Extrinsic apoptotic pathway
Chandipura Virus Induces Neuronal Death through Fas-Mediated Extrinsic Apoptotic Pathway
... Extrinsic Apoptotic Pathway Sourish Ghosh, Kallol Dutta,* Anirban Basu National Brain Research Center, Manesar, Haryana, India Chandipura virus (CHPV; genus Vesiculovirus, family Rhabdoviridae) is an ...
9
Castanea sativa Mill bark extract exhibits chemopreventive properties triggering extrinsic apoptotic pathway in Jurkat cells
... the extrinsic apoptotic pathway, while the intrinsic apoptotic pathway appeared not to be ...in apoptotic cells was evidenced in both activated caspase-8 assay ...
11
Study of Extrinsic Apoptotic Pathway in Oral Pemphigus Vulgaris Using TNFR 1 and FasL Immunohistochemical Markers and TUNEL Technique
... investigate extrinsic apoptotic pathway in oral pemphi- gus vulgaris using TUNEL and important immunohistochemical markers of extrinsic pathway, TNFR1 and ...
10
Activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway in human lung cancer cells by the new synthetic flavonoid, LZ-205
... These results indicated that LZ-205 induces a mitochondrial dependent apoptotic pathway. At the same time, we found the cleaved-caspase 8, Fas and FasL levels were also increased, while expression of ...
14
Wound fluids collected from patients after IORT treatment activates extrinsic apoptotic pathway in MCF7 breast cancer cell line
... two apoptotic pathways: extrinsic and intrinsic, on the transcript level upon incubation of breast cancer MCF7 cell line with wound fluids collected from patients after breast cancer conserving surgery or ...
7
<p>6,7-Dihydroxy-2-(4′-hydroxyphenyl)naphthalene induces HCT116 cell apoptosis through activation of endoplasmic reticulum stress and the extrinsic apoptotic pathway</p>
... totic pathway in H460 cells, which are known to harbor the wild-type p53 ...of extrinsic apoptosis and ER stress pathways in p53-wild-type HCT116 cells, but not in p53-mutant HT-29 cells, suggesting that ...
13
Protein S blocks the extrinsic apoptotic cascade in tissue plasminogen activator/N-methyl D-aspartate-treated neurons via Tyro3-Akt-FKHRL1 signaling pathway
... Therefore, we studied whether PS can activate TAM receptors during a tPA/NMDA insult. Results: We show that PS protects neurons from tPA/NMDA-induced apoptosis by suppressing Fas-ligand (FasL) production and ...
12
Cyathula prostrata ethanol extract activates the extrinsic pathway of apoptosis in HeLa and U937 cell lines
... Death-receptor extrinsic apoptotic pathway activation Cyathula prostrata is a medicinal plant that is used in tropical Africa, Asia and Australia to treat many ailments in- cluding rheumatic fever, ...
8
The effect of Astragalus polysaccharides on attenuation of diabetic cardiomyopathy through inhibiting the extrinsic and intrinsic apoptotic pathways in high glucose stimulated H9C2 cells
... the apoptotic process. Apoptosis is mediated mainly by the extrinsic apoptotic pathway and the intrinsic apoptotic pathway [13, ...35]. Extrinsic apoptosis is initiated ...
12
Myricetin inhibits proliferation of cisplatin-resistant cancer cells through a p53-dependent apoptotic pathway
... and extrinsic or receptor-mediated ...totic pathway is ...intrinsic apoptotic pathway through controlling the permeability of the mitochondrial membrane and the release of pro-apoptotic ...
11
Retama monosperma n hexane extract induces cell cycle arrest and extrinsic pathway dependent apoptosis in Jurkat cells
... and extrinsic apoptotic pathways in this process, we fur- ther investigated molecular events related to both apop- totic pathways in Rm-HE-treated Jurkat ...receptor-activated extrinsic ...
12
Antiproliferative and apoptotic effects of black turtle bean extracts on human breast cancer cell line through extrinsic and intrinsic pathway
... the apoptotic effects of BTB extracts on human breast cancer cell ...their apoptotic effects were characterized by DNA fragmentation, nuclear staining assay, mitochondrial membrane potential analysis, ...
10
The Major Apoptotic Pathway Activated and Suppressed by Poliovirus
... the pathway resulting in the apoptotic death of po- liovirus-infected cells and to map the step of this pathway that is suppressed by the viral antiapoptotic ...specific apoptotic pathways, we ...
12
Apoptotic cells trigger a membrane initiated pathway to increase ABCA1
... of apoptotic cells daily and, during this process, take up large quantities of ...the apoptotic cell clearance process is linked to macrophage ABCA1 expression is not ...signaling pathway that drives ...
12
BCDO2 acts as a carotenoid scavenger and gatekeeper for the mitochondrial apoptotic pathway
... SUMMARY Carotenoids and their metabolites are widespread and exert key biological functions in living organisms. In vertebrates, the carotenoid oxygenase BCMO1 converts carotenoids such as , -carotene to retinoids, ...
12
Staphylococcus aureus Exploits the Host Apoptotic Pathway To Persist during Infection
... IMPORTANCE Caspase-3 controls the apoptotic pathway, a form of programmed cell death designed to be immunologically silent. Polymorphisms leading to reduced caspase-3 activity are associated with variable ...
12
Antitumor effects of traditional Chinese medicine targeting the cellular apoptotic pathway
... on apoptotic pathways are summarized in Table ...the apoptotic pathway and inhibit the growth of pancreatic cancer cells both in vitro and in ...
10
Taxol-Induced Mitotic Block Triggers Rapid Onset of a p53-Independent Apoptotic Pathway
... However, multimininucleated cells only began to exhibit positive TUNEL staining from 3 days onwards after G1 arrest in a much more staggered fashion (Fig. 5 K and L; Hs578T cells are sho[r] ...
21
Both the apoptotic suicide pathway and phagocytosis are required for a programmed cell death in Caenorhabditis elegans
... sistent with that of an undead B.al/rapaav in late fourth larval stage animals and interpreted such a cell as one that had failed to undergo programmed cell death. In this way, we confirmed that B.al/rapaav cell death is ...
14
Evodiamine Induces Extrinsic Apoptosis Through P38 Mapk Pathway and Inhibits Autophagy in Gallbladder Cancer
... signaling pathway was significantly associated with evodiamine-treated apoptosis of gallbladder cancer cells, and the depletion of p53 was related with decreasing ...
7