extracellular pH
Extracellular pH changes activate the p38 MAPK signalling pathway in the amphibian heart
... Our results indicate that p38-MAPK activation in the amphibian heart follows a different pattern according to the type of extracellular pH change. Acidosis at pH·6.5 caused a moderate but prolonged ...
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The Fungal Pathogen Candida albicans Autoinduces Hyphal Morphogenesis by Raising Extracellular pH
... Role of Ato proteins in environmental alkalinization by C. albicans. Four of the genes highly induced during alkalinization relative to the levels for both control conditions encode homologs of a family of ...
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Effects of temperature and extracellular pH on metabolites: kinetics of anaerobic metabolism in resting muscle by 31P and 1H NMR spectroscopy
... gradient and (2) is intracellularly produced by metabolism. In all tissues, the maintenance of ion gradients across cell membranes constitutes an important fraction of the cellular energy consumption. Energy supply, ...
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Reduced extracellular pH increases endothelin 1 secretion by human renal microvascular endothelial cells
... ET-1 secretion is regulated predominantly by transcription and is modulated by various hormones and physical forces (11, 13). Only small amounts of ET-1 are stored in vascular endo- thelial cells and most are released ...
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Osteoclast function: Role of extracellular pH and ATP
... of extracellular pH on mammalian osteoclastic resorption seem clear ...low pH on resorption by rat osteoclasts diminished over several days in culture; although these experiments studied the effects ...
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In Vivo Indicators of Cytoplasmic, Vacuolar, and Extracellular pH Using pHluorin2 in Candida albicans
... intracellular pH. As such, the capacity to detect pH changes in real time and within live cells is of fundamental importance to essentially all as- pects of ...a pH-sensitive variant of green ...
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Robust Extracellular pH Modulation by Candida albicans during Growth in Carboxylic Acids
... the extracellular pH, both in vitro and in the macrophage phago- some (14); this pH manipulation induces the hyphal morphogen- esis that characterizes the ...the pH phenotype has not been ...
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Dynamic Nucleolar Targeting of Dengue Virus Polymerase NS5 in Response to Extracellular pH
... contrast, analysis of NS5 using FRAP determined NS5 nucleolar trafficking to be highly dynamic (Fig. 4). After bleaching of a re- gion of the nucleolus containing GFP-tagged NS5 (red box), NS5 levels rapidly increased in ...
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THE EFFECT IN HUMANS OF EXTRACELLULAR pH CHANGE ON THE RELATIONSHIP BETWEEN SERUM POTASSIUM CONCENTRATION AND INTRACELLULAR POTASSIUM
... In order to control the effect of changes in total body potassium on the serum potassium concentration experimental periods were short and an attempt was made to change potassium balance[r] ...
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Acidic extracellular pH promotes epithelial mesenchymal transition in Lewis lung carcinoma model
... In vitro invasive activity was determined using Matrigel®- coated filter mounted transwell chambers (Corning, Tewksbury, MA, USA) as described [43]. Briefly, cells were serum-starved overnight at pH 7.4 and then ...
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Acidic Extracellular pH Induces Vascular Endothelial Growth Factor (VEGF) in Human Glioblastoma Cells via ERK1/2 MAPK Signaling Pathway
... lular pH of ...acidic pH and VEGF up-regulation in U87 MG human glioma cells. Acidic pH has been shown to up-regulate VEGF and basic fibroblast growth factor expression in human endothelial cells ...
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The effects of extracellular pH and of the transcriptional regulator PACI on the transcriptome of Trichoderma reesei
... The pH-responsive genes were divided into different func- tional classes according to the Eukaryotic orthologous groups (KOG) classification (Figure ...the pH- responsive genes was classified as having a ...
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Switch from Metabolic to Ventilatory Compensation of Extracellular pH in Crayfish
... Third, during a decrease of water titration alkalinity which induces a hypercapnic acidosis, Dejours & Armand, 1980 associated with a decrease of water NaCl concentration [NaCl]w the reg[r] ...
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Lin28A induces energetic switching to glycolytic metabolism in human embryonic kidney cells
... controls. Extracellular pH flux analysis indicated that Lin28A over expression significantly increased the rate of glycolysis, whilst high resolution oxygen respirometry demonstrated a reduced oxygen ...
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Ion exchange mechanisms on the erythrocyte membrane of the aquatic salamander, Amphiuma tridactylum
... Effects of adrenaline, DIDS and amiloride on the water content, extracellular pH pHe, intracellular pH pH,, and on the pH gradient ApH of Amphiuma tridactylum erythrocytes equilibrated w[r] ...
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The renal response to acid loads in metabolic alkalosis; an assessment of the mechanisms regulating acid excretion
... extracellular pH towards normal cannot be invoked to account for the increased acid excretion; in dogs ingesting a diet deficient in sodium and potassium, there was no renal response to [r] ...
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Regulation of cell pH by ambient bicarbonate, carbon dioxide tension, and pH in the rabbit proximal convoluted tubule
... cell pH by ambient pH, carbon dioxide tension (PCO2), and bicarbonate (HCO3), cell pH was measured in the isolated, in vitro microperfused rabbit proximal convoluted tubule using the fluorescent dye ...
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Effects of acid base variables on in vitro hepatic metabolism in rainbow trout
... The effects of hypercapnia 1 % CO2, and the independent effects of changes in extracellular pH pHe, Pco2 ar| d [HCO3~] on intracellular pH measured by the DMO method and lactate metaboli[r] ...
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The role of pH, PCO2, and bicarbonate in regulating rat diaphragm citrate content
... physiologic extracellular pH value of approximately ...external pH values of 7.15, implying that at these two extracellular pH levels (HCO 3 - ) primarily determines citrate ...
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Water pH limits extracellular but not intracellular pH compensation in the CO2 tolerant freshwater fish Pangasianodon hypophthalmus
... intracellular pH protection during extracellular pH depression is associated with hypercarbia tolerance in white sturgeon, Acipenser ...intracellular pH measurements in fish exposed to ...
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