F-box protein 32
F-box proteins: more than baits for the SCF?
... the F-box protein Pof14 and the Erg9 squalene synthase, a key enzyme in ergosterol metabolism, was also recovered in a two-hybrid screen (Table ...its F-box or other SCF components ...
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The F box protein ZEITLUPE controls stability and nucleocytoplasmic partitioning of GIGANTEA
... the F-box protein ...GI-GFP protein levels in ...and protein levels determined by ...GI protein were normalized to ADK and H3, respectively, and further normalized to empty ...
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The F-Box Protein Fbp1 Regulates Sexual Reproduction and Virulence in Cryptococcus neoformans
... Cryptococcus neoformans is a basidiomycetous yeast patho- gen that often infects the central nervous system (CNS) to cause meningitis, predominantly in immunocompromised in- dividuals (11). The pathogen has emerged as ...
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Cloning and Bioinformatics Analysis of Rosa rugose S Locus F Box Gene (RrSLF)
... Locus F-box Gene was cloned for the first time from the pollen of Rosa rugosa “Zilong wochi” with RT-PCR and RACE methods and named as RrSLF ...derived protein has a molecular weight of 43.7 kD, a ...
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F-Box Protein RcyA Controls Turnover of the Kinesin-7 Motor KipA in Aspergillus nidulans
... RcyA F-box protein in a yeast two-hybrid screening with KipA as ...motor protein of ...an F-box domain at the N ter- ...Sec10, F-box proteins at the N termi- nus, ...
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The F Box Protein Fbp1 Shapes the Immunogenic Potential of Cryptococcus neoformans
... Deletion of Fbp1 does not affect the expression of several major virulence factors in C. neoformans. In previous studies, we determined that deletion of Fbp1 from C. neoformans strain H99 resulted in hypovirulence in ...
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The F-box protein Cdc4/Fbxw7 is a novel regulator of neural crest development in Xenopus laevis
... (Ba) persists, while staining in the fin mesenchyme (Fin), another neural crest-derived tissue, becomes prominent (Figure 1I-K). Expression in anterior placodes also becomes pronounced at stage 32 (Figure 1K, ...
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Clink, a Nanovirus-Encoded Protein, Binds both pRB and SKP1
... instance, F-box proteins and the ubiquitin-proteasome pathway are involved in the control of the ploidy level ...of F-box proteins was recently described for yeast Cdc4p and Grr1p (52) and ...
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The F box protein family
... plant F-box proteins, UFO and FIM, are required for flower development in Arabidopsis thaliana and Antirrhinum majus, respectively ...these F-box proteins bind to Skp1 proteins, it is unclear ...
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F box protein FBXW7 inhibits cancer metastasis in a non cell autonomous manner
... The FBXW7 gene is a potent tumor suppressor, as evidenced by the many corresponding mutations associated with human can- cer (37) as well as by the tumor formation observed in conditional knockout mice (38, 39, 41). The ...
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Baculovirus F-Box Protein LEF-7 Modifies the Host DNA Damage Response To Enhance Virus Multiplication
... nuclear F-box protein that interacts with host S-phase kinase-associated protein 1 (SKP1), suggesting that LEF-7 acts as a substrate recognition component of SKP1/Cul- lin/F-box ...
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The Saccharomyces cerevisiae F-Box Protein Dia2 Is a Mediator of S-Phase Checkpoint Recovery from DNA Damage
... in protein turnover during cell-cycle progression (Ang and Harper ...an F-box protein, which provides specificity of the com- plex (Feldman et ...cerevisiae F-box protein ...
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Lessons from Fungal F-Box Proteins
... Most F-box proteins discussed in this review are from ...that F-box proteins perform in a eukaryotic ...other F-box proteins from fission yeast and filamentous fungi give an ...
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Regulation of SCF ubiquitin ligases by Jab1/Csn5 and the Cop9 signalosome
... several protein bands found in hCul1 IPs but not in controls (Figure ...several F-box proteins, eight proteins were identified that corresponded to the entire complex of the Cop9 Signalosome ...
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Purification and Chemistry of Bacteriophage ϰ
... weight, based on the assumption that the buoyant density for the phage protein is 1.3 [the value for an average protein 32] and the buoyant density for the phage DNA is 1.72 [the value f[r] ...
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Opposite Roles of the F-Box Protein Rcy1p and the GTPase-Activating Protein Gyp2p During Recycling of Internalized Proteins in Yeast
... (Ausubel et al. 1991). PCR reactions were performed with the a CAAX-box motif at its carboxyl terminus, which medi- Expand polymerase kit as recommended by the manufacturer ates its interaction with membranes ...
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Targeting proteins for ubiquitination and degradation in the treatment of human disease
... Another subclass of ubiquitin ligases is the plant homeodomain (PHD) or Leukemia associated-protein (LAP) domain containing E3s, which have eight con- served metal binding ligands (C4HC3) with similar spacing to ...
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Plasma from septic shock patients induces loss of muscle protein
... Results: Myosin content was approximately 25% lower in myotubes exposed to plasma from septic shock patients than in myotubes exposed to plasma from controls (P < 0.01). Furthermore, patient plasma increased ...
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Small Trypanosome RNA-Binding Proteins TbUBP1 and TbUBP2 Influence Expression of F-Box Protein mRNAs in Bloodstream Trypanosomes
... cyclin F-box. F-box proteins are components of SCF E3 ubiquitin ligase complex- es; they act as bridging factors between unstable proteins and the ubiquitination machinery and are important in ...
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New insights into posttranslational modifications of Hippo pathway in carcinogenesis and therapeutics
... regulatory protein SAV1, phosphorylates and activates the LATS kinases and ...like protein 4 (VGL4), repressing target gene expression involved in cell ...
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