Fibronectin and cancer
Original Article Upregulation of fibronectin, vitronectin and claudin-7 in cervical cancer
... including fibronectin, vitronectin and claudin-7 in cervival cancer ...for fibronectin, ...that fibronectin, vitronectin and claudin-7 were all significantly upregulated in cervival ...
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Fibronectin on circulating extracellular vesicles as a liquid biopsy to detect breast cancer
... and fibronectin immunoreactivity in breast ...J. Fibronectin stimulates non- small cell lung carcinoma cell growth through activation of Akt/mammalian target of rapamycin/S6 kinase and inactivation of ...
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Fibronectin acts as a molecular switch to determine SPARC function in pancreatic cancer.
... pancreatic cancer cell ...important cancer growth factor TGF-β also remained unchanged in SPARC-siRNA transfected PS-1 cells over 3 days (Figure ...in fibronectin secretion was observed, as ...
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Mesothelial cells promote early ovarian cancer metastasis through fibronectin secretion
... the fibronectin secreted by mesothelial cells is important for the metastatic process of OvCa cells, should have considerable relevance when selecting clini- cally useful targeted ...short fibronectin ...
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Therapeutic vaccination against fibronectin ED-A attenuates progression of metastatic breast cancer
... for cancer and various inflammatory diseases. However, development of cancer vaccines targeting self-molecules has proven ...of fibronectin are expressed during vasculogenesis in the embryo, but ...
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Tumor cell-organized fibronectin is required to maintain a dormant breast cancer population [preprint]
... with cancer cells entering a largely quiescent, non- proliferative state before reactivation and ...fibrillar fibronectin matrix via a v b 3 and a 5 b 1 integrin adhesion, ROCK-generated tension, and TGFβ2 ...
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Fibronectin 1 promotes migration and invasion of papillary thyroid cancer and predicts papillary thyroid cancer lymph node metastasis
... in cancer invasion and metastasis in a sequence of discrete ...and fibronectin, are the most important features of ...colorectal cancer patients at risk for metastatic disease independently of LN ...
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Down-regulation of ARNT promotes cancer metastasis by activating the fibronectin/integrin β1/FAK axis
... colorectal cancer using immunohistochemical ...promoted cancer cell migration and invasion, which was mediated by activation of the fibronectin/integrin β1/FAK signaling ...
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Effectiveness of urine fibronectin as a non invasive diagnostic biomarker in bladder cancer patients: a systematic review and meta analysis
... Conclusions In conclusion, by evaluating the pooled sensitivity, specifi- city, PLR, NLR, DOR, and AUC from 11 studies, the present meta-analysis revealed that measurement of urine fibronectin appears to be ...
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Expression Analysis of Fibronectin Type III Domain-Containing (FNDC) Genes in Inflammatory Bowel Disease and Colorectal Cancer
... Received 27 November 2018; Revised 21 January 2019; Accepted 5 February 2019; Published 9 April 2019 Academic Editor: Jean-Francois Beaulieu Copyright © 2019 Tilo Wuensch et al. This is an open access article distributed ...
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<p>miR-1-3p suppresses the epithelial-mesenchymal transition property in renal cell cancer by downregulating Fibronectin 1</p>
... of Fibronectin 1 in RCC cells. Fibronectin 1 is a matrix glycoprotein that increased in several carcinoma cell types, including ...years, Fibronectin 1 has been gradually certi fi ed as an oncogene, ...
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Fibronectin-1 expression is increased in aggressive thyroid cancer and favors the migration and invasion of cancer cells
... thyroid cancer based on analysis of tumor tissue specimens or fine needle aspiration biopsies (FNAB) ( Frykn€as et ...thyroid cancer has never been ...
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Fibronectin rescues estrogen receptor α from lysosomal degradation in breast cancer cells
... Discussion In this study, we demonstrate by biochemical approaches and high-resolution microscopy that E 2 induces endocytosis of ERα by a mechanism involving caveolin 1. In the presence of FN, ERα avoids lysosomal ...
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CIP2A mediates fibronectin-induced bladder cancer cell proliferation by stabilizing β-catenin
... bladder cancer [26], which coinciding with our IHC analysis ...forces cancer progression though complex signaling ...bladder cancer cell biological behaviors have been little ...gallbladder ...
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Trop-2 inhibits prostate cancer cell adhesion to fibronectin through the β1 integrin-RACK1 axis.
... including cancer metastasis. Moreover, regulation of the physical link between integrins and the actin cytoskeleton is critical for the spatio-temporal control of cell detachment from the substrate, cell migration ...
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The initial steps of ovarian cancer cell metastasis are mediated by MMP 2 cleavage of vitronectin and fibronectin
... proteins fibronectin (FN) and vitronectin (Vn) into small fragments and increased binding of OvCa cells to these FN and Vn fragments and their receptors, a 5 b 1 and a V b 3 ...
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Mechanostimulation of integrin αvβ6 and fibronectin in DCISmyoepithelial cells
... Notably, intermediate-grade DCIS exhibited a hybrid of these signatures [66]. These data support the different pathological grades of DCIS progress to IDC by two distinct pathways. In the low-grade arm, tumours are of ...
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tenascin‑C, fibronectin and galectin‑3 in prostatic adenocarcinoma
... ABSTRACT Introduction: The interchanged stromal-epithelial relations and altered expression profiles of various extracellular matrix (ECM) proteins creates a suitable microenvironment for cancer development and ...
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Allosteric Regulation of Fibronectin/α5β1 Interaction by Fibronectin-Binding MSCRAMMs
... Abstract Adherence of microbes to host tissues is a hallmark of infectious disease and is often mediated by a class of adhesins termed MSCRAMMs (Microbial Surface Components Recognizing Adhesive Matrix Molecules). ...
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Allosteric Regulation of Fibronectin/α5β1 Interaction by Fibronectin-Binding MSCRAMMs
... * [email protected] Abstract Adherence of microbes to host tissues is a hallmark of infectious disease and is often medi- ated by a class of adhesins termed MSCRAMMs (Microbial Surface Components Recogniz- ing ...
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