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Experimental animal

Considering aspects of the 3Rs principles within experimental animal biology

Considering aspects of the 3Rs principles within experimental animal biology

... Refinements to reduce the invasiveness of a procedure can be as simple as improving the manner in which animals are handled. Hurst and West (2010) showed that handling mice by allowing them to voluntarily sit in a cupped ...

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EVALUATION OF ANTIPYRETIC AND ANALGESIC ACTIVITY OF  ARTOCARPUS HETROPHYLLUS IN EXPERIMENTAL ANIMAL MODELS

EVALUATION OF ANTIPYRETIC AND ANALGESIC ACTIVITY OF ARTOCARPUS HETROPHYLLUS IN EXPERIMENTAL ANIMAL MODELS

... The jackfruit (Artocarpus heterophyllus) is a species of tree in the mulberry family (Moraceae), which is native to parts of South and Southeast Asia. It is called Katahal in Hindi, medium-size evergreen tree typically ...

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Evaluation of Anti-inflammatory and Analgesic Activities of Tithonia diversifolia in Experimental Animal Models

Evaluation of Anti-inflammatory and Analgesic Activities of Tithonia diversifolia in Experimental Animal Models

... of experimental animal when exposed to heat and mechanical stimuli and carrageenan administration as a measure of anti-nociceptive and anti-inflammatory effects of the ...

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MAKING AN EXPERIMENTAL ANIMAL MODEL FOR MULTIPLE SCLEROSIS

MAKING AN EXPERIMENTAL ANIMAL MODEL FOR MULTIPLE SCLEROSIS

... To understand the mechanism of Multiple Sclerosis (MS), an autoimmune demyelinating disease, the researchers developed an experimental animal model for MS, which is called EAE (Experimental Allergic ...

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Evaluation of anti inflammatory activity on the leaves of Filicium decipiens in experimental animal models

Evaluation of anti inflammatory activity on the leaves of Filicium decipiens in experimental animal models

... suitable experimental animal model for evaluating the anti-edematous effect of natural products [8], and this is believed to be triphasic, the first phase (1hr after carrageenan challenge) involves the ...

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Enhancement in Cortical Arousal by Caffeine Salicylate in Experimental Animal Models

Enhancement in Cortical Arousal by Caffeine Salicylate in Experimental Animal Models

... In the present communication CNS stimulant, analge- sic and antinflammatory property of caffeine salicylate and vis a vis contribution of two molecules caffeine and salicylic acid in these activities in a combinatorial ...

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VARIED ANTI  INFLAMMATORY ACTIVITY OF INDOMETHACIN IN DIFFERENT EXPERIMENTAL ANIMAL MODELS

VARIED ANTI INFLAMMATORY ACTIVITY OF INDOMETHACIN IN DIFFERENT EXPERIMENTAL ANIMAL MODELS

... CONCLUSION: In the light of the above mentioned observations even an established anti-inflammatory agent (Indomethacin) has not shown considerably equal anti-inflammatory activity against all conventional models of ...

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Investigations into the pathogenesis of diabetic erectile dysfunction: An experimental animal model

Investigations into the pathogenesis of diabetic erectile dysfunction: An experimental animal model

... In rats, intracavernous injection of different drugs known to act at different levels of the adenosine 3’5’ cyclic monophosphate (cAMP) and cGMP pathways revealed that neither cAMP nor drugs that stimulate adenylate ...

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 ANTIDEPRESSANT ACTIVITY OF A POLYHERBAL FORMULATION R013, IN EXPERIMENTAL ANIMAL MODEL

 ANTIDEPRESSANT ACTIVITY OF A POLYHERBAL FORMULATION R013, IN EXPERIMENTAL ANIMAL MODEL

... For FST Porsolt et al., (1977) method was used. Each animal was positioned individually in a 5 litre glass beakers, filled with water up to a height of 15 cm and were observed for duration of 6 minutes. The ...

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Pharmacological Evaluation of Indian Medicinal Plant Clitoria Ternatea (L) in Experimental Animal

Pharmacological Evaluation of Indian Medicinal Plant Clitoria Ternatea (L) in Experimental Animal

... The animal were returned to the observation chamber for 4 hr then the animals were sacrificied by decapitation method, the abdomen of each was opened and the stomach was isolated after suturing the lower ...

