Fracture repair
A Mechano Regulation Model of Fracture Repair in Vertebral Bodies
... vertebral fracture repair, where a multi-scale finite element model of a spinal segment was used to predict the magnitude of various biophysical stimuli acting in the callus surrounding regenerating ...
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Dnmt3b ablation impairs fracture repair through upregulation of Notch pathway
... DNA methylation is highly responsive to environmental stimuli as it broadly regulates the expression of growth factors, receptors, and transcription factors and coordinates signaling networks at the genome level (32, ...
17
NOTCH signaling in skeletal progenitors is critical for fracture repair
... from 2-month-old WT C57BL6/J mice treated with either 10 μM N-[(3,5-difluorophenyl)acetyl]-l-alanyl-2-phenyl]glycine-1,1-di- methylethyl ester (DAPT) (Calbiochem), a γ-secretase inhibitor that inhibits all NOTCH ...
12
Fibrinolysis is essential for fracture repair and prevention of heterotopic ossification
... in fracture repair appears to be fibrin clearance in support of efficient fracture callus neovascularization and bone formation, our studies do not formally exclude that plasmin also supports the ...
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Thrombin related peptide TP508 promoted fracture repair in a mouse high energy fracture model
... of fracture repair [17] and early studies have noted that TP508 may have positive effect on ...and fracture gap areas and significantly reduced scar formation in the groups receiving TP508 ...
10
Fracture repair requires TrkA signaling by skeletal sensory nerves
... signaling pathway (8). Because NGF is received by sensory nerve axons distant to their cell body, a unique mechanism has evolved to shuttle signals to the neuronal cell body. Following activation, neurotrophin-receptor ...
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Myogenic progenitors contribute to open but not closed fracture repair
... the fracture was made, its position was confirmed using a digital x-ray machine (Faxitron X- ray ...the fracture site was subsequently opened and the local periosteum stripped for ~3 mm each side of the ...
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From isolation to implantation: a concise review of mesenchymal stem cell therapy in bone fracture repair
... Compromised bone-regenerating capability following a long bone fracture is often the result of reduced host bone marrow (BM) progenitor cell numbers and efficacy. Without surgical intervention, these malunions ...
7
A prospective, double-blinded, randomized comparison of ultrasound-guided femoral nerve block with lateral femoral cutaneous nerve block versus standard anesthetic management for pain control during and after traumatic femur fracture repair in the pediatric population
... femoral fracture (upper, middle, or lower ...surgical repair may impact the distribution that requires postoperative coverage to ensure adequate ...for fracture repair within this study, ...
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Optimal bone fracture repair requires 24R,25 dihydroxyvitamin D3 and its effector molecule FAM57B2
... the fracture site to exert beneficial effects, or whether 24R,25(OH) 2 D 3 from the circulation is ...the repair callus, local syn- thesis of 24R,25(OH) 2 D 3 may contribute significantly to the healing ...
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Placental growth factor mediates mesenchymal cell development, cartilage turnover, and bone remodeling during fracture repair
... bone fracture healing. Fracture repair in mice lacking PlGF was impaired and characterized by a massive accumulation of cartilage in the callus, remi- niscent of delayed- or nonunion ...bone ...
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Anaesthesia of three young grey seals (Halichoerus grypus) for fracture repair
... Three young grey seals (Halichoerus grypus) were presented separately for fracture repair to the veterinary teaching hospital of University College Dublin. The seals were premedicated with a combination of ...
6
FGFR3 deficient mice have accelerated fracture repair
... during fracture repair [20, 21], indicating that FGFR3 may regulate the cartilaginous callus formation and replacement by ...in fracture healing using unstabilized fracture model of mice ...
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Expression of four growth factors during fracture repair
... Int I De\' BioI ~n 573 579 (199 1) 573 Origillal Arlie/I' Expression of four growth factors during fracture repair WilLIAM T BOURQUE", MICHAEL GROSS' and BRIAN K HAll' JBiology Department and 2Divisio[.] ...
7
Computational techniques for the assessment of fracture repair
... predict fracture healing and thereby help clinicians to customize ...a fracture gap and adapting the models for case-specific simulation may provide more accurate examination of the relationship between ...
21
Chemical characterization of wound ointment (WO) and its effects on fracture repair: a rabbit model
... during fracture healing in rabbit radius fracture model for the first ...mote fracture healing in China, but it’s unacquainted for other ...accelerated fracture healing were also not widely ...
10
Application of Rapid Prototyping in Trauma Surgery: Clavicle fracture Repair – a Clinical Study
... the fracture shows skin tenting, open fractures, the presence of neurovascular compromise, multiple trauma or fractures with displacement and shortening, surgical treatment may be recommended1, 9, 12, 13, ...15-B ...
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<p>Simultaneous curvature correction at the time of the penile fracture repair: surgical and functional outcomes</p>
... surgical repair of the PF noted that in the immediate repair group, the percent of patients with postoperative ED, tunical scars, and curvature were ...PF repair is around ...the repair are ...
6
Diagnosis and management of a trapped lung or diaphragm by fractured ribs: analysis of patients undergoing rib fracture repair
... management of a trapped lung using thoracoscopic re- lease without SSRF in the acute stage [4]. Schots et al. reported using thoracoscopic release with SSRF [5]. Most of our patients were not in the acute stage; they ...
6
Surgeons' beliefs and perceptions about removal of orthopaedic implants
... Surgeons tended towards informing patients about the need for later implant removal at the time of fracture repair mean rating 7.6, 95% CI 7.4 – 7.8.. Table 3 summarizes the findings fro[r] ...
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