folate deficiency
Folate deficiency as predisposing factor for childhood leukaemia: a review of the literature
... between folate intake and the risk of childhood ...life. Folate deficiency is capable of modifying the methylation status of certain genes at birth in both animals and humans, with potential ...
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Up-regulation of RNA Binding Proteins Contributes to Folate Deficiency-Induced Neural Crest Cells Dysfunction
... as folate deficiency, has long been associated with neurocristopathies and NTDs ...in folate in the periconceptional period and the role of folic acid (FA) in preventing neurocristopathies [21] and ...
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Screening for vitamin B 12 and folate deficiency in older persons
... and folate are involved in a common metabolic pathway supplying essential methyl groups for DNA and protein syn- thesis ...donor. Deficiency of either folate or vitamin B-12 results in increased ...
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Follow-up of folinic acid supplementation for patients with cerebral folate deficiency and Kearns-Sayre syndrome
... Design: open label study. We recruited eight patients with diagnoses of mtDNA single large-scale deletion syndrome and cerebral folate deficiency. Case 1 had Pearson’s syndrome at onset but evolved to a ...
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Folate Deficiency and Its Impact on NTDs Prevalence in Georgia
... Folate deficiency in the periconceptional period contributes to neural tube defects; deficits in vitamin B12 (cobalamin) have negative consequences on the developing brain during infancy; and deficits of ...
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Folate deficiency induced H2A ubiquitination to lead to downregulated expression of genes involved in neural tube defects
... that folate deficiency affected DNA break- age through histone H3K4me1, leading to regulation of transcription of rRNA genes during the early stage of development and offering new insights into the etiol- ...
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Folate-deficiency induced cell-specific changes in the distribution of lymphocytes and granulocytes in rats
... The extensive reduction in the number of circulating B-lymphocytes due to folate deficiency may cause anti- body production against pathogenic microoganisms to be depressed. Further study is necessary to ...
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Experimental folate deficiency in human subjects: what is the influence of vitamin C status on time taken to develop megaloblastic anaemia?
... on poor diets almost devoid of vegetables, with interven- tions including vitamin C, improved diet and bed rest. Based on his own experimental results, and other published studies in which the anaemia was successfully ...
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Low fruit consumption and folate deficiency are associated with LINE-1 hypomethylation in women of a cancer-free population
... There are growing interests in determining how dietary patterns and specific micronutrients and macronutrients may affect global DNA methylation levels. In our study, we hypothesized that a low adherence to MD and ...
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Elevation of total homocysteine in the serum of patients with cobalamin or folate deficiency detected by capillary gas chromatography mass spectrometry
... or folate deficiency, we utilized a new capillary gas chromatographic-mass spectrometric technique to measure total homocysteine in the serum of 78 patients with clinically confirmed cobalamin ...
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Folate deficiency-triggered redox pathways confer drug resistance in hepatocellular carcinoma
... with folate (2 μmole/L), thymidine (36 μmole/L), hypoxanthine (36 μmole/L), glycine (600 μmole/L), serine (250 ...formulate folate-deficient media, folate as well as thymidine, hypoxanthine and ...
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SERUM FOLATE DEFICIENCY IN CHILDREN RECEIVING ANTICONVULSANT THERAPY
... Hematologic studies including assays of serum folic acid were performed in 37 epileptic children receiving various anticonvulsant regimens and 20 healthy children.. Values for hemoglobin[r] ...
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Mild folate deficiency induces genetic and epigenetic instability and phenotype changes in prostate cancer cells
... mild folate depletion in a model comprised of three syngenic cell lines derived from the transgenic adenoma of the mouse prostate (TRAMP) model, recapitulating different stages of prostate cancer; benign, ...
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FOLIC ACID BIOAVAILABILITY: A REVIEW
... Folate deficiency is often associated with the increased nutritional requirement of folate or due to a lack of folate-rich ...affect folate availability resulting in its ...
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Translational upregulation of folate receptors is mediated by homocysteine via RNA heterogeneous nuclear ribonucleoprotein E1 interactions
... of folate deficien- cy indicated that the only metabolite of physiological relevance and that increased with time was homocys- teine (Figure ...in folate-replete cells was higher than total homocysteine ...
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Readmission and mortality one year after acute hospitalization in older patients with explained and unexplained anemia - a prospective observational cohort study
... Background: Few studies have examined whether specific subtypes of anemia in older persons are more related to adverse outcomes such as hospital readmissions and death after acute hospitalization and post-acute care. ...
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World Journal of Nutrition and Health
... to folate deficiency. Folate and vitamin B12 deficiencies are the most common causes of macrocytic megaloblastic anemia ...[7,8]. Folate deficiency during the first weeks of pregnancy ...
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Folate status in type 2 diabetic patients with and without retinopathy<div><br /></div>
... Red folate blood is inversely related to HbA 1c . Analysis of folate in red cells is considered to be a strong indicator of folate adequacy because it reflects intracellular status and is not ...
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Change in platelet endothelial cell adhesion molecule-1 immunoreactivity in the dentate gyrus in gerbils fed a folate-deficient diet
... group. Folate is a cofactor in 1-carbon metabolism, during which it promotes the remethylation of ...of folate has a major impact on homosysteine levels, with an inverse relationship between plasma ...
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Fermentation of Milk Using Folate-Producing Lactic Acid Bacteria to Increase Natural Folate Content: A Review
... Natural folate is available in food but it is very unstable. Synthetic folate is generally used as an alternative to meet daily needs due to its stability, even though it has a negative effect causing a ...
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