Extracellular vesicle (EVs)
ISEV position paper: extracellular vesicle RNA analysis and bioinformatics
... Interestingly, EVs were found to be enriched in several types of such non-coding RNA species ...for extracellular vesicle RNA (evRNA) trafficking and release, in addition to the function of this RNA ...
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Extracellular vesicle-mediated delivery of miR-101 inhibits lung metastasis in osteosarcoma
... derived EVs; AD-MSC-NC-EVs: AD-MSC-NC- derived EVs; anti-DIG-HRP: anti-digoxigenin- horseradish peroxidase; BCL6: B cell lymphoma 6; EV: extracellular vesicle; EV-miRNAs: EV-packaged ...
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Extracellular vesicle cross-talk in the bone marrow microenvironment: implications in multiple myeloma
... serum EVs expressing the ectoenzyme CD38 [110], a marker of plasma cells and an often used MM-related antigen was found, implicating that these vesicles originate from MM cells ...serum EVs in MM patients ...
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Extracellular vesicle-based drug delivery systems for cancer treatment
... cell-derived EVs for therapeutic purposes is the presence of tumor-specific antigens that can prime immune cells to induce an immune ...Loading EVs with inhibitors of immunosuppressive cells or ...
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3D visualization of extracellular vesicle uptake by endothelial cells
... HUVEC. EVs were isolated from the cell culture medium via differential centrifugation and used for the uptake ...the EVs was measured using TRPS technology on a qNano ...of EVs was observed using a ...
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Myristoylated CIL-7 regulates ciliary extracellular vesicle biogenesis
... to extracellular vesicles (EVs). EVs may be used by cells as a form of intercellular communication and mediate a broad range of physio- logical and pathological ...urinary EVs released from ...
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Extracellular Vesicle-Mediated RNA Release in Histoplasma capsulatum
... capsulatum EVs from the G186AR strain and 38 from the G217B ...capsulatum EVs consisted of tRNAs (Table ...in EVs, we searched for the components of the RNA interference (RNAi) machinery in ...
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Extracellular vesicle cross-talk between pulmonary artery smooth muscle cells and endothelium during excessive TGF-β signalling: implications for PAH vascular remodelling
... these EVs in the spotlight as potential contributors for EndoMT, thus they might play an im- portant role in vascular remodelling occurring during ...in EVs, which im- plies enrichment in EVs at both ...
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Extracellular vesicle proteomes reflect developmental phases of Bacillus subtilis
... Results: Bacillus subtilis were observed to release EV to a similar extent during sporulation as during the vegetative growth phase. However, the two vesicular cargos show qualitatively and quantitatively different ...
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Extracellular vesicle isolation and characterization: toward clinical application
... As discussed above, two broad categories of EVs are released from the human colon cancer cell line LIM1863 (37), exosomes and sMVs. Over the past decade, our laboratory has accumulat- ed exhaustive proteomic ...
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Extracellular Vesicle Integrins Distinguish Unique Cancers
... of extracellular vesicles (EVs) has been of increasing interest, particularly in understanding cancer growth, drug resistance, and metastatic ...cancer-derived EVs carry an array of oncogenic cargo, ...
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Abstract: Extracellular vesicles (EVs) are membranous vesicles secreted by both prokaryotic and
... 1. Extracellular vesicle subpopulations and common isolation ...methods. EVs are categorized into three types depending on their site of origin or ...
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Mesenchymal Stromal/stem Cell-derived Extracellular Vesicles Promote Human Cartilage Regeneration In Vitro
... Bone marrow derived MSC, similar to other cell types in the body, secrete different subsets of extracellular vesicles. So far the immunomodulatory and/or tissue repair properties of BMMSC-EVs have been ...
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Circulating platelet-derived vesicle in atrial fibrillation
... The population of the platelet-derived vesicles is the largest in other types of EVs in the circulation. Indeed, the majority of the blood-borne EVs are thought to originate from the megakaryocytes, i.e. ...
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Quantitative proteomic analysis and functional characterization of Acanthamoeba castellanii exosome like vesicles
... 16]. Extracellular vesicles (EVs) that are secreted into the extracellular milieu have emerged as key players in intercellular communication without direct cellular ...contact. EVs can be ...
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Heterologous and cross-species tropism of cancer-derived extracellular vesicles
... loading EVs even with a large biopharmaceutical oncolytic viruses (OVs) did not significantly change their charge and dimension properties, while increasing their anti-neoplastic activity compared to the virus or ...
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Human immunodeficiency virus type 1 Vpu protein is an oligomeric type I integral membrane protein.
... CD4 is inserted into membranes with its extracellular hydrophilic portion facing into the lumen of the membrane vesicle and the cytoplasmic C-terminal domain facing the outside of the mi[r] ...
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Hookworm secreted extracellular vesicles interact with host cells and prevent inducible colitis in mice
... (Tm) extracellular vesicles (EVs) were analyzed in a separate independent experiment (see Figure S1 in Supplementary Material) and included only for ...
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Mesenchymal stromal cell-derived extracellular vesicles attenuate lung ischemia-reperfusion injury and enhance reconditioning of donor lungs after circulatory death
... on EVs-derived from MSCs, rather than using MSCs themselves, as a thera- peutic tool which can be administered safely via different routes thereby circumventing the issue of cell retention and ...viability. ...
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Protective effect of miRNA-containing extracellular vesicles derived from mesenchymal stromal cells of old rats on renal function in chronic kidney disease
... Unfortunately, the function of MSCs is known to decline with age, which may result in a reduction in the maintenance of tissue homeostasis leading to organ failure and diseases of ageing [6]. The prolifer- ative activity ...
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