Familial combined hyperlipidemia
Impaired activation of adipocyte lipolysis in familial combined hyperlipidemia
... of familial combined hyperlipidemia (FCHL) is unknown, but altered lipid turnover in peripheral tissues as well as hepatic overproduction of apolipoprotein B have been suggested as possible ...
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Impaired fatty acid metabolism in familial combined hyperlipidemia A mechanism associating hepatic apolipoprotein B overproduction and insulin resistance
... To establish whether insulin resistance and/or postprandial fatty acid metabolism might contribute to familial combined hyperlipidemia (FCH) we have examined parameters of insulin resistance and ...
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Complex genetic contribution of the Apo AI CIII AIV gene cluster to familial combined hyperlipidemia Identification of different susceptibility haplotypes
... Familial combined hyperlipidemia (FCH) is a common ge- netic lipid disorder in Western societies. In a recent report (Dallinga-Thie, G.M., X.D. Bu, M. van Linde-Sibenius Trip, J.I. Rotter, A.J. ...
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Factors associated with postprandial lipemia and apolipoprotein A-V levels in individuals with familial combined hyperlipidemia
... FCH: Familial combined hyperlipidemia; iAUC: Incremental area under the curve; WHR: Waist to hip ratio; TRL: Triglycerides rich lipoproteins; CVD: Cardiovascular disease; VLDL: Very low density ...
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Small and dense LDL in familial combined hyperlipidemia and N291S polymorphism of the lipoprotein lipase gene
... Familial Combined Hyperlipidemia (FCH; MIM 144250) is the most frequent genetic hyperlipemia. It is characterized by a tendency towards the appearance of coronary disease before 60 years of age [4]. ...
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Resolving the Genetic Etiology of Hypercholesterolemia in Familial Combined Hyperlipidemia
... Negative Familial Hypercholesterolemia (FH/M-) patients (cases) and 44 Mutation Positive Familial Hypercholesterolemia (FH/M+) patients (age- and sex-matched controls) were ...
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Lipoprotein lipase modulates net secretory output of apolipoprotein B in vitro A possible pathophysiologic explanation for familial combined hyperlipidemia
... We showed previously that net secretory output of apolipoprotein B (apo B) from cultured human hepatoma cells (HepG2) is regulated by rapid reuptake of nascent lipoproteins before they have diffused away from the ...
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Association of TCF7L2 Gene with Familial Combined Hyperlipidemia in Diabetes Mellitus Type 2 Females Iraqi Patients
... Genomic polymorphisms of transcription factor7 like 2 {TCF7L2} gene are scanned to be powerfully related to diabetes mellitus type 2 (DM2) in female Iraqi population. The point of this examination was to break down the ...
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Vitamin D concentrations in familial combined hyperlipidemia: effects of lipid lowering treatment
... pleiotropic properties of statins and independently of their intrinsic effect on serum lipids [34-38]. Information regarding the effect of lipid-lowering drugs other than statins is scarce but ezetimibe and fibrates ...
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The lipoprotein lipase gene in combined hyperlipidemia: evidence of a protective allele depletion
... Though over 200 coding mutations within the LPL gene (MIM 609708) have been described, the role for common functional polymorphism of LPL, particularly in familial combined hyperlipidemia (FCH [MIM ...
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Hyperlipidemia in Coronary Heart Disease II GENETIC ANALYSIS OF LIPID LEVELS IN 176 FAMILIES AND DELINEATION OF A NEW INHERITED DISORDER, COMBINED HYPERLIPIDEMIA
... of hyperlipidemia identified in this study has hitherto been poorly defined and has been designated as familial combined ...The combined disorder was shown to be genetically distinct from ...
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Incidence of pancreatitis, secondary causes, and treatment of patients referred to a specialty lipid clinic with severe hypertriglyceridemia: a retrospective cohort study
... Figure 1 Triglycerides, Total Cholesterol, and Total Cholesterol:HDL-C Ratio at Initial and Latest Clinic Visit in HTG Patients.. familial combined hyperlipidemia and is not routinely av[r] ...
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Original Article Serum lipid levels and the risk factors in the Mulao and Han ethnic groups
... and hyperlipidemia was also higher in Mulao than in Han ...of hyperlipidemia was positively correlated with BMI, hypertension and the intakes of total energy and total fat in Han, whereas it was positively ...
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Uncharted waters: rare and unclassified cardiomyopathies characterized on cardiac magnetic resonance imaging
... Dublin 4, Ireland.. 11 , 12 ) Familial Familial, unknown gene Familial, unknown gene Familial, unknown gene Familial, unknown gene Familial, unknown gene Sarcomeric protein mutations Sar[r] ...
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Cobalamin C Defect Presenting With Isolated Pulmonary Hypertension
... lesions combined with a familial history of hemolytic uremic syndrome in the elder brother prompted us to suspect cblC defect (which had not been considered before in the differen- tial diagnosis of his ...
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CLINICAL EFFICACY OF ATASI (Linum usitatissimum) IN MEDOROGA .......
... same as of medas. Here Medoroga can be termed as Hyperlipidemia. urveda for the treatment of Medoroga. the magnitude of Hyperlipidemia in causing life threatening diseases, the present[r] ...
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“Evaluation of Clarithromycin Availability at Intestine and Liver in Rat after Induction of Hyperlipidemia by High Fat Diet and Comparison with Non-Hyperlipidemia” by K. Prasanna Kumar, Y. Narsimha Reddy, India.
... here is an epidemic of overweight and metabolic syndrome worldwide and consequently there is increasing medical focus on the issue of hyperlipidemia. Studies have documented the increasing prevalence of overweight ...
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Ratio of apoB/LDL: a potential clinical index for vascular cognitive impairment
... of hyperlipidemia in the dementia group was lower than that in the infarction group; although, this does not prove that hyperlipidemia is a protective factor for vas- cular dementia, considered together ...
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Novel AE1 mutations in recessive distal renal tubular acidosis Loss of function is rescued by glycophorin A
... of familial dRTA with cosegregating AE1 mutations have been restricted thus far to cohorts displaying an autoso- mal dominant inheritance pattern, the combined erythroid and renal phenotype in this family ...
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Increased dementia risk predominantly in diabetes mellitus rather than in hypertension or hyperlipidemia: a population-based cohort study
... and hyperlipidemia remained ...or hyperlipidemia on dementia following the DM ...and hyperlipidemia to examine the pathogenesis underlying the dementia risk in patients with and without ...
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