extracellular traps
Role of the lipoxin A4 receptor in the development of neutrophil extracellular traps in Leishmania infantum infection
... Neutrophils, as the largest group of immune cells, recruited by numerous parasite-, host- and sand fly- derived chemotactic factors in the process [4], are the first to reach the Leishmania infiltration site [5–8] and ...
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Experimental lupus is aggravated in mouse strains with impaired induction of neutrophil extracellular traps
... Many effector mechanisms of neutrophils have been implicated in the pathogenesis of systemic lupus erythematosus (SLE). Neutrophil extracellular traps (NETs) have been assigned a particularly detrimental ...
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Activation of conventional protein kinase C (PKC) is critical in the generation of human neutrophil extracellular traps
... PKC. Extracellular traps from both neutro- phils and mast cells have been demonstrated in psoriatic skin lesions and from purified neutrophils from psoriasis patients in association with IL-17 and MPO, ...
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Neutrophil extracellular traps and the dysfunctional innate immune response of cystic fibrosis lung disease: a review
... Presently around 11,000 people in the UK suffer from CF and the median age of death is only 28 [1], with one third of patients dying whilst waiting for a lung trans- plant as morbidity and mortality principally relate to ...
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Neisseria gonorrhoeae Elicits Extracellular Traps in Primary Neutrophil Culture While Suppressing the Oxidative Burst
... Neutrophil extracellular traps (NETs) were observed in gonococcus-infected PMNs, a process which requires an oxidative burst, yet gonococci induced NETs under suppressing ...
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Gastropod derived haemocyte extracellular traps entrap metastrongyloid larval stages of Angiostrongylus vasorum, Aelurostrongylus abstrusus and Troglostrongylus brevior
... Phagocyte-derived extracellular traps (ETs) were recently demonstrated mainly in vertebrate hosts as an important effector mechanism against invading ...invertebrate extracellular phagocyte trap ...
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Neutrophil extracellular traps in the host defense against sepsis induced by Burkholderia pseudomallei (melioidosis)
... Neutrophil extracellular traps (NETs; another effector mechanism of neutrophils) consist of extracellular DNA and histone-based structures decorated by antimicrobials such as neutrophil elastase and ...
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Degradation of neutrophil extracellular traps co varies with disease activity in patients with systemic lupus erythematosus
... degradation of dying cells [1-4]. Numerous genes have been associated with the disease, spanning from immune modulatory genes to complement factors [5], all crucial to ensure a proper immune response and efficient ...
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Streptococcus agalactiae Induces Placental Macrophages To Release Extracellular Traps Loaded with Tissue Remodeling Enzymes via an Oxidative Burst Dependent Mechanism
... identified placental leukocytes as being able to secrete MMPs, including MMP-1, -7, and -9 (78). Several MMPs have been implicated in preterm birth and pathological preg- nancies. MMP-1 and MMP-9 were found to be elevated ...
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<p>Destruction of Neutrophil Extracellular Traps Promotes the Apoptosis and Inhibits the Invasion of Gastric Cancer Cells by Regulating the Expression of Bcl-2, Bax and NF-κB</p>
... Neutrophil extracellular traps (NETs) are a new neutrophil death mode found in recent ...of extracellular DNA which is surrounded by adhesion of neutrophil-associated ...
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Placental histology and neutrophil extracellular traps in lupus and preeclampsia pregnancies
... In SLE vasculopathy, the imbalance between vascular damage and repair is characterised in part by increased endothelial cell apoptosis and decreased number and function of endothelial progenitor cells. 35 A similar phe- ...
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Original Article Procoagulant role of neutrophil extracellular traps in patients with gastric cancer
... neutrophil extracellular traps (NETs) trigger coagulation through an intrinsic pathway and contribute to thrombus initiation and ...and extracellular DNA as well as a modified capture ELISA ...
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Platelets induce neutrophil extracellular traps in transfusion related acute lung injury
... neutrophil extracellular traps (NETs) as a potential explanation for the neutrophil- and platelet-dependent lung damage in ...killing extracellular pathogens in blood and tis- sues during infection ...
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Neutrophil extracellular traps sequester circulating tumor cells and promote metastasis
... Neutrophil extracellular traps (NETs) are extracellular neutrophil-derived DNA webs released in response to inflammatory cues that trap and kill invading patho- ...
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Primary tumors induce neutrophil extracellular traps with targetable metastasis-promoting effects
... Metastasis remains the leading cause of death among cancer patients. The role of the tumor immune microenvironment (TIME) in cancer initiation, progression, and treatment efficacy is well established (1) and has led to ...
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Neutrophil extracellular traps — the dark side of neutrophils
... Neutrophil extracellular traps (NETs) are extracellular strands of decondensed (unwound) DNA in complex with histones and neu- trophil granule ...
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Neutrophil extracellular traps (NETs) are increased in the alveolar spaces of patients with ventilator associated pneumonia
... Background: Neutrophils release neutrophil extracellular traps (NETs) in response to invading pathogens. Although NETs play an important role in host defense against microbial pathogens, they have also been ...
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Neutrophil extracellular traps in sheep mastitis
... of extracellular traps (ETs) [12,15,16]. Neutrophil extracellular traps (NETs) are rep- resented by a mesh of DNA, histones, antimicrobial pro- teins and proteinases, that entrap and ...
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High mobility group box 1 potentiates antineutrophil cytoplasmic antibody inducing neutrophil extracellular traps formation
... neutrophil extracellular traps (NETs), generated by ANCA-activated neutrophils, are in- creasingly recognized as another important aspect in the pathogenesis of AAV [7, ...
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Predictors of neutrophil extracellular traps markers in type 2 diabetes mellitus: associations with a prothrombotic state and hypofibrinolysis
... neutrophil extracellular traps; OR: odds ratio; PAD: peripheral artery disease; PAI-1: plasminogen activa- tor inhibitor-1; TAFI: thrombin activatable fibrinolysis inhibitor; TG: thrombin generation; T2DM: ...
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