excretory secretory
Parasite excretory-secretory products and their effects on metabolic syndrome
... . Further promoting this TH1-TH2 switch, products from the parasite can also significantly enhance IL-4 production in the draining LN 59 . In addition, there is growing evidence to suggest that other intracellular ...
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Suppression of ovine lymphocyte activation by Teladorsagia circumcincta larval excretory-secretory products
... Parasitic nematodes regulate host immune responses through a number of mechanisms including interference with antigen processing, modulation of macrophage and antigen-presenting cell function, interference with cyto- ...
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Characterisation of a niche specific excretory–secretory peroxiredoxin from the parasitic nematode Teladorsagia circumcincta
... ES: excretory–secretory; Prx: peroxiredoxin; 2DE: 2D electrophoresis; PDB: Protein Data Bank; CAP: cysteine‑rich secretory proteins, antigen 5, and pathogenesis‑ related 1 proteins; ShK: ...
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Analysis of Diagnostic Efficiency of Excretory Secretory Antigens for Trichinella spiralis and Trichinella nativa in ELISA
... The analysis was performed by using indirect variant with polystyrene 96-pits strip microplates from Gosniipo- limer, Moscow. For solid phase sensitization excretory-secretory antigens with molecular mass ...
8
Definitive host influences the proteomic profile of excretory/secretory products of the trematode Echinostoma caproni
... Although comparative immunological and pathophysio- logical studies regarding how hosts enable chronic infec- tions or rapidly promote parasite rejection are extensive in the E. caproni-rodent model, there is limited ...
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Characterisation of proteins in excretory/secretory products collected from salmon lice, Lepeophtheirus salmonis
... Proteases are also secreted by L. salmonis [12–14] as well as other parasitic copepod species [15] and are thought to be important for feeding and immune eva- sion. Serine proteases such as trypsins, thought to be of L. ...
9
Extracellular vesicles from parasitic helminths contain specific excretory/secretory proteins and are internalized in intestinal host cells
... The study of host-parasite interactions has increased considerably in the last decades, with many studies focusing on the identification of parasite molecules (i.e. surface or excretory/secretory proteins ...
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Definitive host influences the proteomic profile of excretory/secretory products of the trematode Echinostoma caproni
... Although comparative immunological and pathophysio- logical studies regarding how hosts enable chronic infec- tions or rapidly promote parasite rejection are extensive in the E. caproni-rodent model, there is limited ...
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Development of a Highly Specific RecombinantToxocara canis Second Stage Larva Excretory Secretory Antigen for Immunodiagnosis of Human Toxocariasis
... The specificity of the recombinant Toxocara canis antigen developed for the immunodiagnosis of human toxocariasis was compared with that of the excretory-secretory antigen from T. canis second-stage larvae ...
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Leishmanial Excretory-Secretory proteins: A potent vaccine candidate
... their excretory-secretory proteins/factors which may act as antigens are easily purified form culture supernatant of cultured Leishmania ...leishmanial excretory-secretory antigens serve as a ...
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Comparative study of excretory–secretory proteins released by Schistosoma mansoni resistant, susceptible and naïve Biomphalaria glabrata
... glabrata SCW excretory–secretory proteins ESPs were fractionated using SDS-PAGE, identified with LC-MS/MS and compared to naïve snail ESPs.. Protein-protein interaction PPI analyses base[r] ...
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DNA methylation and hydroxymethylation profiles reveal possible role of highly methylated TLR signaling on Fasciola gigantica excretory/secretory products (FgESPs) modulation of buffalo dendritic cells
... Fasciola gigantica is considered the main liver fluke spe- cies responsible for fascioliasis in domestic animals and humans across vast land areas in tropical and subtropi- cal regions. It causes great livestock economic ...
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Purified protein derivative of Mycobacterium tuberculosis and excretory secretory antigen(s) of Toxocara canis expand in vitro human T cells with stable and opposite (type 1 T helper or type 2 T helper) profile of cytokine production
... Abstract A large series of T cell clones TCC specific for purified protein derivative PPD of Mycobacterium tuberculosis total 60 or Toxocara canis excretory/secretory TES antigen total 6[r] ...
6
Isolation and identification of excretory-secretory and somatic antigens from the Oestrus ovis larvae by SDS-PAGE and immunoblotting
... of larvae was checked under a stereomicroscope. The somatic crude extracts (S) were prepared as follows: A total number of 10 second (L2) and one third (L3) stage larvae were separately sonicated with a Bandelin ...
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Early serodiagnosis of trichinellosis by ELISA using excretory–secretory antigens of Trichinella spiralis adult worms
... their excretory–secretory (ES) antigens can be prepared by the in vitro cultivation of isolated muscle larvae, resulting in a preparation with high specificity ...
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Immunoprotection in sheep against Haemonchus contortus using its thiol-purified excretory/secretory proteins
... Excretory/Secretory antigen was prepared by culturing live adult worms of Haemonchus contortus in RPMI 1640 medium at a concentration of 50 worms per mL in a culture-flask at 37 ˚C for 24 hr and the culture ...
6
Analysis of Entamoeba histolytica Excretory-Secretory Antigen and Identification of a New Potential Diagnostic Marker
... Serodiagnosis of amoebiasis remains the preferred method for diagnosis of amoebic liver abscess (ALA). However, the commercially available kits are problematic in areas of endemicity due to the persistently high ...
5
Use of cloned excretory/secretory low molecular weight proteins of Cooperia oncophora in a serological assay
... The potential of Cooperia oncophora excretory/secretory (ES) proteins as antigens in a serological assay which aims to establish exposure levels in cattle was assessed. ES proteins were analyzed by one- and ...
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Identification of early diagnostic antigens from major excretory secretory proteins of Trichinella spiralis muscle larvae using immunoproteomics
... larval excretory-secretory (ES) antigen or the synthetic antigen 3,6-dideoxy-D-arabi- nohexose (tyvelose)] for detecting the specific anti-Trichi- nella antibody IgG are not positive in pigs and mice ...
8
Immunoproteomic analysis of the excretory secretory products of Trichinella pseudospiralis adult worms and newborn larvae
... (PCHTP) were also identified in several spots. The PCHTP as a metalloprotein is a new nematode ES-specific protein family of PCHTP-Poly-cysteine proteins, which are unique to order Trichocephalida [45, 46]. In previous ...
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