Feline Calicivirus
In vitro antiviral activity and kinetics of the inhibitory effect of some compounds against Feline calicivirus strain F9 – a surrogate model of human noroviruses
... At present, there are not enough data published in the scientific literature for the specific treatment and prevention of the infections caused by caliciviruses, respectively noroviruses. Also little is known about the ...
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Entry of Feline Calicivirus Is Dependent on Clathrin-Mediated Endocytosis and Acidification in Endosomes
... Feline calicivirus is a major causative agent of respiratory disease in cats. It is also one of the few cultivatable members of Caliciviridae. We have examined the entry process of feline ...
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The Capsid Gene of Feline Calicivirus Contains Linear B-Cell Epitopes in both Variable and Conserved Regions
... Feline calicivirus (FCV) is an important acute, oral and respiratory pathogen of domestic cats (13) and belongs to the family Caliciviridae (6). It contains a single-stranded, positive- sense RNA genome of ...
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Longitudinal Molecular Epidemiological Analysis of Feline Calicivirus Infection in an Animal Shelter: a Model for Investigating Calicivirus Transmission within High Density, High Turnover Populations
... of calicivirus infection in high-density, high-throughput populations is a challenge to both human and veterinary ...of feline calicivirus (FCV) infection in an animal rescue shelter can be used as a ...
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Junctional Adhesion Molecule 1 Is a Functional Receptor for Feline Calicivirus
... of calicivirus is not fully understood because most of the viruses cannot be propagated in tissue culture ...of calicivirus entry into cells using feline calicivirus (FCV), a cultivable ...
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Large-Scale Spatial and Temporal Genetic Diversity of Feline Calicivirus
... Feline calicivirus (FCV) is an important pathogen of domestic cats and a frequently used model of human ...a calicivirus at re- gional and national ...
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Isolation of Enzymatically Active Replication Complexes from Feline Calicivirus-Infected Cells
... A membranous fraction that could synthesize viral RNA in vitro in the presence of magnesium salt, ribonucleotides, and an ATP-regenerating system was isolated from feline calicivirus (FCV)-infected cells. ...
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Proteinase-Polymerase Precursor as the Active Form of Feline Calicivirus RNA-Dependent RNA Polymerase
... The objective of this study was to identify the active form of the feline calicivirus (FCV) RNA-dependent RNA polymerase (RdRP). Multiple active forms of the FCV RdRP were identified. The most active enzyme ...
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The Feline Calicivirus Leader of the Capsid Protein Is Associated with Cytopathic Effect
... genome. Feline calicivirus (FCV) is in the genus Vesivirus of the family and has been an important model for studying calicivirus replication because it grows efficiently in cell culture and has a ...
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Recovery and Altered Neutralization Specificities of Chimeric Viruses Containing Capsid Protein Domain Exchanges from Antigenically Distinct Strains of Feline Calicivirus
... Feline calicivirus (FCV) strains can show significant antigenic variation when tested for cross-reactivity with antisera produced against other FCV ...
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Identification of Regions and Residues in Feline Junctional Adhesion Molecule Required for Feline Calicivirus Binding and Infection
... The feline junctional adhesion molecule A (fJAM-A) is a functional receptor for feline calicivirus (FCV). fJAM-A is a member of the immunoglobulin superfamily (IgSF) and consists of two Ig-like ...
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Leader of the Capsid Protein in Feline Calicivirus Promotes Replication of Norwalk Virus in Cell Culture
... of feline calicivirus (FCV) was placed under the control of the cytomegalovirus promoter (pCI-LC) so that the LC protein could be provided in trans to replicating calicivirus genomes bearing a ...
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Feline Calicivirus Infection Disrupts Assembly of Cytoplasmic Stress Granules and Induces G3BP1 Cleavage
... The Caliciviridae family contains small RNA viruses of both medical and veterinary importance. Human norovirus (HuNoV) is a leading cause of acute gastroenteritis worldwide, responsible for an estimated 18% of cases and ...
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Mapping of the Feline Calicivirus Proteinase Responsible for Autocatalytic Processing of the Nonstructural Polyprotein and Identification of a Stable Proteinase-Polymerase Precursor Protein
... Feline calicivirus (FCV), a major agent of respiratory illness in cats, is classified in the genus Vesivirus of the family Calici- viridae. The positive-sense single-strand RNA genomes of vi- ruses in the ...
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Cleavage of the Feline Calicivirus Capsid Precursor Is Mediated by a Virus-Encoded Proteinase
... Feline calicivirus (FCV) causes an upper respiratory tract disease in cats and is an important veterinary pathogen (10). Virions are nonenveloped capsids of icosahedral symmetry that carry a VPg-linked ...
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Conserved Surface Residues on the Feline Calicivirus Capsid Are Essential for Interaction with Its Receptor Feline Junctional Adhesion Molecule A (fJAM-A)
... between feline calicivirus (FCV) and its re- ceptor, feline junctional adhesion molecule A (fJAM-A), on host cells is required for infection and induces irreversible, inactivating conformational ...
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Oral Administration Following Subcutaneous Administration of FCV Vaccines Enhances Vaccine Efficacy against Challenge of a Highly Virulent Vs Feline Calicivirus
... include feline calicivirus (FCV), rabbit hemorrhagic disease virus (RHDV), San Miguel sea lion virus (SMSV), vesicular exanthema virus of swine (VEV) and many human caliciviruses [1] ...
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New proof-of-concept in viral inactivation : virucidal efficacy of 405 nm light against feline calicivirus as a model for norovirus decontamination
... Abstract The requirement for novel decontamination technologies for use in hospitals is ever present. One such system uses 405 nm visible light to inactivate microorgan- isms via ROS-generated oxidative damage. Although ...
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Feline Calicivirus Capsid Protein Expression and Capsid Assembly in Cultured Feline Cells
... Calicivirus capsids are structurally simple, with 180 copies of a single structural protein (capsid protein) assembled as 90 homodimers in a T53 icosahedral symmetry (12, 13). The ex- pression of the capsid ...
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Nucleolin Interacts with the Feline Calicivirus 3′ Untranslated Region and the Protease-Polymerase NS6 and NS7 Proteins, Playing a Role in Virus Replication
... and feline calicivirus (FCV) genomic 3 ⴕ untranslated regions ...from feline calicivirus (p76 or NS6/7) from infected feline kidney ...the feline calicivirus NS6/7 ...from ...
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