Fas / Fas ligand
The expression of Fas Ligand by macrophages and its upregulation by human immunodeficiency virus infection
... Fas/Fas Ligand (FasL) interactions play a significant role in peripheral T lymphocyte homeostasis and in certain patho- logical states characterized by T cell ...
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Neutrophil Suppresses Tumor Cell Proliferation via Fas /Fas Ligand Pathway Mediated Cell Cycle Arrested
... with Fas antagonist and a slight increase was observed in Fas agonist treated tumor ...of Fas-knock out A549 cells was partially restored when co-culture with neutrophils ...stimulated ...
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Herpes simplex virus type 2 inhibition of Fas ligand expression.
... the Fas apoptotic pathway as an antiviral mech- anism. The inhibition of Fas ligand surface expression by HSV-2 suggests that the Fas-Fas ligand interaction plays a role in the ...
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Tumor necrosis factor-alpha and Fas/Fas ligand signaling pathways in chronic spontaneous urticaria
... and Fas/ Fas ligand (FasL) in the apoptosis‑inducing pathways in chronic spontaneous urticaria (CSU), remain ...soluble Fas (sFas) and FasL (sFasL) in CSU ...
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Decitabine immunosensitizes human gliomas to NY ESO 1 specific T lymphocyte targeting through the Fas/Fas Ligand pathway
... of Fas and possibly other death receptors [38]. Fas/FasL is an extrinsic death pathway that induces apoptosis upon tri- merization of Fas after binding to FasL leading to the recruitment of ...
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Amelioration of collagen induced arthritis by CD95 (Apo 1/Fas) ligand gene transfer
... encoding Fas or FasL lead to lymphocytic proliferation and autoimmune in- flammatory diseases ...(3–5). Fas is expressed constitutively in most tissues (5) and is dramatically upregulated at the site of ...
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Mesenchymal stem cells inhibit multiple myeloma cells via the Fas/Fas ligand pathway
... cells. Fas (DR2/CD95/Apo-1) is a type I cell membrane protein with an extracellular domain that binds Fas ligand (Fas-L) and a cytoplasmic domain that transduces the death signal ...[19,20]. ...
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Status of FAS and FAS Ligand Gene Polymorphisms in Patients wi th Breast Cancer in Northeastern IRAN
... L. FAS and FAS- Ligand Promoter Polymorphisms in Hepatitis B Virus ...al. FAS promoter polymorphisms and cancer risk: a meta-analysis based on 34 case– control ...of FAS and FASL gene ...
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Elimination of rheumatoid synovium in situusing a Fas ligand 'gene scalpel'
... Surgical synovectomy to remove the inflammatory synovium can temporarily ameliorate rheumatoid inflammation and delay the progress of joint destruction. An efficient medically induced programmed cell death (apoptosis) in ...
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Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes A potential role for the acidic sphingomyelinase pathway in normal immunoregulation
... express Fas, together with the marker of progress activation ...expressed Fas ligand (FasL), perhaps as a result of recent in vivo ...whereas Fas cross-linking did not result in apoptosis ...
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Soluble Fas ligand inhibits angiogenesis in rheumatoid arthritis
... pannus. Fas ligand is critical to the homeostatic regulation of the immune response, but its role in the angiogenic process of RA remains to be ...soluble Fas ligand (sFasL) induces ...
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Proinflammatory consequences of transgenic Fas ligand expression in the heart
... of Fas ligand (FasL) renders certain tissues immune privileged, but its expression in other tissues can result in severe neutrophil infiltration and tissue ...of Fas and FasL in Tg hearts, neither ...
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Antigen presenting cells expressing Fas ligand down modulate chronic inflammatory disease in Fas ligand–deficient mice
... that Fas-FasL interactions are required for down- modulation of an inflammatory response after the clearance of ...of Fas, as the inflam- matory response in MCMV-infected B6-lpr/lpr mice (18) cannot be ...
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Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease
... genes, fas and fas ligand ( fasL ), are candidate contributory genes in human SLE, as mutations of these genes result in autoim- munity in several murine models of this ...humans, fas ...
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Fas ligand expression by astrocytoma in vivo: maintaining immune privilege in the brain?
... of Fas ligand (FasL/CD95L) by human astrocytoma and the efficient killing of Fas-bearing cells by astrocytoma lines in vitro and by tumor cells ex ...
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γδ T Cells Promote a Th1 Response during Coxsackievirus B3 Infection In Vivo: Role of Fas and Fas Ligand
... soluble Fas (CD95) and Fas ligand (FasL) predict disease course in pa- tients with acute myocarditis, with the highest levels of these factors occurring in patients with a fatal outcome ...(11). ...
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Oxidative stress increases Fas ligand expression in endothelial cells
... soluble Fas ligand retains its capacity to interact with Fas, and serum concen- trations of soluble FasL are related to the development of vascular ...
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Soluble Fas Ligand as a Potential Marker of Severity of Dengue Infection
... the Fas ligand. Monocytes also have Fas receptors, resulting in the apoptosis of monocytes which are infected by ...soluble Fas ligand (10). High levels of soluble Fas ...
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Lack of both Fas Ligand and Perforin Protects from Flavivirus-Mediated Encephalitis in Mice
... of Fas-mediated cytotoxicity in the pathogenesis of mice infected with ...of Fas on the target cell by Fas ligand (FasL) (for a review, see reference ...the Fas gene (lpr) or a point ...
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Posttranslational regulation of Fas ligand function
... member Fas ligand acts as a prototypic death ...in Fas (APO-1, CD95) expressing cells, Fas ligand participates in essential effector functions of the immune ...addition, Fas ...
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