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forced swimming

Effect of rhizome extract of Acorus calamus on depressive condition induced by forced swimming in mice

Effect of rhizome extract of Acorus calamus on depressive condition induced by forced swimming in mice

... In the present study, we have evaluated the antidepressant activity of methanol extract of A.calamus rhizome (MEA) in mice by forced swimming test. It is a behavioral test for screening the drugs or the ...

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Effects of Laminaria japonica polysaccharides on exercise endurance and oxidative stress in forced swimming mouse model

Effects of Laminaria japonica polysaccharides on exercise endurance and oxidative stress in forced swimming mouse model

... After the final LJP or vehicle treatment, the mice were allowed to rest for 30 min, and then they were subjected to the forced swimming test using the method described by Li et al. [11]. The apparatus used ...

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Antistress Effect of Fagopyrum esculentum in Rats subjected to Forced Swimming Endurance Test

Antistress Effect of Fagopyrum esculentum in Rats subjected to Forced Swimming Endurance Test

... The forced swimming is the most widely used method for assessing the antistress property of novel ...animals forced to swim in water eventually assumed a characteristic immobile posture, devoid of ...

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The effect of montelukast on depression behavior in rat forced swimming test

The effect of montelukast on depression behavior in rat forced swimming test

... Method: 50 wistar albino female rats, of between 150 and 250 g in weight, were used in this study. The study was conducted with two groups: Group I: healthy group; including control, asthma, and montelukast-treated ...

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Evaluation of Antifatigue Effects of 20(S)-Ginsenoside Rg3 in Forced Swimming Mice

Evaluation of Antifatigue Effects of 20(S)-Ginsenoside Rg3 in Forced Swimming Mice

... The main objective of this study was to investigate the antifatigue effects of 20(S)-ginsenoside Rg3 using forced swimming test in mice. Male Kunming mice were randomly divided into four groups; a control ...

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Antioxidant Properties of Aqueous Extract of Salvadora persica in Rats Subjected to Forced Swimming Test

Antioxidant Properties of Aqueous Extract of Salvadora persica in Rats Subjected to Forced Swimming Test

... The forced swimming test represents a valid animal model for screening ant fatigue potency of various bioactive compounds [34]. According to results of HPLC and the literature, the antidepressants like ...

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Effect of Achyranthes Aspera Linn on Modified Forced Swimming In Rats

Effect of Achyranthes Aspera Linn on Modified Forced Swimming In Rats

... The forced swimming test (FST), described originally [2] is widely used as an animal model to assess the antidepressant action ...increases swimming behavior ...increase swimming [7, 8], while ...

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Mechanisms Underlying the Antifatigue Effects of the Mycelium Extract of Cordyceps (Paecilomyces hepiali, CBG CS 2) in Mice in the Forced Swimming Test

Mechanisms Underlying the Antifatigue Effects of the Mycelium Extract of Cordyceps (Paecilomyces hepiali, CBG CS 2) in Mice in the Forced Swimming Test

... such as decreased muscular power and endurance, decreased motor skill performance, and mental lapses. Fa- tigue is also related to altered immunity of cell-mediated immune responses that are associated with T-cells and ...

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Papaver Rhoeas L. Hydroalcoholic Extract Exacerbates Forced Swimming Test-Induced Depression in Mice

Papaver Rhoeas L. Hydroalcoholic Extract Exacerbates Forced Swimming Test-Induced Depression in Mice

... Introduction: Depression is one of the most frequent psychiatric disorders in the world with occurs with higher incidence in women. In the present study, the effect of water-alcoholic extract of Papaver rhoeas L. on ...

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A role for serotonin in the antidepressant activity of NG Nitro L arginine in the rat forced swimming test

A role for serotonin in the antidepressant activity of NG Nitro L arginine in the rat forced swimming test

... intermediate 5-hydoxytryptophan (5-HTP) following in vivo administration of the amino acid decarboxylase inhibitor, NSD 1015 (100mg/kg). L-NA (5-20mg/kg) dose dependently increased 5-HTP accumulation, particularly in the ...

