Fe/sub 3/O/sub 4/(110)
The reversal effect of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles loaded with cisplatin on SKOV3/DDP ovarian carcinoma cells
... proteins are associated with a poor prognosis in patients with ovarian cancer. P-gp and MDR protein (MRP) are known to be associated with MDR. P-gp, an integral membrane glycoprotein with a molecular mass of 170 kd, has ...
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Biosafety evaluation of Janus Fe<sub>3</sub>O<sub>4</sub>-TiO<sub>2</sub> nanoparticles in Sprague Dawley rats after intravenous injection
... and Fe) was detected by inductively coupled plasma (ICP) mass spectrometry (MS; Nexion 300D; PerkinElmer ...caspase 3, Bcl2, Bax, p50, p53, Nrf2, Akt, and GAPDH were obtained from Cell Signaling Technology ...
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Effects of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> combinated with gambogic acid on apoptosis of SMMC-7721 cells
... that Fe 3 O 4 -MNP at less than 20 μ g/mL concen- tration had no obviously effect on SMMC-7721 prolif- eration ...g/mL Fe 3 O 4 -MNP with different con- centrations ...
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Ultrasmall superparamagnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles: honey-based green and facile synthesis and in vitro viability assay
... the Fe 3 O 4 -NPs are spherical with a diameter range between ...of Fe 3 O 4 -NPs performed by using the MTT assay on the WEHI164 cells demonstrated no significant ...
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Effect of Fe<sub>3</sub>O<sub>4</sub>-magnetic nanoparticles on acute exercise enhanced KCNQ<sub>1</sub> expression in mouse cardiac muscle
... of Fe 3 O 4 -magnetic nanoparticles (MNPs-Fe 3 O 4 ) on the expression of KCNQ 1 in cardiac muscle of mice at rest and at different times following a single bout of ...
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Biocompatibility of Fe<sub>3</sub>O<sub>4</sub>@Au composite magnetic nanoparticles in vitro and in vivo
... that Fe 3 O 4 @Au composite MNPs were almost ingested and deposited in the liver because no nanoparticles and hemosiderosis were observed in other organs including heart, spleen, lung, kidney, ...
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Synergistic effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> with gambogic acid on apoptosis of K562 leukemia cells
... MNPs-Fe 3 O 4 induced apoptosis not only through influencing the regulatory factors in the intrinsic mitochondrial pathway such as bax and bcl-2, but also through regulating the transcription ...
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Magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and chemotherapy agents interact synergistically to induce apoptosis in lymphoma cells
... (MNP-Fe 3 O 4 ) and chemotherapeutic drugs on lymphoma ...MNP-Fe 3 O 4 ...MNP-Fe 3 O 4 with adriamycin or daunorubicin increased p53 ...
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Inhibitory effect of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles coloaded with homoharringtonine on human leukemia cells in vivo and in vitro
... As shown in Figure 1A, the polymeric micelles were gener- ated by the hydrophobic interaction of the polyoxyethylene– polyoxypropylene copolymer chain and oleic acid on the surface of iron oxide NPs. The average core ...
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In vitro toxicity of Fe<sub>m</sub>O<sub>n</sub>, Fe<sub>m</sub>O<sub>n</sub>-SiO<sub>2</sub> composite, and SiO<sub>2</sub>-Fe<sub>m</sub>O<sub>n</sub> core-shell magnetic nanoparticles
... uncoated, Fe m O n -SiO 2 composite flake-like, and SiO 2 -Fe m O n core-shell IONPs on cell viability, function, and mor- phology were tested 48 h postincubation in human umbilical vein ...
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Fe<sub>3</sub>O<sub>4</sub>/Au magnetic nanoparticle amplification strategies for ultrasensitive electrochemical immunoassay of alfa-fetoprotein
... HAuCl 4 solution containing ...in 3% bovine serum albumin and phosphate-buffered solution at 37 ° C for one hour to block excess active groups and nonspecific binding sites on the ...
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The effects of magnetite (Fe<sub>3</sub>O<sub>4</sub>) nanoparticles on electroporation-induced inward currents in pituitary tumor (GH<sub>3</sub>) cells and in RAW 264.7 macrophages
... of Fe 3 O 4 NPs on I MEP , we studied whether the nanoparticles could alter the I MEP measured at the different levels of membrane potentials in these ...of Fe 3 O ...
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Magnetic nanoparticle of Fe<sub>3</sub>O<sub>4</sub> and 5-bromotetrandrin interact synergistically to induce apoptosis by daunorubicin in leukemia cells
... MNP(Fe 3 O 4 ) and BrTet to sensitize MDR cells to anticancer agents in vitro and determine their combination effects on apoptosis induced by combining DNR in leukemic ...MNP(Fe ...
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Immobilized transferrin Fe<sub>3</sub>O<sub>4</sub>@SiO<sub>2</sub> nanoparticle with high doxorubicin loading for dual-targeted tumor drug delivery
... DMP was suspended in 10 mL phosphate-buffered saline (PBS) solution, and incubated with 5 mg EDC and 5 mg NHS for 30 minutes at room temperature. Then, the products were separated using magnetic separation and ...
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Effect of magnetic nanoparticles of Fe<sub>3</sub>O<sub>4</sub> and wogonin on the reversal of multidrug resistance in K562/A02 cell line
... After treatment as before, total protein was isolated on ice and subjected to 10% sodium dodecyl sulfate polyacrylamide gel electrophoresis using a modified radioimmunoprecipitation assay buffer, and then transferred to ...
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Characteristics of magnetic labeling on liver tumors with anti-alpha-fetoprotein-mediated Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles
... Abstract: For preoperative and intraoperative detection of tumor distribution, numerous multi- modal contrast agents, such as magnetic nanoparticles (MNPs) with several examination indicators, are currently in ...
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Co-encapsulation of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and doxorubicin into biodegradable PLGA nanocarriers for intratumoral drug delivery
... Abstract: In this study, the authors constructed a novel PLGA [poly(D,L-lactic-co-glycolic acid)]-based polymeric nanocarrier co-encapsulated with doxorubicin (DOX) and magnetic Fe 3 O 4 ...
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Biocompatibility of magnetic Fe<sub>3</sub>O<sub>4</sub> nanoparticles and their cytotoxic effect on MCF-7 cells
... of Fe 3 O 4 nano magnetofluid ...g/L Fe 3 O 4 ), and a simple magnetic field irradiation group (a negative control group plus magnetic field ...and 4 kW with ...
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Preparation of Fe<sub>3</sub>O<sub>4</sub> magnetic nanoparticles coated with gallic acid for drug delivery
... different pH levels which are similar to the pH of the stomach and the pH of the blood. Generally, the pH of the stomach varies from 1–2 to 4–5. After eating, the stomach releases proteases and hydrochloric acid ...
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Fe<sub>3</sub>O<sub>4</sub>-based PLGA nanoparticles as MR contrast agents for the detection of thrombosis
... = 4). Then, Fe 3 O 4 -PLGA or Fe 3 O 4 -PLGA-cRGD NPs at a final dosage of 1 mg lyophilized powder dissolving 1 mL phosphate- buffered saline (PBS) was ...
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