Fas Ligand
Neutrophil Suppresses Tumor Cell Proliferation via Fas /Fas Ligand Pathway Mediated Cell Cycle Arrested
... with Fas antagonist and a slight increase was observed in Fas agonist treated tumor ...of Fas-knock out A549 cells was partially restored when co-culture with neutrophils ...stimulated ...
11
Status of FAS and FAS Ligand Gene Polymorphisms in Patients wi th Breast Cancer in Northeastern IRAN
... L. FAS and FAS- Ligand Promoter Polymorphisms in Hepatitis B Virus ...al. FAS promoter polymorphisms and cancer risk: a meta-analysis based on 34 case– control ...of FAS and FASL gene ...
7
Antigen presenting cells expressing Fas ligand down modulate chronic inflammatory disease in Fas ligand–deficient mice
... and Fas ligand cell-surface expression was characterized by flow cytometry using an anti-FasL antibody (clone Kay-10; PharMingen) as described ...these Fas-deficient murine B6- lpr/lpr APCs were ...
10
Tumor necrosis factor-alpha and Fas/Fas ligand signaling pathways in chronic spontaneous urticaria
... and Fas/ Fas ligand (FasL) in the apoptosis‑inducing pathways in chronic spontaneous urticaria (CSU), remain ...soluble Fas (sFas) and FasL (sFasL) in CSU ...
9
Herpes simplex virus type 2 inhibition of Fas ligand expression.
... assess Fas ligand surface expression, we used a biotinylated mouse monoclonal antibody specific for human Fas ligand, NOK-1 (19), and biotinylated control immuno- globulin G1 (IgG1) antibodies ...
5
Fas ligand mutation in a patient with systemic lupus erythematosus and lymphoproliferative disease
... genes, fas and fas ligand (fasL), are candidate contributory genes in human SLE, as mutations of these genes result in autoimmunity in several murine models of this ...humans, fas mutations ...
8
Lack of both Fas Ligand and Perforin Protects from Flavivirus-Mediated Encephalitis in Mice
... of Fas-mediated cytotoxicity in the pathogenesis of mice infected with ...of Fas on the target cell by Fas ligand (FasL) (for a review, see reference ...the Fas gene (lpr) or a point ...
10
Elimination of rheumatoid synovium in situusing a Fas ligand 'gene scalpel'
... Surgical synovectomy to remove the inflammatory synovium can temporarily ameliorate rheumatoid inflammation and delay the progress of joint destruction. An efficient medically induced programmed cell death (apoptosis) in ...
9
The expression of Fas Ligand by macrophages and its upregulation by human immunodeficiency virus infection
... Fas/Fas Ligand (FasL) interactions play a significant role in peripheral T lymphocyte homeostasis and in certain pathological states characterized by T cell ...
13
Soluble Fas ligand inhibits angiogenesis in rheumatoid arthritis
... pannus. Fas ligand is critical to the homeostatic regulation of the immune response, but its role in the angiogenic process of RA remains to be ...soluble Fas ligand (sFasL) induces ...
9
Proinflammatory consequences of transgenic Fas ligand expression in the heart
... of Fas ligand (FasL) renders certain tissues immune privileged, but its expression in other tissues can result in severe neutrophil infiltration and tissue ...of Fas and FasL in Tg hearts, neither ...
11
γδ T Cells Promote a Th1 Response during Coxsackievirus B3 Infection In Vivo: Role of Fas and Fas Ligand
... soluble Fas (CD95) and Fas ligand (FasL) predict disease course in pa- tients with acute myocarditis, with the highest levels of these factors occurring in patients with a fatal outcome ...(11). ...
8
Decitabine immunosensitizes human gliomas to NY ESO 1 specific T lymphocyte targeting through the Fas/Fas Ligand pathway
... of Fas and possibly other death receptors [38]. Fas/FasL is an extrinsic death pathway that induces apoptosis upon tri- merization of Fas after binding to FasL leading to the recruitment of ...
13
Mesenchymal stem cells inhibit multiple myeloma cells via the Fas/Fas ligand pathway
... cells. Fas (DR2/CD95/Apo-1) is a type I cell membrane protein with an extracellular domain that binds Fas ligand (Fas-L) and a cytoplasmic domain that transduces the death signal ...[19,20]. ...
14
Amelioration of collagen induced arthritis by CD95 (Apo 1/Fas) ligand gene transfer
... encoding Fas or FasL lead to lymphocytic proliferation and autoimmune in- flammatory diseases ...(3–5). Fas is expressed constitutively in most tissues (5) and is dramatically upregulated at the site of ...
8
Functional expression of Fas and Fas ligand on human gut lamina propria T lymphocytes A potential role for the acidic sphingomyelinase pathway in normal immunoregulation
... of Fas (CD95 / APO-1), a cell surface receptor directly responsible for triggering cell death by apoptosis, was investigated on human T lympho- cytes resident within the intestinal lamina propria, a major site of ...
8
Soluble Fas Ligand as a Potential Marker of Severity of Dengue Infection
... soluble Fas ligand was measured using a Quantikine Fas ligand ...of Fas ligand conjugate was added to each well, covered with adhesive strip, and incubated for 1 h at room ...
5
Posttranslational regulation of Fas ligand function
... member Fas ligand acts as a prototypic death ...in Fas (APO-1, CD95) expressing cells, Fas ligand participates in essential effector functions of the immune ...addition, Fas ...
12
Interleukin 10 promotes activation induced cell death of SLE lymphocytes mediated by Fas ligand
... Immune function in SLE is paradoxically characterized by active T cell help for autoantibody production, along with impaired T cell proliferative and cytokine responses in vitro. To reconcile these observations, we ...
13
P2X7 signaling promotes microsphere embolism-triggered microglia activation by maintaining elevation of Fas ligand
... The Fas ligand (FasL)-Fas system may play a role in both physiological and pathological situations in the brain [10,11], whether and how FasL-Fas system influ- ences the pathogenesis of ...
15