focal cortical dysplasia
Abnormal Blood Oxygen Level–Dependent Fluctuations in Focal Cortical Dysplasia and the Perilesional Zone: Initial Findings
... of focal cortical dysplasia ...of focal cortical dysplasia lesions and comparing current results with electrophysiologic ...
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Focal cortical dysplasia of Taylor, balloon cell subtype: MR differentiation from low grade tumors
... of focal gyral thickening, abnormal demarcation of the gray–white matter junction, and/or increased signal on long-TR ...III focal cortical dysplasia). MR imaging showed focal ...
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MRI, Magnetoencephalography, and Surgical Outcome of Oligodendrocytosis versus Focal Cortical Dysplasia Type I
... had focal cortical dysplasia I, and 7 ...⫹ focal cortical dysplasia ...seizures, focal or nonfocal epileptiform discharges, magnetoencephalog- raphy, and MR imaging ...
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Altered expression of neuropeptide Y receptors caused by focal cortical dysplasia in human intractable epilepsy
... Focal cortical dysplasia (FCD) is a common cause of pharmacologically-intractable epilepsy, however, the precise mechanisms underlying the epileptogenicity of FCD remains to be ...
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Clinical Features of a Series of Non-Surgical Patients with Focal Cortical Dysplasia and Epilepsy
... with focal cortical dysplasia and epilepsy are surgical or pathological series of pediatric ...of focal cortical dysplasia by standardized ...drugs. Focal seizures were ...
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Downregulation of CD47 and CD200 in patients with focal cortical dysplasia type IIb and tuberous sclerosis complex
... of cortical development (MCD) are major causes of intractable pediatric epilepsy ...[1]. Focal cortical dysplasia (FCD) and tuberous sclerosis complex (TSC) are two common classes of MCD ...
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Case Report Encephalomalacic dysplastic mass lesion associated with vascular abnormalities in an elderly man. Is this “acquired” focal cortical dysplasia?
... Abstract: Focal cortical dysplasia (FCD) is known to occur in association with a principal lesion and has been newly introduced as FCD type III in the ILAE 2011 classification system of ...laminar ...
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Clinical and immunohistochemical characteristics of type II and type I focal cortical dysplasia
... Focal cortical dysplasia (FCD) II and I are major causes for drug-resistant epilepsy. In order to gain insight into the possible correlations between FCD II and FCD I, different clinical ...
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Second hit mosaic mutation in mTORC1 repressor DEPDC5 causes focal cortical dysplasia–associated epilepsy
... refractory focal epilepsies, with case reports of sudden unexpected death in epilepsy ...develop focal cortical dysplasia (FCD), a neurodevelopmental cortical ...the focal nature ...
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Identification and immunophenotype of abnormal cells present in focal cortical dysplasia type IIb
... Focal cortical dysplasia was first defined by (Taylor et ...normal cortical lamination with large bizarre neurons and ...of cortical lamination, and type Ib additionally presented ...
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Radiologic and Pathologic Features of the Transmantle Sign in Focal Cortical Dysplasia: The T1 Signal Is Useful for Differentiating Subtypes
... of focal malfor- mations due to abnormal cortical development: direct electrocortico- graphic-histopathologic ...2 focal cortical dysplasia: best criteria for clinical ...Taylor-type ...
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Upregulation of HMGB1-TLR4 inflammatory pathway in focal cortical dysplasia type II
... (2) focal cortical dysplasia was suggested in brain magnetic resonance imaging (MRI): focal changes in the cortical thickness, signal increase (mainly on T2FLAIR and T2WI sequences), ...
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Optimizing MR Imaging Detection of Type 2 Focal Cortical Dysplasia: Best Criteria for Clinical Practice
... MATERIALS AND METHODS: We retrospectively reviewed 1.5T MR imaging of 71 consecutive patients with histologically proved type 2 FCD. The protocol included millimetric 3D T1-weighted, 2D coronal and axial T2-weighted, and ...
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Germline and somatic mutations in the MTOR gene in focal cortical dysplasia and epilepsy
... series of patients with FCD, we could not directly correlate the allele frequencies of somatic variants to the size of the lesion. Given the central and ubiqui- tous role of the mTORC1 transduction pathway in regulating ...
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Disorganization of neocortical lamination in focal cortical dysplasia is brain-region dependent: evidence from layer-specific marker expression
... A detailed characterization of architectural distur- bances has recently become possible by using layer- specific markers which specifically label subsets of cortical neuron types with restricted laminar ...
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Layer-specific gene expression in epileptogenic type II focal cortical dysplasia: normal-looking neurons reveal the presence of a hidden laminar organization
... glutamatergic) cortical neurons with very high laminar specificity, and can thus be used as markers to identify different cor- tical ...investigate cortical development under normal ...
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<p>Histological type of focal cortical dysplasia is associated with the risk of postsurgical seizure in children and adolescents</p>
... Based on the results of the presurgical evaluation, deci- sions regarding the type and extent of surgery were made for each individual patient after a multidisciplinary case discussion. The resection areas included the ...
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Ultra High Field Targeted Imaging of Focal Cortical Dysplasia: The Intracortical Black Line Sign in Type IIb
... Ultra-high-field MR imaging offers an enhanced spatial reso- lution reaching microscopic values due to its high signal-to-noise ratio, allowing the different components within the cortex to be visualized, especially ...
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MRI Abnormalities Predominate in the Bottom Part of the Sulcus with Type II Focal Cortical Dysplasia: A Quantitative Study
... We explored the spatial distribution of abnormal findings on MR imaging across the sulci containing FCD II lesions using quanti- tative techniques. Our results suggest that gray-white matter junc- tion blurring and ...
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Longitudinal Findings of MRI and PET in West Syndrome with Subtle Focal Cortical Dysplasia
... the MR imaging lesion (Fig 1D, -E). The EEG at 24 months of age showed repetitive focal spikes, polyspikes, and slow waves in the left frontal area, concordant with the MR imaging lesion. The paroxysmal epileptic ...
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