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ganglion-cell

Visual contrast detection cannot be predicted from surrogate measures of retinal ganglion cell number and sampling density in healthy young adults

Visual contrast detection cannot be predicted from surrogate measures of retinal ganglion cell number and sampling density in healthy young adults

... retinal ganglion cell ...retinal ganglion cells may have the functional consequence of steeper psychometric functions (smaller spread parameter) due to greater signal in response to a ...retinal ...

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Neurotrophic regulation of retinal ganglion cell synaptic
connectivity: from axons and dendrites to synapses

Neurotrophic regulation of retinal ganglion cell synaptic connectivity: from axons and dendrites to synapses

... Retinal ganglion cells (RGCs), the sole projection neurons from the retina, integrate, process, and convey all visual information transmitted to the brain (Dowling, ...the ganglion cell layer (GCL) ...

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Topoisomerase IIβ is required for lamina specific targeting of retinal ganglion cell axons and dendrites

Topoisomerase IIβ is required for lamina specific targeting of retinal ganglion cell axons and dendrites

... Pou4f3:mGFP+ ganglion cell (GC) dendrites innervate five sublaminae in wild type (C); arrows in I show three coarse sublaminae in the mutant IPL ...and ganglion cell layer (GCL) project ...

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Semaphorin 3d guides laterality of retinal ganglion cell projections in zebrafish

Semaphorin 3d guides laterality of retinal ganglion cell projections in zebrafish

... The optic chiasm is an important choice point at which retinal ganglion cell (RGC) axons either cross the midline to innervate the contralateral brain or turn back to innervate the ipsilateral brain. ...

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A novel retinal ganglion cell promoter for utility in AAV vectors

A novel retinal ganglion cell promoter for utility in AAV vectors

... Significant advances in gene therapy have enabled exploration of therapies for inherited retinal disorders, many of which are in preclinical development or clinical evaluation. Gene therapy for retinal conditions has led ...

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Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5

Rewiring the retinal ganglion cell gene regulatory network: Neurod1 promotes retinal ganglion cell fate in the absence of Math5

... amacrine cell fate, and are capable of producing excess numbers of amacrine cells when each of them is ectopically co-expressed with Pax6 or Six3 (Inoue et ...

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Matrix metalloproteinases are required for retinal ganglion cell axon guidance at select decision points

Matrix metalloproteinases are required for retinal ganglion cell axon guidance at select decision points

... To the best of our knowledge, this paper demonstrates for the first time that MMPs are involved in axon guidance. Although ADAM proteins have been implicated in axon guidance in species from worms to mice (Fambrough et ...

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Staggered cell intrinsic timing of ath5 expression underlies the
wave of ganglion cell neurogenesis in the zebrafish retina

Staggered cell intrinsic timing of ath5 expression underlies the wave of ganglion cell neurogenesis in the zebrafish retina

... Even cell-non-autonomous effects on neighboring cells are plausible given the close juxtaposition of cells in neural plate that will later give rise to the eye (Varga et ...

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The cell adhesion molecule NrCAM is crucial for growth cone behaviour and pathfinding of retinal ganglion cell axons

The cell adhesion molecule NrCAM is crucial for growth cone behaviour and pathfinding of retinal ganglion cell axons

... Single-cell cultures of embryonic day (E) 6 retinal cells were prepared as described (Avci et al., 2004; Halfter et al., 1983). Poly-L-lysine (PLL)-coated glass coverslips were incubated with either Laminin (5 μ ...

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The Relationship Between the Photopic Negative Response and Retinal Ganglion Cell Topography

The Relationship Between the Photopic Negative Response and Retinal Ganglion Cell Topography

... Simplistically, one might expect to find a linear relationship between RGC cell numbers and PhNR amplitude but several lines of evidence suggest this may not be the case. In pharmacologic experiments in macaque to ...

