN VIVO PROFILE
... release. Ex vivo intestinal permeability through chick ileum revealed improvement in apparent permeability coefficient due to lipid coated nano- sized ...In vivo absorption of ROS from lipid ...
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High potency ligands for DREADD imaging and activation in rodents and monkeys
... in vivo DREADD agonist, we performed in vivo electrophysiology experiments in which hM4Di was co-expressed with a new light-drivable channelrho- dopsin, ChrimsonR (Supplementary ...
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Long term administration of traditional kampo medicine shimotsuto, juzentaihoto and unseiin inhibits experimental thrombosis in mice
... the ex-vivo technique of shear-induced platelet reactivity measurement (haemostatometry) and the in vivo test of endothelial function (flowmediated vaso- dilation) were also used to assess the mecha- ...
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