Freund's adjuvant
Evaluation of Anti-Arthritic Activity of The Ethanolic Extract of Mimosa Pudica Linn. in Complete Freund’s Adjuvant Induced Arthritis in Wistar Rats
... complete Freund‟s adjuvant (CFA) act by prolonging the lifetime of injected autoantigen, by stimulating its effective delivery to the immune system and by providing a complex set of signals to the ...
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Experimental inflammation following dural application of complete Freund’s adjuvant or inflammatory soup does not alter brain and trigeminal microvascular passage
... Background: Migraine is a paroxysmal, disabling primary headache that affects 16 % of the adult population. In spite of decades of intense research, the origin and the pathophysiology mechanisms involved are still not ...
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Production and Preclinical Evaluation of Plasmodium falciparum MSP-119 and MSP-311 Chimeric Protein, PfMSP-Fu24
... Freund’s adjuvant. While Freund’s adjuvant, GLA-SE, and Adjuplex produced very high antibody titers, other aspects of the antibody response, such as recognition of native antigen on parasite (by IFA) and ...
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Interleukin-6: an emerging regulator of pathological pain
... Interleukin-6 is an inflammatory cytokine with wide-ranging biological effects. It has been widely demonstrated that neuroinflammation plays a critical role in the development of pathological pain. Recently, various ...
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Dog vaccination with EgM proteins against Echinococcus granulosus
... with Freund ’ s adjuvant induced protective efficacy against ...However, Freund ’ s adjuvant is not a suitable adjuvant for vaccination of ...as adjuvant to confirm ...
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The Protective Effect of Ethanolic Extract of Sida Tiagii Bhandari Seeds Against Complete Freunds Adjuvant Induced Experimental Animal Model of
... The acute phase response can be attributed to its anti-inflammatory activity. As it is well known that the chronic phase can be reversed by a potent immunomodulator. This activity could be attributed to the presence of ...
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Evaluating the immune responses of mice to subcutaneous immunization with Helicobacter pylori urease B subunit
... Previous studies have proven that IL-4 is a Th2-type representative cytokine which plays a key role in allergic inflammation [16]. Production of high level of IL-4 may indicate preferential activation of Th2 cells. ...
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Comparison of the adjuvant effect of propolis and Freund on the efficacy of Aeromonas hydrophila vaccine in common carp (Cyprinus carpio)
... Freund’s adjuvant is a well-known classical oil based adjuvant with strong adjuvanticity effects that has been used for years in veterinary vaccines (Gjessing et ...
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Retinal pathology in experimental optic neuritis is characterized by retrograde degeneration and gliosis
... Complete Freund ’ s adjuvant; CNS: Central nervous system; DAPI: 4 ′ , 6- diamidino-2-phenylindole; dpi: days post immunisation; EAE: Experimental autoimmune encephalomyelitis; GCL: Ganglion cell ...
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Anxiolytic effects of Formononetin in an inflammatory pain mouse model
... Chronic pain is commonly accompanied with anxiety disorder, which complicates treatment. In this study, we investigated the analgesic and anxiolytic effects of Formononetin (FMNT), an active component of traditional ...
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Repeated administration of mazindol reduces spontaneous pain-related behaviors without modifying bone density and microarchitecture in a mouse model of complete Freund’s adjuvant-induced knee arthritis
... While these studies suggest a role of dopaminergic sig- naling in the pathogenesis of RA, there have been no studies evaluating the role of dopaminergic signaling in the develop- ment or maintenance of arthritic joint ...
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Topical dura mater application of CFA induces enhanced expression of c-fos and glutamate in rat trigeminal nucleus caudalis: attenuated by KYNA derivate (SZR72)
... Complete Freund ’ s Adjuvant (CFA) onto the dura mater caused activation in rat trigeminal ganglion (TG) which was abolished by a systemic administration of kynurenic acid (KYNA) derivate ...
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Profiling the microRNA signature of the peripheral sensory ganglia in experimental autoimmune encephalomyelitis (EAE)
... Freund’s adjuvant (CFA) at a concentration of 1.5 mg/ ml. An additional intraperitoneal injection of 300 ng of pertussis toxin in 0.2 ml saline was given on the day of induction as well as 48 h later. Control ...
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Adjuvants for peptide-based cancer vaccines
... IFA is a water-in-oil emulsion, identical to Complete Freund’s Adjuvant (CFA) but without the heat-killed Mycobacteria tuberculosis to avoid acute granulomatous lesions at vaccine sites. It has previously been ...
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A retrospective study of concurrent chemoradiotherapy plus S-1 adjuvant chemotherapy on curative effect for treatment of patients with N3 stage nasopharyngeal carcinoma
... oral S-1 as adjuvant chemotherapy should be further evaluated in NPC, and S-1 may be better used for about 1 year after ...the S-1 blood concentration in vivo for a long ...
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Predictors of success in selective laser trabeculoplasty for primary open angle glaucoma in Chinese
... attributed to the fact that the pre-SLT IOP in our population was medically controlled with topical antiglaucoma medica- tion prior to SLT (17.7 ± 4.1 mmHg while on 2.4 ± 1.2 types of antiglaucoma eye drops). SLT was ...
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Prognosis of the intrahepatic cholangiocarcinoma after resection: hepatitis B virus infection and adjuvant chemotherapy are favorable prognosis factors
... of adjuvant chemotherapy and radiation in ICC remains controversial ...identified adjuvant chemotherapy was an independ- ent prognostic factor which was associated with an im- proved median survival of 15 ...
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Future possibilities in the prevention of breast cancer: Breast cancer prevention trials
... small and follow up in the Italian trial [6 • ] is relatively short. The NSABP study [3 • ] results are biologically plausible and in accord with the risk reduction seen in the contralat- eral breast in the ...
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R-CHOP versus R-CVP in the treatment of follicular lymphoma: a meta-analysis and critical appraisal of current literature
... Verstovsek S, Younes A, Pro B, Lee MS, Ayala A, McLaughlin P: Improvement of overall and failure-free survival in stage IV follicular lymphoma: 25 years of treatment experience at The University of Texas ...
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Survival outcomes of patients with advanced oral cavity squamous cell carcinoma treated with multimodal therapy: a multi-institutional analysis
... A total of four treatment groups were analyzed: 1) S- CRT, 2) S-RT, 3) CRT, and 4) RT. Group 1 patients underwent surgical resection and post-operative adju- vant CRT within 6–8 weeks of their operation. ...
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