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Gamma-delta T cells

Preferential activation and expansion of human peripheral blood gamma delta T cells in response to Toxoplasma gondii in vitro and their cytokine production and cytotoxic activity against T  gondii infected cells

Preferential activation and expansion of human peripheral blood gamma delta T cells in response to Toxoplasma gondii in vitro and their cytokine production and cytotoxic activity against T gondii infected cells

... if gamma delta T cells participate in the immune response to Toxoplasma ...human gamma delta T cells occurred when peripheral blood T cells from ...

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Case Report Primary cutaneous B-cell lymphoma with abundant reactive gamma/delta T-cells within the skin lesion and peripheral blood

Case Report Primary cutaneous B-cell lymphoma with abundant reactive gamma/delta T-cells within the skin lesion and peripheral blood

... Abstract: T-cell/histiocyte-rich diffuse large B-cell lymphoma is characterized by abundant reactive T-cell and histio- cyte infiltration within nodal diffuse large B-cell lymphoma, and only limited cases ...

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Dual antigenic recognition by cloned human gamma delta T cells

Dual antigenic recognition by cloned human gamma delta T cells

... of gamma delta T cells is still ...peripheral gamma delta T cells bear a V gamma 9/V delta 2 T cell receptor, and display nonclonal reactivity ...

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Selective expansion of human gamma delta T cells by monocytes infected with live Mycobacterium tuberculosis

Selective expansion of human gamma delta T cells by monocytes infected with live Mycobacterium tuberculosis

... of gamma delta T cells in draining lymph nodes and ...humans, gamma delta T cell lines with reactivity to mycobacterial antigens have been derived from synovial fluid of a ...

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Predominant activation and expansion of V gamma 9 bearing gamma delta T cells in vivo as well as in vitro in Salmonella infection

Predominant activation and expansion of V gamma 9 bearing gamma delta T cells in vivo as well as in vitro in Salmonella infection

... Gamma delta T cell receptor-positive cells (gamma delta T cells) have recently been implicated to play a role in the protection against infectious ...on ...

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Pregnancy and gamma/delta T cells: Taking on the hard questions

Pregnancy and gamma/delta T cells: Taking on the hard questions

... γδT cells at other mucosal sites [20], the decidual γδT cells are activated but ...γδT cells do not express FasL on their surface but store preformed FasL in the granules, and can rapidly mobilize it ...

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Staphylococcus aureus Infection of Mice Expands a Population of Memory gamma delta T Cells That Are Protective against Subsequent Infection

Staphylococcus aureus Infection of Mice Expands a Population of Memory gamma delta T Cells That Are Protective against Subsequent Infection

... γδ T cells identified as the primary source of innate IL-17 in models of acute ...γδ T cells that exhibit a more rapid expansion and clearance of infection than in the primary response and, in ...

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Expansions of IFN γ producing Gamma delta T cells in patients with asymptomatic persistent hepatitis B virus infection

Expansions of IFN γ producing Gamma delta T cells in patients with asymptomatic persistent hepatitis B virus infection

... Vδ2 T cells and reduced IFN-γ expression, with the greatest depletions observed in patients with the highest viral loads ...Vδ2 T cells in a cohort of asymptomatic HBV patients with low viral ...

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Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells

Interleukin-15 enhances the proliferation, stimulatory phenotype, and antitumor effector functions of human gamma delta T cells

... γδ T cell cultures to immunophe- ...γδ T cells of healthy donors at day 0, with a small preponderance for the naïve and cen- tral memory phenotype, the vast majority of expanded cells were ...

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Expression of non-secreted IL-4 is associated with HDAC inhibitor-induced cell death, histone acetylation and c-Jun regulation in human gamma/delta T-cells

Expression of non-secreted IL-4 is associated with HDAC inhibitor-induced cell death, histone acetylation and c-Jun regulation in human gamma/delta T-cells

... (clone 8D4-8), FITC-Vδ2 and Brilliant violet 605-IL-4 (clone MP4-25D2) and gating on live/dead fixable far-red dye negative cells. 4 independent experiments were showing mean ± S.E. Samples were acquired on BD LSR ...