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Retinal specialization through spatially varying cell densities and opsin coexpression in cichlid fish

Retinal specialization through spatially varying cell densities and opsin coexpression in cichlid fish

... of ganglion cells and cone cells and quantify opsin coexpression in single cones to show these also vary across the ...reduced ganglion cell densities and increased opsin ...

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Original Article Additional criteria in diagnosis of transitional zone in Hirschsprung disease

Original Article Additional criteria in diagnosis of transitional zone in Hirschsprung disease

... of ganglion and glial cells in both plexuses in both HD zones, regardless of staining ...and ganglion cell ratio (GCI), especially in myenteric plexus, could be very important criteria for diagnosis ...

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Axonal Transport and Sorting of Herpes Simplex Virus Components in a Mature Mouse Visual System

Axonal Transport and Sorting of Herpes Simplex Virus Components in a Mature Mouse Visual System

... the cell ma- chinery necessary for synthesis of new ...retinal ganglion cell axons in adult ...retinal ganglion cells in the BALB/c mouse retina ...

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An intersellar collision tumor   ganglion cell tumor with pituitary adenoma

An intersellar collision tumor ganglion cell tumor with pituitary adenoma

... diuresis and no limb activity disorder or body convulsions. On examination patient was drowsy. The patient was able to fix and follow objects. Vision was 6/60 in both the eyes. Pupils were 3mm in size and reactive. On ...

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Wnt2b inhibits differentiation of retinal progenitor cells in the absence of Notch activity by downregulating the expression of proneural genes

Wnt2b inhibits differentiation of retinal progenitor cells in the absence of Notch activity by downregulating the expression of proneural genes

... the cell cycle exit has been shown to be important for proper retinal cell differentiation (Ohnuma et ...the cell cycle was the primary effect of Wnt2b, resulting in the inhibition of neuronal ...the ...

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Single cell RNA sequencing of stem cell derived retinal ganglion cells

Single cell RNA sequencing of stem cell derived retinal ganglion cells

... Retinal ganglion cells (RGCs) transmit visual information from the retina to the midbrain through the optic nerve. Many diseases, such as primary open angle glaucoma, Leber hereditary optic neuropathy and ...

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Targeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis

Targeted deletion of Hand2 in enteric neural precursor cells affects its functions in neurogenesis, neurotransmitter specification and gangliogenesis, causing functional aganglionosis

... affects cell proliferation (Hendershot et ...glial cell numbers in Hand2 mutant ENS suggested that loss of Hand2 function in the NEP cells might cause this ...apparent cell death in either wild-type ...

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The commissural ganglia of the lobster, homarus gammarus, (L)

The commissural ganglia of the lobster, homarus gammarus, (L)

... stomatogastric ganglion since it continues when the stomatogastric nerve is blocked with a sucrose ...stomatogastric ganglion preparations ( see above ) the commissural gastric drivers may be considered ...

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CONTRIBUTION OF THE Na+/H+ ANTIPORTER TO THE REGULATION OF INTRACELLULAR pH IN A CRAYFISH STRETCH RECEPTOR NEURONE

CONTRIBUTION OF THE Na+/H+ ANTIPORTER TO THE REGULATION OF INTRACELLULAR pH IN A CRAYFISH STRETCH RECEPTOR NEURONE

... antiport. Between these two extremes, the crayfish neurone (Moody, 1981) exhibited an intermediate rate of pHi recovery, with both mechanisms contributing substantially to pHi regulation under normal conditions. All ...

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Allatostatin peptides in the crab stomatogastric nervous system: inhibition of the pyloric motor pattern and distribution of allatostatin like immunoreactivity

Allatostatin peptides in the crab stomatogastric nervous system: inhibition of the pyloric motor pattern and distribution of allatostatin like immunoreactivity

... stomatogastric ganglion in crabs, where they elaborate in a rich array of varicosities, and the reproducible dose-dependent physiological effects of these peptides on the pyloric network suggest that crustacean ...

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