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Antidepressant Like Activity of Methanolic Extract of the Seeds of Trachysperum ammi in Swiss Albino Mice

Antidepressant Like Activity of Methanolic Extract of the Seeds of Trachysperum ammi in Swiss Albino Mice

... Trachysperum ammi has been traditionally used for the treatment of neuro- logical disorders such as depression and anxiety. To date, T. ammi has re- ported for its chemical constituents in different diseases condition. ...

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Pharmacological potential of tocotrienols: a review

Pharmacological potential of tocotrienols: a review

... Oral administration of TRF on exercise endurance and oxidative stress in forced swimming rats caused significant increase in the concentrations of liver glycogen, SOD, CAT, and GPx, as w[r] ...

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Psychopharmacological Profile of Hydroalcoholic Extract and P Hydroxybenzoic Acid Obtained from Bourreria huanita (Boraginaceae) in Mice

Psychopharmacological Profile of Hydroalcoholic Extract and P Hydroxybenzoic Acid Obtained from Bourreria huanita (Boraginaceae) in Mice

... The forced swimming test (FST) is the most widely used pharmacological model for assessing antidepressant activity [21] ...the swimming test. During the 6 min swimming test, immobility ...

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  PHYTOCHEMICAL SCREENING, ANTIDEPRESSANT AND IMMUNOMODULATORY EFFECTS OF AQUEOUS EXTRACT OF CISTUS LADANIFER L. FROM MOROCCO

  PHYTOCHEMICAL SCREENING, ANTIDEPRESSANT AND IMMUNOMODULATORY EFFECTS OF AQUEOUS EXTRACT OF CISTUS LADANIFER L. FROM MOROCCO

... Cistus ladanifer L. (CL) is a medicinal plant known for its therapeutic properties in Moroccan traditional medicine. The leaves with non-woody branches aqueous extract (AE) of CL showed both immunomdulatory and ...

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Antidepressant like effects of methanolic extract of Bacopa monniera in mice

Antidepressant like effects of methanolic extract of Bacopa monniera in mice

... Background: Bacopa monniera has been used as a cure for various ailments that include anxiety, epileptic disorders, dementia, blood purifier, cough and rheumatism, and some important local uses of the plant are in ...

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The novel cannabinoid receptor GPR55 mediates anxiolytic-like effects in the medial orbital cortex of mice with acute stress

The novel cannabinoid receptor GPR55 mediates anxiolytic-like effects in the medial orbital cortex of mice with acute stress

... The G protein-coupled receptor 55 (GPR55) is a novel cannabinoid receptor, whose exact role in anxiety remains unknown. The present study was conducted to explore the possible mechanisms by which GPR55 regulates anxiety ...

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Comparative study of Vetiveria zizanioides and Foeniculum vulgare extracts on behavioral despair of Wistar albino rats

Comparative study of Vetiveria zizanioides and Foeniculum vulgare extracts on behavioral despair of Wistar albino rats

... Both Forced swimming and Tail suspension test represents the behavioral despair model and they reproduce a state similar to human depression. These tests are quite sensitive and specific and the state of ...

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Evaluation of central nervous system (CNS) depressant activity of methanolic extract of Commelina diffusa Burm. in mice

Evaluation of central nervous system (CNS) depressant activity of methanolic extract of Commelina diffusa Burm. in mice

... [35]. However, CNS depressant effect was observed in the forced swimming test. Additionally, the experiment was extended to observe the tail suspension test allow as a fast and reliable screening of the ...

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Anti-Depression Effects Of Lithospermum Erythrorhizon Extract By Regulation Of Inflammation

Anti-Depression Effects Of Lithospermum Erythrorhizon Extract By Regulation Of Inflammation

... the Forced Swimming Test (FST) and made a depression animal model in order to investigate effects of Lithospermum erythrorhizon extract on stress-induced ...

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Antidepressant like effects of methanol extract of Hibiscus tiliaceus flowers in mice

Antidepressant like effects of methanol extract of Hibiscus tiliaceus flowers in mice

... The method used was similar to that described by Por- solt and colleagues [19]. Animals were randomly divided into four groups. Thirty minutes after the i.p. treatment with the methanol extract of H. tiliaceus (3, 10 and ...

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