Fluconazole resistance
Fluconazole resistance in <em>Candida</em> species: a current perspective
... to fluconazole carried point mutations which had been previously shown to impact drug resistance in other Candida ...the fluconazole- resistant phenotype of these ...
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Emergence of Fluconazole Resistance in a Candida parapsilosis Strain That Caused Infections in a Neonatal Intensive Care Unit
... of fluconazole resistance and the increase in the proportions of intrinsically fluconazole-resistant Candida isolates are of concern when prophylaxis is ...azole resistance or reduced ...
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Clonal and Spontaneous Origins of Fluconazole Resistance in Candida albicans
... to fluconazole of 78 strains of the human pathogenic yeast Candida albicans were ...of fluconazole was determined by the standard National Committee for Clinical Laboratory Standards ...of ...
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Jjj1 Is a Negative Regulator of Pdr1-Mediated Fluconazole Resistance in Candida glabrata
... fluconazole resistance among clinical isolates of Candida glabrata has greatly hampered the utility of fluconazole for the treatment of invasive ...candidiasis. Fluconazole resistance in this yeast is ...
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MDR1 overexpression combined with ERG11 mutations induce high level fluconazole resistance in Candida tropicalis clinical isolates
... that fluconazole-resistant isolates had significantly higher expression levels of the MDR1 gene than control ...high-level fluconazole- resistant isolates had higher levels of MDR1 expression than low-level ...
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Overexpression of MDR-1 and CDR-2 genes in fluconazole resistance of Candida albicans isolated from patients with vulvovaginal candidiasis
... of fluconazole- resistant ...(RVVC). Fluconazole resistance can occur through different mechanisms involving mutations in the drug target enzyme and sterol 14a-demethylase (14DM), alterations in ...
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Hospital Specificity, Region Specificity, and Fluconazole Resistance of Candida albicans Bloodstream Isolates
... among fluconazole-resistant BSI isolates in the collection, either from the same geographic locale or the same ...drug resistance of Candida isolates responsible for ...
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Development of fluconazole resistance in a series of Candida parapsilosis isolates from a persistent candidemia patient with prolonged antifungal therapy
... received fluconazole treatment for more than 3 ...when fluconazole treatment was commenced it was initially at a lower dose because of chronic renal failure, and on the basis of sputum micros- ...suboptimal ...
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Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis
... These results have clinical and microbiologic implications. In agreement with prior in vitro studies (24), most strains were het- eroresistant at baseline, prior to the administration of any FLC treatment, in a ...
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Dynamic ploidy changes drive fluconazole resistance in human cryptococcal meningitis
... These results have clinical and microbiologic implications. In agreement with prior in vitro studies (24), most strains were het- eroresistant at baseline, prior to the administration of any FLC treatment, in a ...
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Adaptive Mistranslation Accelerates the Evolution of Fluconazole Resistance and Induces Major Genomic and Gene Expression Alterations in Candida albicans
... drug resistance in bacteria (17, 31), but its role in eukaryotes is still poorly ...acquire resistance to ...the resistance to fluconazole of both the WT T0 and hypermistranslating T1 strains was ...
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Susceptibility pattern of anti-candida drugs in the pediatric patients with acute leukemia
... include fluconazole, voriconazole, itraconazole, ketoconazole, and ...posaconazole. Resistance to azoles was found in all Candida ...confer resistance to multiple azoles and have been associated with ...
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A Study on Speciation and Antifungal Susceptibility Pattern of Candida Isolates from HIV Patients with Oropharyngeal Candidiasis and Correlation with Cd4 Count.
... to Fluconazole and 23 ...were fluconazole resistant. CA Enwuru et al 2008 showed that fluconazole resistance was observed in ...to fluconazole and itraconazole ...were ...
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Extensive ERG11 mutations associated with fluconazole-resistant Candida albicans isolated from HIV-infected patients
... drug resistance genes (i.e., CDR1 and CDR2), and multiple drug resistance genes ...antifungal resistance. Sequestration of fluconazole within intracellular vacuoles can be another novel ...
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A study on biofilm production and antifungal drug resistance among Candida species from vulvovaginal and bloodstream infections
... with resistance to both fluconazole and voriconazole; only one out of 102 isolates showed fluconazole resistance, and among blood samples, 13 of 74 ...with resistance to ...
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Variations in fluconazole susceptibility and electrophoretic karyotype among oral isolates of Candida albicans from patients with AIDS and oral candidiasis
... DNA subtyping by pulsed-field gel electrophoresis and in vitro susceptibility testing were used to study strain variation and fluconazole resistance in Candida albicans isolates from pat[r] ...
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Replacement of Candida albicans with C dubliniensis in Human Immunodeficiency Virus Infected Patients with Oropharyngeal Candidiasis Treated with Fluconazole
... to fluconazole, the inducibility of azole resistance in vitro has been ...of fluconazole prophylaxis in the treatment of these patients may have contributed to the increasing rates of isolation of ...
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The trend of susceptibilities to amphotericin B and fluconazole of Candida species from 1999 to 2002 in Taiwan
... Antimicrobial Resistance of Yeasts (TSARY) was initiated in 1999 for epi- demiological study of yeast infections in Taiwan [8,9] Candida species have various degrees of susceptibility to common antifungal ...to ...
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An update on the application of nano-scaled carriers against fluconazole-resistant Candida species: nanostructured lipid carriers or solid lipid nanoparticles?
... azole resistance in fungi which reduces the intracellular azole concentrations below the levels at which Erg11p is inhibited ...of fluconazole resistance in multiple Candida species ...of ...
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Multidrug Resistant Candida auris Misidentified as Candida haemulonii: Characterization by Matrix Assisted Laser Desorption Ionization–Time of Flight Mass Spectrometry and DNA Sequencing and Its Antifungal Susceptibility Profile Variability by Vitek 2, CLSI Broth Microdilution, and Etest Method
... care general hospitals and a pediatric center in north and south India, representing 8.6% to 30% of cases of candidemia (7, 8). The actual prevalence of C. auris in varied clinical settings in India is unexplored, as the ...
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