Fluorescence-guided surgery
Targeting CD44v6 for fluorescence-guided surgery in head and neck squamous cell carcinoma
... during surgery. Fluorescence-guided surgery (FGS), by intraoperative detection of tumor cells using a fluorescent tracer, may guide surgical excision and identify tumor-positive resection ...
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Targeting tumors with a killer-reporter adenovirus for curative fluorescence-guided surgery of soft-tissue sarcoma
... The tumor-bearing mice were injected with high and low-dose telomerase-dependent, green fluorescent protein (GFP)-containing adenovirus OBP-401, which labeled the tumor with GFP. Fluorescence-guided ...
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Adenoviral targeting of malignant melanoma for fluorescence- guided surgery prevents recurrence in orthotopic nude-mouse models
... OBP-401-based fluorescence-guided surgery (FGS) resulted in the complete resection of malignant melanoma in the orthotopic models, where conventional bright-light surgery (BLS) could ...
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Tracers for Fluorescence-Guided Surgery: How Elongation of the Polymethine Chain in Cyanine Dyes Alters the Pharmacokinetics of a Dual-Modality c[RGDyK] Tracer
... example, common confocal microscopes can be considered a lim- iting factor during the in vitro stages of tracer evaluation. Combined, the reported findings advocate careful selection of dye during the development of ...
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Perspective Review of what is Needed for Molecular-Specific Fluorescence-Guided Surgery
... section fluorescence imaging to fixed H&E pathology images, which requires chal- lenging and labor-intensive comparison ...vivo fluorescence with ex vivo tumor delineation might be a solution in this ...
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EpCAM as multi-tumour target for near-infrared fluorescence guided surgery
... intra-operative fluorescence imaging using the EpCAM specific antibody 323/A3- 800CW in combination with 2 imaging ...and fluorescence imaging using the Pearl and Artemis imaging system was ...removed. ...
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Fluorescence-Guided Surgery for High- Grade Gliomas: State of the Art and New Perspectives
... induced fluorescence in oncological setting and non- oncological ...positive fluorescence reported in literature in the oncological ...positive fluorescence dur- ing first surgery for ...
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A Tumor-Activatable Theranostic Nanomedicine Platform for NIR Fluorescence-Guided Surgery and Combinatorial Phototherapy
... cytoreductive surgery [5, ...[9]. Fluorescence image-guided surgery has a great potential for intraoperative detection of oncologic targets and real-time assessment of tumor borders, thus ...
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A phase II trial of autologous dendritic cell vaccination and radiochemotherapy following fluorescence guided surgery in newly diagnosed glioblastoma patients
... Therefore, the only favorable factor embedded in our inclusion criteria was that we performed an extensive resection in all cases. In other words, we included only patients with potentially resectable tumors, which is a ...
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Characterization and Evaluation of the Artemis Camera for Fluorescence-Guided Cancer Surgery
... NIR fluorescence-guided surgery could aid surgeons in real-time visualization of tumors, SLNs, and vital structures to ensure a radical resection, adequate staging, and minimize damage to normal ...
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PSMA-targeting agents for radio- and fluorescence-guided prostate cancer surgery
... YC-27 fluorescence-guidance developed a recurrence, whereas 40% of the mice with conventional white light resection developed recurrence within 30 days after resection ...in fluorescence-guided ...
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Liver segment imaging using monocyte sequestration: a potential tool for fluorescence-guided liver surgery
... selected segment using IRDye 800CW-labeled monocytes. Although non-conjugated IRDye 800CW and ICG have comparable molar extinction coefficients [32, 33], IRDye800CW-conjugated antibodies and proteins have substantially ...
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A narrative review of fluorescence imaging in robotic-assisted surgery
... of fluorescence imaging in urologic, gynecologic, general, and endocrine ...robotic-assisted surgery has helped increase the availability of minimally invasive procedures across surgical specialties, there ...
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Fluorescence guided visualization of soft tissue sarcomas by targeting vascular endothelial
... specific fluorescence activation in areas containing soft tissue tumor as assessed by H/E staining confirm these preclinical results and are in accordance with earlier clinical reported ...primary surgery ...
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Fluorescence-guided cancer surgery : clinical translation of tumor-targeted agents
... nir fluorescence imaging in staging procedures, the detection of occult metastases, could not be demonstrated in this study as metastatic lesions were not present in any of the ...
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A practical guide for the use of indocyanine green and methylene blue in fluorescence-guided abdominal surgery
... colorectal surgery, using ICG due to its ...abdominal surgery, would be limited subject due to higher absorption and more nonspecific background ...abdominal surgery for detection of neuroendocrine ...
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<p>NIR fluorescence-guided tumor surgery: new strategies for the use of indocyanine green</p>
... Organic ICG nanoparticles The characteristics (nature, size) of the nanoparticles described in this section and the tumor models used are presented in Table 2. Poly(lactic-co-glycolic acid) (PLGA) carriers are one of the ...
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Surgery guided by 5-aminolevulinic fluorescence in glioblastoma: volumetric analysis of extent of resection in singlecenter experience
... of surgery guided by 5-aminolevulinic acid (ALA) fluorescence in consecutive patients with glioblastoma multiforme ...Strong fluorescence identified solid tumor with 100% positive predictive ...
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Pretargeted Dual-Modality Immuno-SPECT and Near-Infrared Fluorescence Imaging for Image-Guided Surgery of Prostate Cancer
... image- guided surgery using intraoperative NIRF imaging, showing the preclinical feasibility of pretargeted dual- modality imaging approach in prostate ...
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CURVETM Image Guided Surgery
... Dual-option, beyond HD, 26-inch touch monitors with 16:10 screen ratio provide more space to display and efficiently organize information; surgeons are guided by images from multi[r] ...
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