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Pharmacological Evaluation of Canthium Coromandelicum (Burm.F) Alston in Experimental Animal Models

Pharmacological Evaluation of Canthium Coromandelicum (Burm.F) Alston in Experimental Animal Models

... Traditional healers and pharmacists in developing countries are in important source of information about plant sources of new drugs. Only a fraction of the earth's natural pharmacopoeia has been analyzed with modern ...

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EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF LILIUM CANDIDUM L IN EXPERIMENTAL ANIMAL MODELS

EVALUATION OF HEPATOPROTECTIVE ACTIVITY OF LILIUM CANDIDUM L IN EXPERIMENTAL ANIMAL MODELS

... Wistar albino rats of both sexes (180-220 g) were used for the study. All the rats were kept in standard plastic rat cages with stainless steel coverlids and wheat straw was used as bedding material. The animals were ...

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Evaluation of Pharmacological Potential of Ruzu Herbal Bitter in Experimental Animal Model

Evaluation of Pharmacological Potential of Ruzu Herbal Bitter in Experimental Animal Model

... Eighteen Wistar albino rats of both male and female sex were used for this study. The animals were obtained from the Animal Breeding Unit of the College of Veterinary medicine, University of Nigeria, Nsukka. They ...

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ANTIULCER ACTIVITY OF CINNAMOMUM TAMALA LINN. LEAVES EXTRACT IN EXPERIMENTAL ANIMAL

ANTIULCER ACTIVITY OF CINNAMOMUM TAMALA LINN. LEAVES EXTRACT IN EXPERIMENTAL ANIMAL

... The present investigation is an attempt to utilize the herbal flora for gastrointestinal disorder like ulcer and their respective therapeutic effect on human sufferings. Herbal medicines are easily acceptable by the ...

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Effects of Cytokine Therapy for Treatment and Prophylaxis of Hydatidosis in Experimental Animal Model (Mice)

Effects of Cytokine Therapy for Treatment and Prophylaxis of Hydatidosis in Experimental Animal Model (Mice)

... of experimental model of alveolar echinococcosis with IFN- γ (1-5 μg twice in week for three weeks) reduced parasite burden in liver and it was suggested that administration of IFN- γ with appropriated drug is ...

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Intestinal Lesions Associated with Disseminated Candidiasis in an Experimental Animal Model

Intestinal Lesions Associated with Disseminated Candidiasis in an Experimental Animal Model

... 1⫻ phosphate-buffered saline (PBS). The concentration of the inoculum was determined by hemocytometer counts and confirmed by dilution plating on YPD. Experimental animals. The derivation and maintenance of GB ...

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A Comprehensive Review On Experimental Animal Models To Induce Schizophrenia

A Comprehensive Review On Experimental Animal Models To Induce Schizophrenia

... various animal models for Schizophrenia. Numerous animal models are available in order to induce Schizophrenia but the question remains unclear that which animal model would be the most appropriate ...

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Evaluation of the Analgesic and Antipyretic Actions of the Saraca Asoca Leaves in Experimental Animal Models

Evaluation of the Analgesic and Antipyretic Actions of the Saraca Asoca Leaves in Experimental Animal Models

... Animals Used: Male Albino rats weighing 150-200 gm were obtained from School of Pharmaceutical Sciences, Jaipur National University. All the animals were housed in clean metabolic cages placed in well ventilated house ...

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Evaluation of Comparative Immunomodulatory Potential of Solanum xanthocarpum Root and Fruits on Experimental Animal

Evaluation of Comparative Immunomodulatory Potential of Solanum xanthocarpum Root and Fruits on Experimental Animal

... Wistar albino rats (150-200 gm) of either sex obtained from Institutional Animal House of B.R. Nahata College of Pharmacy, Mandsaur for the study. Animals were maintained under normal environmental condition: ...

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Clinical, microbiological, and experimental animal studies of Candida lipolytica

Clinical, microbiological, and experimental animal studies of Candida lipolytica

... The index isolate caused persistent fungemia with catheter-associated Candida thrombophlebitis, the second isolate was from a polymicrobial sinusitis, and the remaining four isolates wer[r] ...

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