Ferric carboxymaltose
Intravenous ferric carboxymaltose for anaemia in pregnancy
... Pregnant women with documented IDA, defined as Hb < 115 g/dl, who consecutively presented as outpa- tients in the Women’s Assessment Unit at the Lyell McEwen Hospital (Elizabeth Vale South Australia) to re- ceive ...
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Meta-analysis of efficacy and safety of intravenous ferric carboxymaltose (Ferinject) from clinical trial reports and published trial data
... pared ferric carboxymaltose with blood transfusion, and direct comparisons between different IV iron products were limited in number, but clearly of ...IV ferric carboxymaltose and oral ...
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Ferric carboxymaltose with or without erythropoietin for the prevention of red cell transfusions in the perioperative period of osteoporotic hip fractures: a randomized contolled trial The PAHFRAC 01 project
... i.v. ferric carboxymaltose and erythropoietin (EPOFE arm) versus ...i.v. ferric carboxy- maltose (FE arm) versus placebo (placebo arm) in redu- cing the percentage of patients who receive blood ...
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Efficacy and safety of ferric carboxymaltose versus ferrous sulfate for iron deficiency anemia during pregnancy: subgroup analysis of Korean women
... A sample size of 120 women per treatment arm was considered as sufficiently powered to detect cross-group differences in Hb levels at week 3 versus baseline (α = 0. 05, two-sided; 90% power). The sample size was in- ...
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Effect of ferric carboxymaltose on serum phosphate and C-terminal FGF23 levels in non-dialysis chronic kidney disease patients: post-hoc analysis of a prospective study
... Background: Some parenteral iron therapies have been found to be associated with hypophosphatemia. The mechanism of the decrease in serum phosphate is unknown. The aim of this study is to examine the effect of IV ...
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Effectiveness and safety of ferric carboxymaltose treatment in children and adolescents with inflammatory bowel disease and other gastrointestinal diseases
... sucrose, ferric gluconate, ferric carboxymaltose and ...or ferric carboxymaltose) can be given as large single intravenous ...and ferric carboxymaltose (FCM) appear to ...
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Randomized clinical trial to evaluate ferric carboxymaltose and iron sucrose for treatment of postpartum anaemia in a tertiary hospital
... requirement. Ferric carboxymaltose is a fairly novel iron complex that consists of a ferric hydroxide core stabilized by a carbohydrate shell, allows for controlled delivery of iron to target ...
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AN OBSERVATIONAL STUDY ON SAFETY PROFILE OF FERRIC CARBOXYMALTOSE INTRAVENOUS INFUSION IN IRON DEFICIENCY ANAEMIA PATIENTS IN A TERTIARY CARE HOSPITAL, BANGALORE
... formulations. Ferric carboxymaltose, which overcomes these limitations and it can be used widely as an intravenous iron ...sucrose. Ferric carboxymaltose combines with the positive ...
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Cost-utility of ferric carboxymaltose (Ferinject®) for iron-deficiency anemia patients with chronic heart failure in South Korea
... Methods: Ferric carboxymaltose, an intravenous iron preparation, was compared with ...of ferric carboxymaltose ...and ferric carboxymaltose groups were used to estimate ...
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A study for efficacy and safety of ferric carboxymaltose versus iron sucrose in iron deficiency anemia among pregnant women in tertiary care hospital
... to ferric carboxymaltose raising hemoglobin levels by ...Therefore, ferric carboxymaltose was more efficient and compliant in improving the IDA during the ...(ferric ...
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A comparative study of efficacy and safety of intravenous ferric carboxymaltose versus iron sucrose in the treatment of iron deficiency anaemia of pregnancy in a tertiary care hospital
... The search for an ideal parenteral iron preparation has led to the introduction of Ferric carboxymaltose. This study was conducted with the aim to compare the efficacy and safety of intravenous ...
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FAIRY: a randomized controlled patient blind phase III study to compare the efficacy and safety of intravenous ferric carboxymaltose (Ferinject®) to placebo in patients with acute isovolemic anemia after gastrectomy study protocol for a randomized controlled trial
... Perioperative anemia occurs in 25% to 75% of cancer pa- tients, and the prevalence of anemia in the immediate postoperative period after major surgery is as high as 90% [1,2]. Postoperative acute isovolemic anemia ...
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Single dose of intravenous ferric carboxymaltose infusion versus multiple fractionated doses of intravenous iron sucrose in the treatment of postoperative anaemia in colorectal cancer patients: study protocol for a randomised controlled trial
... of ferric carboxymaltose with fractionated iron sucrose 200 g/48 h for the treatment of postoperative anaemia, by measuring the change of haemoglobin (Hb) levels from postoperative day (POD) 1 to POD ...
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Optimizing iron delivery in the management of anemia: patient considerations and the role of ferric carboxymaltose
... is ferric carboxymaltose (FCM), which has recently been approved by the US Food and Drug Administration for the treatment of iron deficiency anemia in adult patients who are intolerant to oral iron or ...
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Comparison of ferric Carboxymaltose and iron sucrose complex for treatment of iron deficiency anemia in pregnancy randomised controlled trial
... The latest addition in i.v. iron preparations is Ferric Carboxymaltose (FCM), which is a dextran free type I iron complex. A lot of studies have been published on the use of FCM for treatment of anemia in ...
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Renal function in patients with non-dialysis chronic kidney disease receiving intravenous ferric carboxymaltose: an analysis of the randomized FIND-CKD trial
... However, concerns exist about the potential renal toxicity of IV iron therapy [13]. Rapid release of large amounts of iron into the bloodstream could generate ‘free’ iron in the circulation (non-transferrin bound iron, ...
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Evaluation of iron stores in hemodialysis patients on maintenance ferric Carboxymaltose dosing
... sodium ferric gluconate [15] or FCM [16] leads to a transient rise of ferritin, which does not reflect iron stores but rather the iron-induced secretion of ferritin by hepatocytes ...
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Effectiveness and safety of ferric carboxymaltose compared to iron sucrose in women with iron deficiency anemia: phase IV clinical trials
... IDA can be reversed by adequate iron replacement ther- apy, management of the cause of IDA, and maintenance of normal iron levels. The first line therapy: oral therapy, is the intake of 200 mg iron supplement twice or ...
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Assessing the costs and benefits of perioperative iron deficiency anemia management with ferric carboxymaltose in Germany
... Materials and methods: The model was populated with clinical inputs (transfusion rates, blood units transfused, hospital length of stay) from a previously reported randomized trial com[r] ...
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Cardiovascular, liver, and renal toxicity associated with an intravenous ferric carboxymaltose similar versus the originator compound
... TNF α levels were increased in the FCMS group versus the FCM and control groups in liver, heart, and kidney tissue (all P , 0.01; Figure 4A).. A significant difference between the FC[r] ...
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