Fluticasone furoate
Patient considerations in the treatment of COPD: focus on the new combination inhaler fluticasone furoate/umeclidinium/vilanterol
... Abstract: The pharmacological treatment for stable COPD is based on the use of inhaled bronchodilators (long-acting muscarinic receptor antagonists and long-acting beta-2 adreno- ceptor agonists) and inhaled ...
9
Human receptor kinetics and lung tissue retention of the enhanced-affinity glucocorticoid fluticasone furoate
... Fluticasone furoate (FF) – USAN approved name, a new topically active glucocorticoid has been recently ...of fluticasone furoate to human lung ...of fluticasone furoate revealed ...
9
Fluticasone furoate nasal spray: Profile of an enhanced-affinity corticosteroid in treatment of seasonal allergic rhinitis
... corticosteroid fluticasone furoate nasal spray (GW685698X), is one of the newest additions to the armamentarium for allergic ...on fluticasone furoate nasal spray and discusses its place in ...
13
Fluticasone furoate: once-daily evening treatment versus twice-daily treatment in moderate asthma
... ICS fluticasone furoate (FF) has a long dura- tion of action and prolonged retention in the lung, sug- gesting that it is suitable for once-daily dosing ...and fluticasone propionate (FP) are ...
8
Single-inhaler triple therapy fluticasone furoate/umeclidinium/vilanterol versus fluticasone furoate/vilanterol and umeclidinium/vilanterol in patients with COPD: results on cardiovascular safety from the IMPACT trial
... Background: This analysis of the IMPACT study assessed the cardiovascular (CV) safety of single-inhaler triple therapy with fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/VI) versus FF/VI and UMEC/VI ...
12
Single-inhaler fluticasone furoate/umeclidinium/vilanterol versus fluticasone furoate/vilanterol plus umeclidinium using two inhalers for chronic obstructive pulmonary disease: a randomized non-inferiority study
... severe exacerbation rate, with once-daily, single-inhaler fluticasone furoate/umeclidinium/vilanterol (FF/UMEC/ VI) versus twice-daily budesonide/formoterol (FOR) [10]. Similarly, the TRILOGY study showed ...
10
Profile of fluticasone furoate/vilanterol dry powder inhaler combination therapy as a potential treatment for COPD
... Once-daily fluticasone furoate/vilanterol dry powder inhaler combination therapy has recently been approved by the US Food and Drug Administration and the European Medicines Agency as a new regular ...
8
Spotlight on fluticasone furoate/umeclidinium/vilanterol in COPD: design, development, and potential place in therapy
... Umeclidinium/fluticasone furoate/vilanterol is one such triple-combination therapy currently under development with some completed and several ongoing clinical ...umeclidinium, fluticasone ...
6
Fluticasone furoate/Vilanterol 92/22 μg once-a-day vs Beclomethasone dipropionate/ Formoterol 100/6 μg b.i.d.: a 12-week cost analysis in mild-to-moderate asthma
... once-a-day. The hospitalization cost, which is the main component of cost, dropped by 50 % with Fluticasone furoate/Vilanterol 92/22 μg once-a-day. Unfortunately, due to both a certain dispersion of data ...
7
Efficacy in asthma of once-daily treatment with fluticasone furoate: a randomized, placebo-controlled trial
... Fluticasone furoate (FF) is a novel ICS and is structurally different to fluticasone propionate (FP). FF has an ester derived from 2-furoic acid at the C-17a position that replaces the simpler ...
11
Cost–consequence analysis of fluticasone furoate/vilanterol 92/22 mcg for the management of COPD in the Spanish NHS
... once-daily fluticasone furoate/vilanterol (FF/VI) 92/22 mcg with continuing usual care (UC) in patients with COPD followed in primary care in the ...
10
Original Article Efficacy and safety of vilanterol and fluticasone furoate/vilanterol in the treatment of asthma: a systematic review and meta-analysis
... fluticasone furoate/vilanter- ol in the treatment of ...fluticasone furoate/vilanterol (FF/VI) significantly improved trough FEV1 (140 ml, ...placebo. Fluticasone furoate/vilanterol treatment ...
14
Anti-inflammatory duration of action of fluticasone furoate/vilanterol trifenatate in asthma: a cross-over randomised controlled trial
... Fluticasone furoate / Vilanterol trifenatate (FF/VI) 100/25 mcg is an ICS/LABA combination licensed for the once-daily treatment of asthma and chronic obstructive pulmonary disease ...
11
A randomized trial of once-daily fluticasone furoate/vilanterol or vilanterol versus placebo to determine effects on arterial stiffness in COPD
... Materials and methods: The effects of once-daily inhaled fluticasone furoate/vilanterol (FF/VI) 100/25 µg, VI 25 µg, versus placebo on arterial stiffness in patients with COPD and baseline aPWV $11.0 m/s ...
15
Once-daily fluticasone furoate/vilanterol versus twice daily combination therapies in asthma–mixed treatment comparisons of clinical efficacy
... of fluticasone furoate/vilanterol compared with fluticasone propionate/salmeterol combination in adult and adolescent patients with persistent asthma: a randomized ...
12
<p>Once-daily fluticasone furoate/vilanterol combination versus twice-daily budesonide/formoterol combination in the treatment of controlled stable asthma: a randomized crossover trial</p>
... Fluticasone furoate/Vilanterol is an ICS/LABA combi- nation therapy with inherent 24 hrs activity, currently used as a once-daily treatment ...device. Fluticasone furoate has been shown to ...
9
Fluticasone furoate/Vilanterol 92/22 μg once-a-day vs Beclomethasone dipropionate/Formoterol 100/6 μg b.I.D.: a 12-month comparison of outcomes in mild-to-moderate asthma
... combined Fluticasone furoate/Vilanterol 92/22 μg once-daily for twelve months consents an enhanced and time-dependent efficacy in terms of lung function and of all main clinical outcomes when compared to ...
11
Integrated safety and efficacy analysis of once-daily fluticasone furoate for the treatment of asthma
... ICS fluticasone furoate (FF), administered using the ELLIPTA® dry powder inhaler, is a once-daily main- tenance treatment for adult and adolescent (≥12 years) patients with ...
11
A randomized study comparing the efficacy of mometasone furoate and fluticasone furoate on the ocular and nasal symptoms of allergic rhinitis
... mometasone furoate nasal spray at a dose of 200 µg per day once daily and Group B received treatment with fluticasone furoate nasal spray at a dose of 110 µg once daily for 3 ...
5
Vilanterol and fluticasone furoate for chronic asthma in adults and children
... and a leukotriene antagonist (LTRA) is a valid alternative to ICS combined with LABA (Montuschi 2008; Montuschi 2010). Inhaled corticosteroids are fundamental in the treatment of asthma, and fluticasone ...
143