Fe/sub 3/B
Synergistic effect of a combination of nanoparticulate Fe<sub>3</sub>O<sub>4</sub> and gambogic acid on phosphatidylinositol 3-kinase/Akt/Bad pathway of LOVO cells
... containing Fe 3 O 4 had a normal healthy shape, as demonstrated by their clear cytoskeletons (Figure 3A and ...containing Fe 3 O 4 with or without ...the Fe 3 O 4 magnetic ...
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Synergistic effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> with gambogic acid on apoptosis of K562 leukemia cells
... κ B, and survivin, we next performed Western blot analysis on whole cell protein extracted from cells treated for 48 hours as described ...κ B, surviving, or β -actin anti-body in 5% nonfat dry milk, and ...
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Magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> enhance docetaxel-induced prostate cancer cell death
... κ B [NF κ B]; 1:10,000 for β -actin) for 1 hour at room ...κ B and β -actin were purchased from Santa Cruz Biotechnology, Inc (Santa Cruz, CA, USA) and Sigma- Aldrich, respectively; antirabbit and ...
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Multifunctional magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles combined with chemotherapy and hyperthermia to overcome multidrug resistance
... the Fe 3 O 4 -MNP-DNR-5-BrTet and Fe 3 O 4 -MNP groups; karyopyknosis and karyorrhexis could be observed in the apoptotic cells, especially in the Fe 3 O 4 -MNP-DNR-5-BrTet ...
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Magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and chemotherapy agents interact synergistically to induce apoptosis in lymphoma cells
... κ B might help circumvent resistance to conventional ...κ B protein. Interestingly, in the present study, MNP-Fe 3 O 4 combined with adriamycin or daunorubicin increased upregulation of p53 ...
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Preparation and in vitro evaluation of doxorubicin-loaded Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles modified with biocompatible copolymers
... the Fe 3 O 4 -PLGA-PEG nanoparticles was also pH-dependent and enhanced at pH ...hydrophilic B blocks (central ...the Fe 3 O 4 -PLGA-PEG nanoparticles by a diffusion mechanism in ...
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Effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and wogonin on the reversal of multidrug resistance in K562/A02 cell line
... After incubating with 0.1 (v/v) magnetic nanoparticles for 48 hours at 37 ° C, the cells were harvested and made into cell smears. Before observation by optical microscopy, the cells were stained with Prussian blue. The ...
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Effects of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> combinated with gambogic acid on apoptosis of SMMC-7721 cells
... HCC is the most common type of liver cancer. It is the third leading cause of cancer-related death globally. Most cases of HCC are secondary to either a viral hepatitis infection (hepatitis B or C) or cirrhosis. ...
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Co-encapsulation of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and doxorubicin into biodegradable PLGA nanocarriers for intratumoral drug delivery
... labeled Annexin V (Annexin V-FITC) and propidium (PI) double staining and flow cytometry were used to determine the proportion of live cells (Annexin V-FITC and PI double negative, bottom left quadrant), early apoptotic ...
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The reversal effect of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles loaded with cisplatin on SKOV3/DDP ovarian carcinoma cells
... MNPs-Fe 3 O 4 , (b) DDP, (c) MNPs- Fe 3 O 4 , (d) RPMI-1640 for 48 h, and ...for 3 min and 35 cycles of 95 ° C for 30 s, 56 ° C for 30 s, and 72 ° C for 1 ...
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Fe and Co doped (Ba, Ca)TiO<sub>3</sub> Perovskite as Potential Electrocatalysts for Glutamate Sensing
... at% Fe and Co powders were successfully synthesized by a solution combustion ...of Fe and Co doping on phase homogeneity, microstructure, and bandgap energy were ...that Fe-doped BaTiO 3 , Co ...
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Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... All animals were kept in stress-free, hygienic, and animal- friendly conditions (relative humidity 60% ± 10%, room tem- perature 20 ° C ± 2 ° C, and 12-hour light/dark cycle). Food and water were available ad libitum. ...
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Fe<sub>3</sub>O<sub>4</sub>/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein
... labeling Fe 3 O 4 /Au strategy as part of a signal amplification procedure and demonstrated its use in the ultrasensitive, selective, and accurate quantification of AFP by electrochemical immunoas- ...are: ...
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In vitro toxicity of Fe<sub>m</sub>O<sub>n</sub>, Fe<sub>m</sub>O<sub>n</sub>-SiO<sub>2</sub> composite, and SiO<sub>2</sub>-Fe<sub>m</sub>O<sub>n</sub> core-shell magnetic nanoparticles
... All chemicals were purchased from Sigma-Aldrich (St Louis, MO, USA). Bare IONPs were synthesized by coprecipitation of ferrous and ferric iron ion solutions. Briefly, the mixture of 25% NH 4 OH and 1% ammonium acetate ...
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Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... of Fe 3 O 4 -magnetic nanoparticles (MNPs-Fe 3 O 4 ) on the expression of KCNQ 1 in cardiac muscle of mice at rest and at different times following a single bout of swimming ...MNPs-Fe ...
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Inhibitory effect of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles coloaded with homoharringtonine on human leukemia cells in vivo and in vitro
... As shown in Figure 1A, the polymeric micelles were gener- ated by the hydrophobic interaction of the polyoxyethylene– polyoxypropylene copolymer chain and oleic acid on the surface of iron oxide NPs. The average core ...
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Characteristics of magnetic labeling on liver tumors with anti-alpha-fetoprotein-mediated Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... For these MFs, the hydrodynamic diameters of MNPs, as well as the MNPs with anti-AFP and anti-CEA coating, are 57.3 ± 15.2 nm, 54.3 ± 10.1 nm, and 54.4.0 ± 10.5 nm, respec- tively (Figure 2A). The measured saturation ...
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Ultrasmall superparamagnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles: honey-based green and facile synthesis and in vitro viability assay
... the Fe 3 O 4 -NPs are spherical with a diameter range between ...of Fe 3 O 4 -NPs performed by using the MTT assay on the WEHI164 cells demonstrated no significant toxicity in higher ...
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Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>@Au composite magnetic nanoparticles in vitro and in vivo
... that Fe 3 O 4 @Au composite MNPs were almost ingested and deposited in the liver because no nanoparticles and hemosiderosis were observed in other organs including heart, spleen, lung, kidney, and brain, ...
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Fe<sub>3</sub>O<sub>4</sub>-based PLGA nanoparticles as MR contrast agents for the detection of thrombosis
... agent Fe 3 O 4 with a PLGA- and cRGD-based delivery system to synthesize NPs in this study did not increase ...within 3 h and returned to normal values after 24 h; we thus determined that, despite ...
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