G protein α subunit
Light-dependent roles of the G-protein α subunit GNA1 of Hypocrea jecorina (anamorph Trichoderma reesei)
... rimeric G-protein signaling, as recently also shown for ...of G- protein-mediated signal transduction in regulation of cel- lulase gene expression were provided by [26] in describing the ...
15
The G-Protein α-Subunit GasC Plays a Major Role in Germination in the Dimorphic Fungus Penicillium marneffei
... The opportunistic human pathogen Penicillium marneffei exhibits a temperature-dependent dimorphic switch. At 25⬚, multinucleate, septate hyphae that can undergo differentiation to produce asexual spores (conidia) are ...
14
Trichoderma atroviride G-Protein α-Subunit Gene tga1 Is Involved in Mycoparasitic Coiling and Conidiation
... Mas-7 activates Tga1 and raises cAMP levels. The activa- tion of heterotrimeric G proteins can be monitored by mea- suring the intrinsic GTPase activity of G␣. By following the method used for animal cells ...
12
Paternal versus maternal transmission of a stimulatory G protein α subunit knockout produces opposite effects on energy metabolism
... Disruption of alternative Gnas products could also play a role in dysregulation of energy metabolism. NESP55 is a maternal-specific Gnas gene product expressed primarily in the adrenal medulla and brain (16, 17). ...
10
A Phytophthora sojae G-Protein α Subunit Is Involved in Chemotaxis to Soybean Isoflavones
... to G ␣ subunit genes in other .../Physo1_1/Physo1_1.home.html; protein ID 108814), the gene was named PsGPA1, and full-length cDNA was obtained by RT-PCR amplification (see Table S1 in the ...
8
Gpa2, a G-Protein α Subunit Required for Hyphal Development in Candida albicans
... filamentation. G proteins are highly conserved at both the structural and sequence levels in all organisms, from yeast to human cells, and several muta- tions in other G␣ subunits that perturb the proper ...
10
Deletion of the α subunit of the heterotrimeric Go protein impairs cerebellar cortical development in mice
... AC: Adenylyl cyclase; Calb: Calbindin-D28K; cAMP: Cyclic AMP, 3 ′ ,5 ′ -cyclic adenosine monophosphate; CB1: Cannabinoid receptor 1; CFs: Climbing fibers; CNS: Central nervous system; DCN: Deep cerebellar nuclei; DEPC: ...
12
Overlap in signaling between Smoothened and the α subunit of the heterotrimeric G protein G₁₃
... C3H10T1/2 cells, as we had found these cells in previous studies to be quite difficult to trans- fect. We turned to recombinant adenoviruses. Pilot experiments with a recombinant adenovi- rus encoding LacZ revealed, ...
15
G protein γ subunit 7 induces autophagy and inhibits cell division
... (sigma), α-Tubulin, and β-Actin (1:1000, TransGen ...(Tanon). Protein levels were normalized to the matching densitometric value of the internal control α-Tubulin by ImageJ ...
16
The action of ethanol on G protein In silico and cellular/molecular evidences
... Gα protein in order to stimulate the nucleo- tide ...an α-helix and a ...hGαs subunit with the βγ subunit (black colour); this region consists of the N-terminus of the hGαs subunit and ...
9
The GTPase domain of Galphao contributes to the functional interaction of Galphao with the promyelocytic leukemia zinc finger protein
... abundant G proteins expressed in the brain [4], is classified as a member of the Gi/Go family by virtue of its sequence homology to Gi ...the α-subunits of Gi proteins, which inhibit adenylyl cyclase and ...
11
DETERMINE THE GPS MUTATIONS IN ACROMEGALIC SAMPLE OF IRAQI PATIENTS
... In over 90 percent of acromegaly patients, the overproduction of growth hormones is caused by a benign tumor of the pituitary gland, called an adenoma (Fieffe et al., 2011). Most pituitary tumors arise spontaneously and ...
7
The heterotrimeric G protein β subunit RGB1 is required for seedling formation in rice
... Plant survival begins with seed germination and the for- mation of seedlings under suitable environmental condi- tions. The mature seed consists of the embryo, endosperm, and seed coat, which are formed during ...
14
Heterotrimeric G-Protein Subunit Function in Candida albicans: both the α and β Subunits of the Pheromone Response G Protein Are Required for Mating
... heterotrimeric G protein (17, 43, 61). In contrast to many of the related G-protein-linked receptor signal- ing pathways identified in mammalian systems that use the acti- vated ␣ ...
9
McCune-Albright syndrome
... GNAS: G protein binding adenylyl cyclase stimulatory; cAMP: cyclic adenosine monophosphate; Gs alpha: G pro- tein α-subunit; MAS: McCune-Albright syndrome; GH: growth hormone; NF: ...
12
Altered mTOR and Beclin-1 mediated autophagic activation during right ventricular remodeling in monocrotaline-induced pulmonary hypertension
... monophosphate-activated protein kinase (AMPK)/ mammalian target of rapamycin (mTOR) and the other is hypoxia inducible factor 1 α (HIF-1 α )/B-cell lymphoma 2 (Bcl2)/adenovirus E1B 19 kDa ...
15
The Gβ-Subunit-Encoding Gene bpp1 Controls Cyclic-AMP Signaling in Ustilago maydis
... heterotrimeric G proteins. Of four G ␣ subunits in ...a G  subunit participates in pheromone signaling, we isolated the single  subunit gene, bpp1, from ...heterotrimeric G ...
9
The polymorphism of G protein β3 subunit C825T and cancer risk: A Meta-analysis
... To acquire all the studies that have association of the GNB3 C825T polymorphism with cancer risk, we searched the PubMed, Wanfang, CNKI (China National Knowledge Infrastructure) database, using the terms “GNB3 ...
10
Coupling H(+) transport to rotary catalysis in F type ATP synthases: structure and organization of the transmembrane rotary motor
... 1998). Subunit b is anchored in the membrane via a single transmembrane helix (TMH) at the N terminus, the structure of the segment having been determined recently using NMR (Dmitriev et ...1999b). Subunit ...
9
Characterization of two ETFDH mutations in a novel case of riboflavin-responsive multiple acyl-CoA dehydrogenase deficiency
... because DL-carnitine determined the appearance of 4– 5 liquid discharges per day. Only after one month, she had difficulty to move from the supine to the sitting position, weakness of the trunk muscles and external ...
8