fractional catabolic rate
Increased apo A I and apo A II fractional catabolic rate in patients with low high density lipoprotein cholesterol levels with or without hypertriglyceridemia
... The fractional catabolic rate (FCR) was equally elevated in groups 1 and 2 ...transport rate (TR) of apo A-I did not differ significantly among the groups and the apo A-II TR differed only ...
10
Elevated high density lipoprotein cholesterol levels correlate with decreased apolipoprotein A I and A II fractional catabolic rate in women
... susceptibility, but the metabolic mechanisms underlying elevated HDL-C levels are poorly understood. We now report the turnover of isologous radioiodinated HDL apolipoproteins, apo A-I and apo A-II, in 15 female subjects ...
9
Mechanism of hypertriglyceridemia in human apolipoprotein (apo) CIII transgenic mice Diminished very low density lipoprotein fractional catabolic rate associated with increased apo CIII and reduced apo E on the particles
... particles from low and high expressor mice were found to have a larger mean diameter, 55.2 +/- 16.6 and 58.2 +/- 17.8 nm, respectively, compared with 51.0 +/- 13.4 nm from control mice. In in vivo studies, radiolabeled ...
13
In vivo metabolism of complement: I Metabolism of the third component (C′3) in acquired hemolytic anemia
... The fractional catabolic rate and synthesis rate of C¢3 were at the upper limit of normal or were increased above normal in patients who had warm antibody autoimmune hemolytic anemia with ...
17
Rapid in vivo transport and catabolism of human apolipoprotein A IV 1 and slower catabolism of the apoA IV 2 isoprotein
... mean fractional catabolic rate (FCR) for apoA-IV-1 of ...transport, rate of apoA-IV-1 was ...production rate (r = 0.84, P < 0.001) and not correlated with apoA-IV fractional ...
10
Influence of age on the metabolism of plasma low density lipoproteins in healthy males
... 0.02) fractional catabolic rate of LDL apo B ...production rate of LDL apo B did not differ significantly between the ...reduced fractional catabolic rate of LDL apo B in ...
7
Increased sphingomyelin content of plasma lipoproteins in apolipoprotein E knockout mice reflects combined production and catabolic defects and enhances reactivity with mammalian sphingomyelinase
... Apolipoprotein E knockout (apoE0) mice accumulate atherogenic remnant lipoproteins in plasma. We now provide evidence that these particles are enriched in sphingomyelin (SM), and explore the mechanisms and possible ...
9
Dietary fat increases high density lipoprotein (HDL) levels both by increasing the transport rates and decreasing the fractional catabolic rates of HDL cholesterol ester and apolipoprotein (Apo) A I Presentation of a new animal model and mechanistic studies in human Apo A I transgenic and control mice
... transport rate (TR) and decreased the fractional catabolic rate of HDL cholesterol ester (CE) and apo A-I, with the largest effect on HDL CE ...
8
Metabolism of human immunoglobulin D (IgD)
... A constant figure for fractional catabolic rate was obtained only when the urinary activity was expressed as a fraction of intravascular radioactivity, indicating that catabolism of IgD [r] ...
13
In Vivo Studies of Serum C reactive Protein Turnover in Rabbits
... equated fractional catabolic rate to fractional disappearance rate, since the rate constant for passage of CRP from vascular to extravascular compartment can be assumed to be ...
8
Analysis of a compartmental model of endogenous immunoglobulin G metabolism with application to multiple myeloma
... production rate of monoclonal IgG correspondingly decreases, resulting in a fall in serum monoclonal IgG ...synthesis rate per cell were measured in 11 patients with IgG ...the fractional ...
18
Glomerular permeability of macromolecules Effect of molecular configuration on the fractional clearance of uncharged dextran and neutral horseradish peroxidase in the rat
... fractional clearances were determined for both test macromolecules in five Wistar-Furth rats. The results indicate that for a molecular radius of 28.45 A, as measured by gel filtration, the sugar polymer has a ...
6
Complement metabolism in man: hypercatabolism of the fourth (C4) and third (C3) components in patients with renal allograft rejection and hereditary angioedema (HAE)
... The catabolic rates of these complement proteins were determined by analysis of the disappearance of plasma protein-bound radioactivity (k m ), and by direct measurement of urinary excretion of radioactivity (k u ...
12
Comparative Analysis of Farrow Fractional Structure Rate Converter
... Farrow differentiating Interpolation filter provides another approach for implementing fractional delay filters using LaGrange polynomials. It uses piecewise approximation of the filter into a polynomial that ...
13
Strategies for optimal calorie administration in critically ill patients
... Energy and protein in critically ill patients with AKI: a prospective, multicenter observational study using indirect calorimetry and protein catabolic rate. de Goes CR, Berbel-Bufarah M[r] ...
9
Metabolism of very low density lipoproteins after cessation of cholesterol feeding in rabbits A factor potentially contributing to the slow regression of atheromatous plaques
... diet, fractional catabolic rates of plasma clearance of 125I-labeled VLDL were reduced ...VLDL catabolic rate was increased considerably ...
9
Synchronous deficits in cumulative muscle protein synthesis and ribosomal biogenesis underlie age related anabolic resistance to exercise in humans
... recruits. Since loss of muscle mass beyond 70 years of age occurs at a rate of 0.5–1% year − 1 (and assuming no changes in MPB), daily MPS would only need to be decreased 0.0015–0.003% day − 1 to account for such ...
19
Albumin metabolism: effect of the nutritional state and the dietary protein intake
... in catabolic rate after 3-5 days on a low protein diet ...The catabolic rate could return to normal within 3 wk in a malnourished child fed 4 g of protein/kg per ...synthetic rate was ...
16
Effects of chronic ethanol intake on mobilization and excretion of cholesterol in baboons
... However, the total amount of free cholesterol being turned over total or absolute catabolic rate was significantly increased, mainly as a reflection of the higher plasma cholesterol conc[r] ...
12
Measuring metabolic rates of small terrestrial organisms by fluorescence based closed system respirometry
... metabolic rate (MR) are difficult to compare across diverse species because patterns of ecology and evolution influence both MR (Isaac and Carbone, 2010; White and Kearney, 2014) and its method of measurement ...
8