exosomal RNA
Exosomal transfer of proteins and RNAs at synapses in the nervous system
... mouse exosomal RNA to human mast cells, new mouse proteins were found in the recipient cells, indicating that transferred exosomal mRNA can be translated after entering another ...intercellular ...
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<p>Serum Exosomal Long Noncoding RNA pcsk2-2:1 As A Potential Novel Diagnostic Biomarker For Gastric Cancer</p>
... non-coding RNA of more than 200 bp in length, is aberrancy abundant in many exosomes and related to the development and progress of various tumors including bladder cancer, 5 cervical cancer, 6 lung cancer, 7 col- ...
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Serum exosomal miR-4772-3p is a predictor of tumor recurrence in stage II and III colon cancer
... Exosomal RNA was extracted using the SeraMir exosome RNA kit (SBI, Mountain View, CA, USA) according to the manufacturer’s ...the RNA was determined using the Small RNA Chip and Agilent ...
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PubMedCentral-PMC4880137.pdf
... circulating exosomal albumin mRNA were observed at subtoxic APAP ...in exosomal albumin mRNA were also observed in primary rat hepatocytes at subtoxic APAP ...both exosomal albumin mRNA and ...
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Exosomal miRNAs as potential biomarkers of cardiovascular risk in children
... Exosome-mediated RNA transfer is believed to be an effect- ive method for cell signaling and the exosomal RNA will certainly impact biological processes in the recipient cells ...[32,60,109]. ...
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<p>Plasma Exosomal Long Noncoding RNA lnc-SLC2A12-10:1 as a Novel Diagnostic Biomarker for Gastric Cancer</p>
... c exosomal lncRNA and investigate the potential diagnostic value of plasma exosomal lncRNA in ...isolated. Exosomal RNA was extracted, and lncRNA microarray assay was performed to identify ...
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<p>Exosomal Long Non-Coding RNA CEBPA-AS1 Inhibits Tumor Apoptosis and Functions as a Non-Invasive Biomarker for Diagnosis of Gastric Cancer</p>
... against RNA degradation, and enhance the stability of RNA in circulating ...and exosomal RNA can accurately re fl ect the changes occurring in cancer cells during tumor ...derived ...
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Role of exosomal small RNA in prostate cancer metastasis
... With the accumulating evidence from preclinical studies, clinical trials have recently been launched. The Medical College of Wisconsin (Milwaukee, Wisconsin) sponsored a study in June 2017 that is recruiting PCa patients ...
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Original Article Circulating exosomes and exosomal lncRNA HIF1A-AS1 in atherosclerosis
... and exosomal lncRNA HIF in ...the exosomal RNA was isolated and exosomal lncRNA HIF1A-AS1 was quantified using real-time polymerase chain reaction ...of exosomal lncRNA HIF1A-AS1 were ...
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Placenta derived exosomes continuously increase in maternal circulation over the first trimester of pregnancy
... extract exosomal total RNA from fresh and frozen plasma by following the manufacturer’s ...stabilize RNA and inactivate ...semi-pure RNA samples, removing most of the other cellular ...the ...
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Immune-related MicroRNAs are Abundant in Breast Milk Exosomes
... of exosomal RNA in breast milk Raw milk ...Total RNA from exosomes was extracted using TRIzol-LS (Invitrogen, CA, USA) following the man- ufacturer’s ...the RNA 6000 Nano LabChip Kit (Agilent, ...
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Exosomal miRNA: an alternative mediator of cell-to-cell communication
... MicroRNAs (miRNAs) are a class of small, non-coding RNAs with a length of approximately 22 nucleotides [1]. MicroRNAs play a role in vast range of physiological and pathological processes by post-transcriptionally ...
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<p>Advances in the diagnosis of exosomal miRNAs in ischemic stroke</p>
... and exosomal miRNAs are new potential serum markers for ...contain exosomal miRNAs, the two may not necessarily be ...in exosomal miR-126 levels, which may be more sensitive to cerebral ischemia, ...
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The role of exosomal transport of viral agents in persistent HIV pathogenesis
... genomic RNA in order to facil- itate virion assembly [73], this may be a mechanism by which those elements are sorted into exosomes as well, though this hypothesis has yet to be ...
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<p>Circulating serum exosomal aHIF is a novel prognostic predictor for epithelial ovarian cancer</p>
... serum exosomal aHIF and the fl ux photons from the tumors were analyzed by Spearman ’ s correlation coef fi - ...serum exosomal aHIF levels and clinicopathological variables were analyzed by the Chi square ...
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Exosomal miRNAs in hepatocellular carcinoma development and clinical responses
... using exosomal miRNAs in clinical diagnostics and therapeutics, because they have improved stability in exosomes than as free miRNAs ...themselves. Exosomal miRNAs act through novel mechanisms for inducing ...
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Exosomal cell-to-cell transmission of alpha synuclein oligomers
... Results: Using a novel protein fragment complementation assay where α syn is fused to non-bioluminescent amino-or carboxy-terminus fragments of humanized Gaussia Luciferase we demonstrate here that α syn oligomers can be ...
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The crosstalk between autophagic and endo-/exosomal pathways in antigen processing for MHC presentation in anticancer T cell immune responses
... T cells recognize antigen fragments from proteolytic products that are presented to them in the form of peptides on major histocompatibility complex (MHC) molecules, which is crucial for the T cell to identify infected ...
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Commercial and Emerging Technologies for Cancer Diagnosis and Prognosis Based on Exosomal Biomarkers
... Immunologic separation techniques target exosomal surface proteins with antibodies for selective isolation. Popular commercially available kits based on this technique are the enzyme-linked immunosorbent assay ...
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Tetraspanin CD63 Bridges Autophagic and Endosomal Processes To Regulate Exosomal Secretion and Intracellular Signaling of Epstein-Barr Virus LMP1
... DNA constructs. GFP and GFP-LMP1 constructs were generated as described previously (19). Mutants were subcloned into the pQCXP vector (number 17386; Addgene) from pBabe-expressing plasmids previously constructed (77) ...
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