Fatty Acid Amide Hydrolase
Fatty acid amide hydrolase shapes NKT cell responses by influencing the serum transport of lipid antigen in mice
... enzyme fatty acid amide hydrolase (FAAH) from mouse serum as an αGalCer- binding protein that modulates the induction of key effector functions of NKT cells in ...
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The fatty acid amide hydrolase inhibitor URB597 exerts anti inflammatory effects in hippocampus of aged rats and restores an age related deficit in long term potentiation
... by fatty acid amide hydrolase (FAAH) and 2-arachido- noylglycerol (2-AG), which is hydrolyzed by FAAH and monoacylglycerol lipase (MAGL) ...
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3D-QSAR on a series of pyrimidinyl-piperazine- carboxamides based Fatty Acid Amide Hydrolase (FAAH) inhibitors as a useful tool to obtain novel endocannabinoid enhancers
... Abstract: Fatty Acid Amide Hydrolase (FAAH) is one of the enzymes responsible of endocannabinoids metabolism. The inhibition of FAAH is a useful and indirect strategy to raise endogenous ...
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Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells
... of fatty acid amide hydrolase (FAAH) which catalyzes the degradation of endocannabinoids (anandamide [AEA], 2-arachidonoylglycerol [2-AG]) and endocannabinoid-like substances ...
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Early blockade of joint inflammation with a fatty acid amide hydrolase inhibitor decreases end stage osteoarthritis pain and peripheral neuropathy in mice
... Background: The endocannabinoid system has been shown to reduce inflammatory flares and pain in rodent models of arthritis. A limitation of endocannabinoids is that they are rapidly denatured by hydrolysing enzymes such ...
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Fatty acid amide hydrolase deficiency limits early pregnancy events
... carbamic acid 3′-carbamoyl-biphenyl-3-yl ester) (25), at a daily dose of 1 mg/kg BW on days 1–3, 75% of them (9 of 12) showed oviductal reten- tion of embryos when examined on day 4 mid-morning (Figure 4, B and ...
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Emmerdinger, Dominik (2009): Die Rolle des Enzyms Fatty Acid Amide Hydrolase (FAAH) und von Varianten des FAAH Gens bei chronisch entzündlichen Darmerkrankungen. Dissertation, LMU München: Medizinische Fakultät
... Da das FAAH Enzym einen derartig wichtigen Baustein im Abbauprozess der Endocannabinoide darstellt, war es unser Bestreben zu untersuchen, ob es einen Zusammenhang [r] ...
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The activity of the endocannabinoid metabolising enzyme fatty acid amide hydrolase in subcutaneous adipocytes correlates with BMI in metabolically healthy humans
... In one study, MGL mRNA in omental and subcutaneous adipose tissue was compared between distinct cohorts of lean and obese humans and it was found that in omental adipose, MGL mRNA was de[r] ...
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Defects in fatty acid amide hydrolase 2 in a male with neurologic and psychiatric symptoms
... Additional file 2: Figure S1. Sequence comparison of selected amidase signature family members. The sequences of Bacillus subtilis Glu-tRNAGln amidotransferase subunit A, Pseudomonas putida mandelamide hydrolase, ...
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Morinda citrifolia (Noni) Fruit Juice Inhibits Endocannabinoid Degradation Enzymes
... arachidonic acid derivatives, N-arachidonoyl phosphatidylethanolamine (NAPE) and diacylglycerol, by phospholipases and diacylglycerol ...by fatty acid amide hydrolase (FAAH) to ...
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Adipose tissue endocannabinoid system gene expression: depot differences and effects of diet and exercise
... The purpose of this study was to determine whether gene expression levels of cannabinoid type 1 receptor (CB1) and fatty acid amide hydrolase (FAAH) are different in subcutaneous abdomin[r] ...
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An engineered fatty acid synthase combined with a carboxylic acid reductase enables de novo production of 1-octanol in Saccharomyces cerevisiae
... for fatty alcohol production has a BY background and is based on ...the fatty acyl-CoA synthetase Δfaa2 was gener- ated using the CRISPR–Cas9 system ...
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Studies in the Ketosis of Fasting
... in fatty acid mobilization from the periphery, fatty acid oxidation, fatty acid synthesis, or the acetyl coenzyme A concentration in the ...
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Degradation of selected nutrients in sunflower oils during long term storage
... oleic acid as the main component compared to oils that contain a higher amount of linoleic acid (Velíšek ...the fatty acid composition but at a higher content they have a pro-oxidative ...
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Journal of Applied Pharmaceutical Science
... The fatty acids esterified to the triglycerides were deduced to be oleic acid, linoleic acid and linolenic ...Oleic acid has been reported to be responsible for the reduction of blood pressure ...
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FATTY ACID PROFILING IN DIPLOID (n = 12) AND TETRAPLOID CYTOTYPES (n = 24) OF PHYSALIS ANGULATA LINN FROM RAJASTHAN BY GAS CHROMATOGRAPHY
... Preparation of Methy-esters of Fatty Acids: Trans-methy mixture was prepared by mixing 150ml of methanol and 70ml of toluene and adding 7.5 ml of concentrated sulphuric acid. 10-12mg of fat was added to ...
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Original Article Asiatic acid promotes liver fatty acid metabolism in diabetic models
... Asiatic acid (AA) has lipid-lowering and anti-diabetic ...liver fatty acid ...free fatty acid (FFA)-induced hepatic cell ...with fatty acid synthesis and increased ...
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Fatty Acids Profiles of Stipe and Blade from the Norwegian Brown Macroalga Laminaria hyperborea, Using Off-Line SPE and GC-MS
... A split ratio of 1:10 was used with injections of 1 µL sample. Two injections parallels were used for each sample replicate. Identification of fatty acids was performed by comparing retention times with standards ...
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SYNTHESIS OF AMIDE-BASED SURFACTANTS FROM FATTY ACID METHYL ESTER: EFFECT OF SOLVENT RATIO AND STIRRING SPEED
... lauric acid, which is converted to monoglyceride called monolaurin; 16-11% myristic acid which is a saturated fatty acid; 5- 10% caprylic acid and other components such as palmitic ...
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Effects of enriched Artemia with n–3 long-chain polyunsaturated fatty acids on growth performance, stress resistance and fatty acid profile of Litopenaeus vannamei postlarvae
... contained fatty acid methyl esters was separated, and then evaporated under a stream of ...dry fatty acid methyl esters were dissolved in isooctane (1 ml) and determined by gas chromatography, ...
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