factor XIII
Factor XIII Val34Leu polymorphism, factor XIII antigen levels and activity and the risk of deep venous thrombosis
... Individuais with the factor XIII 34Leu allele had a higher factor XIII dissociation mdex under conditions of controlled m vitro activation of factor XIII These results mdicate that, unde[r] ...
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Cleavage of blood coagulation factor XIII and fibrinogen by thrombin during in vitro clotting
... coagulation Factor XIII (a2b2) and fibrinogen was studied during in vitro clotting to determine the physiologic sequence of these ...of Factor XIII was measured in platelet-rich ...
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Recombinant [gamma prime] fibrinogen and its interaction with factor XIII
... of factor XIII activation when it is bound to fibrin [4], [5], [6], [7], ...from factor XIII is faster when fibrinogen is included in the reaction mixture, and that FpA is likely cleaved ...
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Free oscillation rheometry monitoring of haemodilution and hypothermia and correction with fibrinogen and factor XIII concentrates
... The findings of this study emphasise the importance of reversing hypothermia and avoiding haemodilution. As previously concluded, it is reasonable to avoid HES in cases of major haemorrhages. Our study showed that the ...
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SURVEY THE MUTATION OF FGB (BETA FIBRINOGEN) AND FV (FACTOR V LEIDEN), FACTOR XIII AND FACTOR II (PROTHROMBIN), IN PATIENTS WITH RECURRENT ABORTIONS ALONG WITH NORMAL KARYOTYPEMaryam Hosseini Moghadam, Pegah Larki, Jafar Panahi, Niloofar Mojtahedifard, Abbas Shakoori*DOWNLOAD/VIEW
... of Factor V Leiden [15, 16 and 17]. The Factor V Leiden causes increasing in abortion and end of pregnancy 2 to 3 ...Coagulation factor XIII is a proenzyme that has transglutaminase ...This ...
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Recombinant factor XIII and congenital factor XIII deficiency: an update from human and animal studies
... Abstract: Factor XIII (FXIII) is a protransglutaminase composed of two catalytic A subunits and two carrier B ...virus-inactivated factor XIII concentrate is the treatment of ...
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The effect of blood coagulation factor XIII on fibrin clot structure and fibrinolysis
... Human fibrinogen, human glu-plasminogen, horse radish peroxidase conjugated (HRP) antibodies to factor XIII-A (SAF-13 HRP) and 2 -antiplasmin (A2AP HRP) were purchased from Enzyme Research Laboratories ...
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The role of β‐barrels 1 and 2 in the enzymatic activity of factor XIII A‐subunit
... length factor XIII A subunit (FXIII-A) and the truncations TCC (both β- barrels removed) and TB1 (β-barrels 2 removed) all retained secondary and tertiary structure, thus the β-barrels are not required to ...
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The role of β‐barrels 1 and 2 in the enzymatic activity of factor XIII A‐subunit
... Summary. Background: Factor XIII is composed of an activation peptide segment, a b-sandwich domain, a cat- alytic core, and, finally, b-barrels 1 and 2. FXIII is acti- vated following cleavage of its ...
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Catridecacog: a breakthrough in the treatment of congenital factor XIII A-subunit deficiency?
... perioperative factor XIII activity levels and other haemostatic markers with the risk of postoperative intracranial haematoma in a selected cohort of neurosurgical ...
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Coagulation factor XIII polymorphisms and the risk of myocardial infarction and ischaemic stroke in young women
... The Tyr204Phe polymorphism of factor XIIIA results in reduced factor XIII specific flbnn cross-lmking activity dnd has been associated with increased risk of recurrent miscarriage (Anwar[r] ...
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Revisiting the mechanism of coagulation factor XIII activation and regulation from a structure/functional perspective
... The activation and regulation of coagulation Factor XIII (FXIII) protein has been the subject of active research for the past three decades. Although discrete evidence exists on various aspects of FXIII ...
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Localization of the gene for coagulation factor XIII a chain to chromosome 6 and identification of sites of synthesis
... the Factor XIII a-chain, cDNA was cloned from a lambda gt11 human placental cDNA ...platelet Factor XIII a-chains confirmed the authenticity of the lambda gt11 ...for Factor XIII ...
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Molecular Imaging of Factor XIII Activity for the Early Detection of Mouse Coronary Microvascular Disease
... Endothelial dysfunction at the early stages and arteriole medial hyperplasia at the late stages are thought to contribute to the development of angina in patients with coronary MVD (7). Such changes may be directly ...
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Correction of hypothermic and dilutional coagulopathy with concentrates of fibrinogen and factor XIII: an in vitro study with ROTEM
... has been studied extensively with whole blood viscoelastic haemostatic assays (VHA) such as thromboelastometry (ROTEM), but there are few studies of simultaneous hypothermia and haemodilution [4,5]. In addition, in vitro ...
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Activation peptide of the coagulation factor XIII (AP-F13A1) as a new biomarker for the screening of colorectal cancer
... Interestingly, identified peptides were found to represent the region of the activation peptide of the coagulation factor XIII A chain (F13A1), also known as the transglutaminase A c[r] ...
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Cre/lox Studies Identify Resident Macrophages as the Major Source of Circulating Coagulation Factor XIII-A
... coagulation factor XIII-A with Golgi proteins within mono- cyte-macrophages: implications for subcellular trafficking and ...É. Factor XIII: a ...
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Factor XIII A-Subunit V34L Variant Affects Thrombus Cross-Linking in a Murine Model of Thrombosis
... Coagulation factor XIII (FXIII) is a protransglutaminase consisting of two A-subunits, and two B-subunits which act as carrier for the A-subunits in plasma 1 ...
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Factor XIII A-Subunit V34L Variant Affects Thrombus Cross-Linking in a Murine Model of Thrombosis
... Coagulation factor XIII (FXIII) is a protransglutaminase consisting of two A-subunits, and two B-subunits which act as carrier for the A-subunits in plasma 1 ...
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Factor XIII A-Subunit V34L Variant Affects Thrombus Cross-Linking in a Murine Model of Thrombosis
... This is a repository copy of Factor XIII A-Subunit V34L Variant Affects Thrombus Cross-Linking in a Murine Model of Thrombosis.. White Rose Research Online URL for this paper: http://epr[r] ...
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