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T10B9 monoclonal antibody: A short-acting nonstimulating monoclonal antibody that spares γδ T-cells and treats and prevents cellular rejection

T10B9 monoclonal antibody: A short-acting nonstimulating monoclonal antibody that spares γδ T-cells and treats and prevents cellular rejection

... γδ T cells which may be important in infection and in the development of tolerance; and finally to support the thesis that a shorter acting more selective anti-T-lymphocyte monoclonal antibody may be ...

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Sendai virus pneumonia: evidence for the early recruitment of gamma delta T cells during the disease course.

Sendai virus pneumonia: evidence for the early recruitment of gamma delta T cells during the disease course.

... 4022-4027 0022-538X/94/$04.00+0 Copyright © 1994, American Society for Microbiology Sendai Virus Pneumonia: Evidence for the Early Recruitment of 'y7 T Cells during the Disease Course TO[r] ...

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Intraepithelial gamma/delta T cells in duodenal mucosa are related to the immune state and survival time in AIDS.

Intraepithelial gamma/delta T cells in duodenal mucosa are related to the immune state and survival time in AIDS.

... campylobacter enteritis (20.9%), the three with herpes simplex virus type 2 infection (median, 19.4%), and the four with sys- temic CMV infection (median, 17.5%). We also found high g/d IEL proportions in four patients ...

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Expansion of Gamma Delta T Cells - A Short Review on Bisphosphonate and K562-Based Methods

Expansion of Gamma Delta T Cells - A Short Review on Bisphosphonate and K562-Based Methods

... classic T cell exhaustion markers such as CTLA- 4, LAG3, TIM3 and ...Vγ9Vδ2 T cells were activated and highly cytotoxic against ZOL-treated cancer ...Vγ9Vδ2 T cells and day 17 ...

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Evidence for the involvement of gamma delta T cells in the immune response in Rasmussen encephalitis

Evidence for the involvement of gamma delta T cells in the immune response in Rasmussen encephalitis

... Coulter, Brea, CA). Fragments were sized on a Bioanalyzer instrument (Agilent Technologies, Inc. Santa Clara, CA), quantified by qPCR (KAPA library quant kit), and pooled. Libraries were sequenced on a MiSeq desktop ...

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Cellular and molecular basis of human gamma delta T cell activation  Role of accessory molecules in alloactivation

Cellular and molecular basis of human gamma delta T cell activation Role of accessory molecules in alloactivation

... to gamma delta T cell receptor, CD2, CD3, or CD11a were also inhibitory, whereas antibodies to alpha beta T cell receptor, CD4, CD5, and CD8 had no ...isolated gamma delta ...

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Clonal expansion of lung V delta 1+ T cells in pulmonary sarcoidosis

Clonal expansion of lung V delta 1+ T cells in pulmonary sarcoidosis

... gamma/delta T cells in the pathogenesis of pulmonary sarcoidosis, we studied lung and blood T cells from patients for preferential expression of particular ...

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Increased numbers of T lymphocytes with gamma delta positive antigen receptors in a subgroup of individuals with pulmonary sarcoidosis

Increased numbers of T lymphocytes with gamma delta positive antigen receptors in a subgroup of individuals with pulmonary sarcoidosis

... 60 cells/microliters, P less than ...CD3+ gamma delta+ T cells, owing to a striking increase in the number of CD3+ gamma delta+ T cells in a subgroup (7 of ...

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Longitudinal analysis of gamma delta T cell subsets during malaria infections in Malian adults

Longitudinal analysis of gamma delta T cell subsets during malaria infections in Malian adults

... γδ T cells was dominated by Vδ2− γδ T cells, which were higher than Vδ2+ γδ T cells in the majority of the volunteers in this ...γδ T cell sub- sets are the Vδ2+T ...

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Persistent Changes in Circulating and Intestinal gamma delta T Cell Subsets, Invariant Natural Killer T Cells and Mucosal Associated Invariant T Cells in Children and Adults with Coeliac Disease

Persistent Changes in Circulating and Intestinal gamma delta T Cell Subsets, Invariant Natural Killer T Cells and Mucosal Associated Invariant T Cells in Children and Adults with Coeliac Disease

... Vδ2 cells in blood [34], the authors’ definition of such cells, ‘abounding at sites of inflammation’ and displaying ‘immediate effector functions’ fit with our findings of an expanded population capable of ...

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