experimental allergic encephalomyelitis
Immune response after experimental allergic encephalomyelitis in rats subjected to calorie restriction
... Male Lewis rats (6 weeks-old) were submitted to a calorie restriction equivalent to 33% or 66% of food restriction. Fifteen days later, groups of 7 animals were injected with complete Freund's adjuvant plus spinal cord ...
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Cytokine and chemokine alterations in tissue, CSF, and plasma in early presymptomatic phase of experimental allergic encephalomyelitis (EAE), in a rat model of multiple sclerosis
... Background: Experimental allergic encephalomyelitis (EAE) is the most commonly used experimental animal model for human multiple sclerosis (MS) that has been used so far to study the acute and ...
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eae36, a Locus on Mouse Chromosome 4, Controls Susceptibility to Experimental Allergic Encephalomyelitis in Older Mice and Mice Immunized in the Winter
... to experimental allergic encephalomyelitis (EAE), the principal animal model of MS, is also influenced by nongenetic factors, including age and season at ...
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Experimental allergic encephalomyelitis in pituitary-grafted Lewis rats
... Treatment of susceptible rats with dopaminergic agonists that reduce prolactin release decreases both severity and duration of clinical signs of experimental allergic encephalomyelitis (EAE). To ...
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Neural Stem Cells Transplantation Promotes Brain Repair after Chronic Experimental Allergic Encephalomyelitis in Rat
... The recent studies have showed neural stem cells (NSCs) transplantation promoted repair and functional recovery of chronic experimental allergic encephalomyelitis (EAE) animal model for MS based on ...
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Experimental allergic encephalomyelitis in cynomolgus monkeys Quantitation of T cell responses in peripheral blood
... relapsing-remitting experimental allergic encephalomyelitis (EAE) was induced in cynomolgus monkeys by a single immunization with a homogenate of human brain white matter (BH) in ...
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Modulation of cell-mediated hypersensitivity in experimental allergic encephalomyelitis
... ABBREVIATIONS BSA Bovine serum albumin CFA Complete Freunds Adjuvant CNS Central Nervous System Con A Concanavalin A CSF Cerebrospinal fluid DFO Desferrioxamine DMEM Dulbeccos modified E[r] ...
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Homologies between T cell receptor junctional sequences unique to multiple sclerosis and T cells mediating experimental allergic encephalomyelitis
... Abstract The selection of T cell clones with mutations in the hypoxanthine guanine phosphoribosyltransferase hprt gene has been used to isolate T cells reactive to myelin basic protein M[r] ...
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Use of vitamins for correction of the functional state of cytochrome P450 systems at experimental allergic encephalomyelitis
... Застосування разом із вітаміном D 3 вітамінів-антиоксидантів Е та С позначилося деяким впливом на цитохром P450-залежну систему мікросом мозку, в той час як доповнення раціону твари[r] ...
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Distinct roles for B7 1 (CD 80) and B7 2 (CD 86) in the initiation of experimental allergic encephalomyelitis
... encephalomyelitis (EAE). In adoptively transferred EAE, in vitro activation of myelin basic protein (MBP)-specific lymph node cells was inhibited by the combination of anti-CD80 plus anti-CD86, but not ...
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Regulation of susceptibility and resistance to experimental allergic encephalomyelitis by neuroendocrine and immune factors
... demonstrated. T cell reactivity to MBP, proteolipid protein (PLP) and other myelin proteins such as myelin associated glycoprotein (MAG) and myelin oligodendrocyte glycoprotein (MOG) can be demonstrated from peripheral ...
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Strategies for the identification of loci responsible for the pathogenesis of multiple sclerosis
... (Experimental Allergic Encephalomyelitis) and of previously identified QTL that have been shown to be linked to the ...good experimental organism for a first application of this ...
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Lymphotoxin α revisited: general features and implications in rheumatoid arthritis
... Abbreviations CIA, collagen-induced arthritis; EAE, experimental allergic encephalomyelitis; ELISA, enzyme-linked immunosorbent assay; FLS, fibroblast-like synoviocyte; GVHD, graft-versu[r] ...
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Antibody facilitation of multiple sclerosis like lesions in a nonhuman primate
... Abbreviations used in this paper: CNS, central nervous system; CSF, cerebrospinal fluid; EAE, experimental allergic encephalomyelitis; GFAP, glial fibrillary acidic protein; MBP, myelin [r] ...
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Angiogenesis in multiple sclerosis and experimental autoimmune encephalomyelitis
... an experimental model of MS, experimental allergic encephalomyelitis (EAE), where blood – brain barrier disruption and vascular remodelling appeared in a pre-symptomatic disease ...
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In healthy primates, circulating autoreactive T cells mediate autoimmune disease
... Abbreviations used in this paper: APC, antigen-presenting cells; CNS, central nervous system; CSF, cerebrospinal fluid; EAE, experimental allergic encephalomyelitis; MBP, myelin basic pr[r] ...
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Long term inhibition of murine experimental autoimmune encephalomyelitis using CTLA 4 Fc supports a key role for CD28 costimulation
... Adoptive transfer of experimental allergic encephalomyelitis in SJL/J mice after in vitro activation of lymph node cells by myelin basic protein: requirement for Lytl +2+ T lymphocytes..[r] ...
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<p>Protective Effects of Leukadherin1 in a Rat Model of Targeted Experimental Autoimmune Encephalomyelitis (EAE): Possible Role of P47phox and MDA Downregulation</p>
... Experimental autoimmune encephalomyelitis (EAE) is a common animal model used to study MS. In regular EAE induction, myelin oligodendrocyte peptide (MOG) is emulsified with adjuvant and then injected ...
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T cells in multiple sclerosis and experimental autoimmune encephalomyelitis
... Cutting edge: CD4+CD25+ regulatory T cells suppress antigen-specific autoreactive immune responses and central nervous system inflammation during active experimental autoimmune encephalo[r] ...
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Schubart, Anna (2002): Aspects of the Immunobiology of Myelin Oligodendrocyte Glycoprotein (MOG)-induced Experimental Autoimmune Encephalomyelitis (EAE). Dissertation, LMU München: Fakultät für Biologie
... Type I and II lesions show a striking resemblance to the lesions seen in certain models of experimental autoimmune encephalomyelitis (EAE), an animal model of MS initiated by an autoimmune response to CNS ...
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