FTO gene
Assessment of the FTO gene polymorphisms (rs1421085, rs17817449 and rs9939609) in exercise-trained men and women: the effects of a 4-week hypocaloric diet
... Results: Of the 47 subjects, 15 were of normal risk for obesity whereas 32 were carriers of the FTO gene risk alleles. Subjects were grouped based on their genotype for the three FTO SNPs (i.e., ...
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Original Article FTO gene polymorphisms and cholangiocarcinoma risk: a case-control study
... associated gene (FTO) located in chromosome ...The FTO protein express in many tis- sues, such as mesenteric fat, adipose, pancre- atic, liver, and hypothalamus ...in FTO that lead to a loss ...
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Evidence for the association between FTO gene variants and vitamin B12 concentrations in an Asian Indian population
... the FTO gene are known to be the stron- gest genetic predictor of obesity to date [41, ...the FTO locus trig- ger the overexpression of ghrelin mRNA, leading to higher levels of the hunger hormone, ...
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Interaction between FTO gene variants and lifestyle factors on metabolic traits in an Asian Indian population
... the FTO gene which is highly conserved across species and is located in the putative transcriptional factor (Cutl- like 1, CUTL1) binding site ...the FTO gene and hence it can be speculated ...
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EFFECT OF OBESITY ON INSULIN RESISTANCE AND HBA1C IN TYPE 2 DIABETIC PATIENTS AND ITS RELATIONS WITH FTO GENE SNP (RS9939609)
... that FTO variant rs9939609 is not associated with T2DM, but associated with obesity through its effect on ...of FTO gene variants on HDL-C ...
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Association study of the FTO gene polymorphisms with the risk of pulmonary tuberculosis in a sample of Iranian population
... The FTO gene is located on chromosome 16 (16q12.2). This gene encodes a protein that plays a role in regulation of food intake [10]. Obesity in fl uence patterns of oxidative stress and altered ...
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Study of genetic variations of FTO gene and its relationship to obese in Iraqi population
... This study included 120 of obese males with mean age 20-50 year and 50 aged-matched healthy males as a control. The obese patients classified into 3 groups based on Body Mass Index (BMI). DNA was isolated from the ...
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The Frequencies of Haplotypes of FTO Gene Variants and Their Association with the Distribution of Body Fat in Non-Obese Poles
... the FTO gene is involved in energy homeo- ...the FTO gene is not well known yet, although a few insights into its cellular role have recently been ...between FTO and RPGRIP1L (the human ...
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Similarities in Metabolic Flexibility and Hunger Hormone Ghrelin Exist Between FTO Gene Variants in Response to an Acute Dietary Challenge
... (FTO) gene has been associated with obesity, and studies have also shown that environmental/lifestyle interaction such as dietary intake might mediate this ...The FTO rs9939609 variant is genotyped ...
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Genetic association of SNPs in the FTO gene and predisposition to obesity in Malaysian Malays
... the FTO gene in Malaysian ...the FTO gene are in high LD in this ethnic ...of FTO were identified, neither of which confers an increased risk for obesity in this ...the FTO ...
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ASSOCIATION BETWEEN FAT MASS AND OBESITY ASSOCIATED (FTO) GENE POLYMORPHISM (RS9939609) AND LIPID PROFILE IN TYPE2 DIABETIC OBESE IRAQI MALE
... Biochemical characteristics (BMI, cholesterol, TG, VLDL-C, LDL-C, and HDL-C) of T2DM obese patients were analyzed with respect to the distribution of the genotypes. Genotypes of the FTO gene were considered ...
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FTO gene polymorphisms and obesity risk: a meta-analysis
... Of the SNPs that were reported to associate with obesity, rs9939609 has been of particular interest since it was discovered by Frayling et al. [4] The associations of other SNPs in the FTO gene with obesity ...
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Genetic association between antipsychotic induced weight gain and FTO gene in a Sri Lankan population
... Second gene- ration antipsychotics probably cause weight gain by acting on receptors which are involved in food intake and fat metabolism such as 5HT2C and DRD2 ...the FTO gene is involved in fat ...
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Role of a common variant of Fat Mass and Obesity associated (FTO) gene in obesity and coronary artery disease in subjects from Punjab, Pakistan: a case control study
... that FTO variant is associated with increased risk for hypertension through the regulation of sympathetic ner- vous system ...the FTO variant could increase the risk of CAD through another mechanism, mainly ...
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Original Article Correlation of FTO gene polymorphisms with osteoporosis risk
... (FTO) gene (rs7206790 and rs9939609) and osteoporosis ...gender. FTO gene rs7206790 and rs9939609 polymorphisms were genotyped via polymerase chain reaction-restriction fragment length ...
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Metabolic mechanisms of the fat mass and obesity-associated (FTO) gene
... (FTO) gene has been strongly linked to an increased obesity risk through numerous genome wide association (GWA) studies over the past ...of FTO, and to determine the impact of physical stress (in the ...
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Assessment of the FTO gene polymorphisms in male patients with metabolic syndrome
... the FTO gene SNPs on MetS risk or other metabolic parameters are simply due to a lack of sta- tistical ...the FTO gene SNPs on obesity and related ...the FTO SNPs and anthropometric or ...
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Effects of breed, postnatal development, and nutrition on mRNA expression of the FTO gene in porcine muscle and its relationship with intramuscular fat deposition
... study, FTO mRNA expression appeared to follow the same ...that FTO mRNA expression is involved in the regulation of IMF deposition dur- ing the growth of ...the FTO gene in IMF content, this ...
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Gene variants in the FTO gene are associated with adiponectin and TNF-alpha levels in gestational diabetes mellitus
... the FTO SNPs rs8050136 and rs9939609 with GDM, in accordance with Cho et ...the FTO gene may be apparent only in populations with higher minor allele frequency ...
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Fat mass and obesity associated (FTO) gene and hepatic
... fasting) may stimulate hepatic FTO expression, leading to the increased expression of gluconeogenic genes. 234[r] ...
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