F. nucleatum
A Novel Small Molecule, 1,3-di-m-tolyl-urea, Inhibits and Disrupts Multispecies Oral Biofilms
... Based on these results, we asked if DMTU inhibited multispecies biofilms by inhibiting inter- species communication (quorum sensing) mechanisms. Therefore, we investigated the effects of DMTU on the biofilm and virulence ...
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Citation: Shah C, Moolani Y, Campbell S (2015) Epidemiological Characteristics of Infections Associated with Culture Isolated Fusobacterium Nucleatum : A Retrospective Analysis. J Case Rep Stud 3(1): 103. doi: 10.15744/2348-9820.2.403
... We have reported a series of 40 cases of Fusobacterium nucleatum infections from a general county hospital population in an urban setting. In our study, skin and soft tissue infections were the most frequent sites ...
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Forward Genetic Dissection of Biofilm Development by Fusobacterium nucleatum: Novel Functions of Cell Division Proteins FtsX and EnvC
... the F. nucleatum FtsX protein sequence shared only ...S1D). F. nucleatum mutants devoid of FtsX and EnvC cell division homologs are ...for F. nucleatum led us first to develop an ...
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Application of rpoB and Zinc Protease Gene for Use in Molecular Discrimination of Fusobacterium nucleatum Subspecies
... Fusobacterium nucleatum is a Gram-negative spindle-shaped bacteria that may play an important role in periodontal disease ...(1). F. nucleatum has been reported to coaggregate with most oral ...
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Infected Iliac Artery Aneurysm Concomitant with Liver Abscess Caused by Fusobacterium nucleatum
... F. nucleatum is one of the most prevalent species in extra-oral sites under disease conditions ...sampled, F. nucleatum was probably the causative bacterium of the abscesses on the basis of ...
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Could gut microbiota serve as prognostic biomarker associated with colorectal cancer patients’ survival? A pilot study on relevant mechanism
... Nowadays, cancer stage is the most important indicator for the prognosis of CRC patients, and multiple strategies were well designed based on different TNM stage. However, new tool to indicate more accurate clinical ...
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Perturbed human sub-networks by Fusobacterium nucleatum candidate virulence proteins
... of F. nucleatum and human proteins, and ultimately provided a list of candidate virulence proteins and their human interactors that can be ex- perimentally exploited to test new hypotheses on the ...
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Fusobacterium nucleatum Promotes Metastasis in Colorectal Cancer by Activating Autophagy Signaling via the Upregulation of CARD3 Expression
... Figure 5. CARD3 is Involved in F. nucleatum-Mediated Autophagy. (A) Domain architecture of CARD3 and alignment of the LIR motifs (pink) between humans and rodents. (B) Western blot analysis was performed ...
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Is a fusobacterium nucleatum infection in the colon a risk factor for colorectal cancer?: a systematic review and meta-analysis protocol
... F. nucleatum is now considered to be a pathogenic bacterium of the gut that can invade the colorectal submucosa and ...of F. nucleatum in tumors and fecal samples [37] of CRC patients [15, 17, ...
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The FomA Porin from Fusobacterium nucleatum Is a Toll-Like Receptor 2 Agonist with Immune Adjuvant Activity
... Previous studies in the late 1980s, antecedent to identification of TLRs, reported immune adjuvant activity of FomA in a mouse model of immunization with sheep red blood cells (SRBCs) (62). This work suggested that the ...
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Inflammatory Bacteriome Featuring Fusobacterium nucleatum and Pseudomonas aeruginosa Identified in Association with Oral Squamous Cell Carcinoma
... 11 In conclusion, a distinct bacteriome, compositionally and functionally, is associated with OSCC in these Yemeni patients. This study provides the first epidemiological evidence for association of F. ...
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Immunogenicity of a Fap2 peptide mimotope of Fusobacterium nucleatum and its potential use in the diagnosis of colorectal cancer
... that F. nucleatum proteins in- duce lymphocyte ...of F. nucleatum cells in CRC cases was observed to be inversely associated with the density of CD3 + ...of F. nucleatum outer ...
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Identification of a highly active tannase enzyme from the oral pathogen Fusobacterium nucleatum subsp. polymorphum
... The search for new tannase enzymes with improved activity and new substrate specificities constitutes a permanent focus for industrial microbiology research due to their extensive use in the food and pharmaceuti- cal ...
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Coaggregation of Candida dubliniensiswith Fusobacterium nucleatum
... that F. nucleatum possesses a protein receptor and the ...on F. nucleatum. Inhibition of CoAg of F. nucleatum strains among certain gram-negative microorgan- isms has involved a ...
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Combined antioxidant effects of Neem extract, bacteria, red blood cells and Lysozyme: possible relation to periodontal disease
... Fusobacterium nucleatum, and its antioxidant capacities alone and in combination with bacteria and polycationic peptides that may be at the site of ...and F. nucleatum under anaerobic conditions in ...
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Fusobacterium nucleatum in Periodontal Health and Disease
... actinomycetemcomitans, F. nucleatum, Porphyromonas gingivalis, and Peptostreptococcus ...as F. nucleatum, are different; important concentrations are necessary to inhibit growth of some ...
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Thoracic Vertebral Actinomycosis: Actinomyces israelii and Fusobacterium nucleatum
... Fusobacterium nucleatum contributed to the infection or the role of this anaerobe in the pathogenesis of ...consider F. nucleatum as a potential copathogen when treatment is considered ...
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Omega-3 fatty acids suppress Fusobacterium nucleatum–induced placental inflammation originating from maternal endothelial cells
... For in vivo testing, pregnant mice were orally gavaged with fish oil as a source of omega-3 fatty acids throughout the gestation until they were injected with F. nucleatum. The fetal and neonatal death rate ...
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The association between Fusobacterium nucleatum Outer Membrane Vesicles and Colonic Cancer
... both F. nucleatum and OMV elicit cellular responses commensurate with the initiation of EMT and most notably by the increased nuclear localisation of the transcription factor ZEB-1 in addition to the ...
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Distinct microbes, metabolites, and ecologies define the microbiome in deficient and proficient mismatch repair colorectal cancers
... As sulfidogenic F. nucleatum and F. periodonticum were also significantly enriched in dMMR tumor samples, we decided to assess potential hydrogen sulfide production across groups (dMMR/pMMR, ...
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